Mitochondrial Medicine
Mitochondrial Medicine

Author: Salvatore DiMauro

Publisher: CRC Press

Published: 2006-04-19

Total Pages: 1000

ISBN-13: 9780415390361

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Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.

Roadside Safety Features and Hydraulic, Hydrology, and Water Quality Issues
Roadside Safety Features and Hydraulic, Hydrology, and Water Quality Issues

Author: National Research Council (U.S.). Transportation Research Board

Publisher:

Published: 2000

Total Pages: 130

ISBN-13:

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Transportation Research Record contains the following papers: Evaluation of portable concrete barriers using finite element simulation (Marzougi, D, Bahouth, G, Eskandarian, A, Meczkowski and Taylor, H); Impact performance of the G4(1W) and G4(2W) guardrail systems : comparison under NCHRP report 350 test 3-11 conditions (Plaxico, CA, Ray, MH and Hiranmayee, K); Long-span guardrail system for culvert applications (Faller, RK, Sicking, DL, Polivka, KA, Rohde, JR and Bielenberg, BW); Transitions from guardrail to bridge rail that meet safety performance requirements (Buth, CE, Menges, WL, and Bligh, RP); Performance of breakaway cable and modified eccentric loader terminals in Iowa and North Carolina : in-service evaluation (Ray, MH and Hopp, JA); Safety effectiveness of upgrading guardrail terminals to NCHRP reports 350 standards (Ray, MH); Design and development of steel breakaway posts (Sicking, DL, Rohde, JR and Reid, JD); Evaluating human risk in side impact collisions with roadside objects (Ray, MH and Hiranmayee, K); In-service, performance-based roadside design policy : preliminary insights from Washington State's bridge rail study (Shankar, VN, Albin, RB, Milton, JC and Nebergall, M); Test level 4 bridge rails (Buth, CE, Menges, WL and Williams, WF); Estimation of time of concentration for Maryland streams (Thomas, WO, Monde, MC and Davis, SR); Temporal variations in heavy metal partitioning and loading in urban highway pavement sheet flow : implications for in situ treatment design (Sansalone, JJ and Glenn, DW); California Department of Transportation statewide storm water management program (Johnston, J, Yamaguchi, H and Frankel, A).