Normal and Abnormal Development of the Kidney
Author: Edith Louise Potter
Publisher:
Published: 1972
Total Pages: 328
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author: Edith Louise Potter
Publisher:
Published: 1972
Total Pages: 328
ISBN-13:
DOWNLOAD EBOOKAuthor: Ellis D. Avner
Publisher: Springer Science & Business Media
Published: 2009-08-20
Total Pages: 2059
ISBN-13: 3540763279
DOWNLOAD EBOOKHere is an extensive update of Pediatric Nephrology, which has become the standard reference text in the field. It is global in perspective and reflects the international group of editors, who are well-recognized experts in pediatric nephrology. Within this text, the development of kidney structure and function is followed by detailed and comprehensive chapters on all childhood kidney diseases.
Author: Xin J. Zhou
Publisher: Cambridge University Press
Published: 2017-03-02
Total Pages: 691
ISBN-13: 1316613984
DOWNLOAD EBOOKAn algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Author: Linda M. Ernst
Publisher: Springer Nature
Published: 2019-08-31
Total Pages: 429
ISBN-13: 3030114252
DOWNLOAD EBOOKThe first edition of Color Atlas of Fetal and Neonatal Histology was an important step in updating the histology texts available to practicing pathologists and pathology trainees who perform fetal autopsy and/or participate in research involving fetal tissues. It was a well-received volume that filled a major gap in pathology references related to normal histology and provided a comprehensive, state-of-the art review of fetal and neonatal histology. While the basics of fetal histology have changed little in the intervening years since publication of the first edition, this successor edition provides new insights and a fresh perspective. This book contains six new chapters including: blood vessels and lymphatics, external genitalia, eye, ear, skin, and maceration changes. Many existing chapters have also been expanded to address a greater breadth of fetal and neonatal histology such as postnatal testis development and the cardiac conduction system. The “Special Considerations” sections were also expanded in many chapters to address particularly problematic issues within individual organ systems. The book reviews the histology of the major organ systems in the fetus and neonate and provides detailed images, up-to-date references, and practical guidelines for identifying tissues across all gestational ages of development. The second edition of Color Atlas of Fetal and Neonatal Histology serves as the ultimate go-to resource for pathologists and researchers dealing with, and interested in, fetal and neonatal histology. It provides a comprehensive summary of the current status of the field with excellent and extensive illustrative examples that help guide the clinical study of fetal and neonatal histology and stimulate investigative efforts with fetal tissue.
Author: Juerg Hodler
Publisher: Springer
Published: 2018-03-20
Total Pages: 262
ISBN-13: 3319750194
DOWNLOAD EBOOKThis open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.
Author: K.J. Barteczko
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 116
ISBN-13: 3642583539
DOWNLOAD EBOOKThe testicular descent (descensus testis) is described in a complete series of human material from stage 14 CC to the adult state by using own phases. Central points of interest in this work are answers to questions which have been discussed controversially by generations of scientists and which are wrong or inadequately documented in most textbooks of embryology: Does an inner gonadal descent exist? What about origin, role and fate of gubernaculum H., processus vaginalis peritonei and gonadal ligaments? How do the annexes of testis come into their final position? The results are based on serial sections, scanning electron microscopy, three-dimensional reconstructions, microdissection and immunohistochemistry.
Author: Melissa Helen Little
Publisher: Academic Press
Published: 2015-08-06
Total Pages: 615
ISBN-13: 012800438X
DOWNLOAD EBOOKKidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. - Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities - Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally - Explains the underlying developmental mechanisms which influence the kidney's inherent repair capacity - Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine
Author: Lauri Saxen
Publisher: Cambridge University Press
Published: 1987-04-16
Total Pages: 185
ISBN-13: 0521301521
DOWNLOAD EBOOKAlthough this description of a model system for cell differentation and organogenesis emphasizes the mammalian kidney, detailed coverage is also given to the development of the transient excretory organs.
Author: Peter D. Vize
Publisher: Elsevier
Published: 2003-03-14
Total Pages: 534
ISBN-13: 0080521541
DOWNLOAD EBOOKOrganogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney. - Hundreds of color figures depicting key events in all aspects of kidney development - Full coverage of the genetic and cellular basis of kidney development - Analysis of the genetic basis of the major congenital kidney diseases
Author: Jong Hoon Park
Publisher: Springer
Published: 2016-10-12
Total Pages: 128
ISBN-13: 9811020418
DOWNLOAD EBOOKAutosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.