Contemporary Targeted Therapies in Rheumatology

Contemporary Targeted Therapies in Rheumatology

Author: Josef S. Smolen

Publisher: CRC Press

Published: 2007-10-18

Total Pages: 636

ISBN-13: 0203694147

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Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path


Rheumatology and Immunology Therapy

Rheumatology and Immunology Therapy

Author: Larry W. Moreland

Publisher: Springer Science & Business Media

Published: 2004-07-20

Total Pages: 933

ISBN-13: 3540206256

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Entries in a practical A to Z Format Highly therapy-focused Uniform and clearly arranged entries for ease of reference Comprehensive information on symptoms and therapeutical possibilities of rheumatologic and musculoskeletal diseases as well as drugs Written by leading experts in the field


New Developments in Antirheumatic Therapy

New Developments in Antirheumatic Therapy

Author: K. D. Rainsford

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 331

ISBN-13: 9400912536

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At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- 010gy in the past 5-10 years have enabled these tools to be applied extensive ly for developing further our understanding of the rheumatic disease processes. In some cases these molecular tools (e. g. ,),-interferon, interleukin- 2, T-cell antibodies) have been directly employed as therapies themselves. While the outcome from trials with such agents in rheumatoid arthritis in particular has not been as would have been hoped, these results as with cy closporin A and low-dose methotrexate in the therapy of rheumatoid arth ritis have given us important indications for the approach employing what are generally described as "immunomodulators" to control this disease. But this may not be the same type of approach which is desirable for all types of rheumatic conditions. Indeed, even the way which the present range of drugs and other therapies are applied may not be the most effective and safe means of treating different types of arthritic conditions.


Modern Therapeutics in Rheumatic Diseases

Modern Therapeutics in Rheumatic Diseases

Author: George C. Tsokos

Publisher: Springer Science & Business Media

Published: 2001-11-08

Total Pages: 648

ISBN-13: 1592592392

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Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.


Clinical Innovation in Rheumatology

Clinical Innovation in Rheumatology

Author: Jason Liebowitz

Publisher: CRC Press

Published: 2022-10-04

Total Pages: 434

ISBN-13: 1000684768

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Tremendous advances have been made in the field of rheumatology, profoundly changing our understanding of many rheumatologic conditions and creating a new frontier for effective treatments. This book explains the most significant advances in research and care and speculates as to what will be the future of rheumatology over the next several decades, including challenges and lessons learned from past experiences in the field. It highlights landmark research articles and scientific discoveries, discusses how big data, personalized medicine, new biomarkers for disease, and other technological revolutions will shape the future, making it a must-have resource for physicians from all regions of the world. Key Features • Includes concise yet thorough description of the landmark studies and scientific breakthroughs coupled with easy-to-follow organizational structure of chapters that are accessible to readers at different levels of training. • Brings together world-leading experts to provide a fresh perspective to trainees such as residents and fellows-in-training, as well as more senior clinicians and researchers across the field of rheumatology and in specialties such as cardiology, dermatology, pulmonology, nephrology, and neurology, all of whom care for patients with rheumatologic conditions. • Allows the authors to imagine and speculate about the evolution of the field of rheumatology in the coming decades. Examples of such speculative possibilities include use of synovial biopsy to predict response to treatment in rheumatoid arthritis, replacement of renal biopsy with urinary proteomics in diagnosing and classifying lupus nephritis, use of new therapeutics to obviate the need for steroids in the treatment of ANCA-associated vasculitis, and the use of machine learning to evaluate subtle changes in imaging for management of inflammatory arthritis.


Biologics for the Treatment of Rheumatoid Arthritis

Biologics for the Treatment of Rheumatoid Arthritis

Author: Ronald van Vollenhoven

Publisher: Springer

Published: 2015-12-22

Total Pages: 139

ISBN-13: 3319131087

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This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.


The New Arthritis Breakthrough

The New Arthritis Breakthrough

Author: Henry Scammell

Publisher: M. Evans

Published: 1998-04-25

Total Pages: 331

ISBN-13: 1590771702

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...can be miraculous for rheumatoid arthritis sufferers.— Health & Healing, Tomorrow's Medicine Today


Clinical Practice in Rheumatology

Clinical Practice in Rheumatology

Author: Maurice Barry

Publisher: Springer Science & Business Media

Published: 2003-06-12

Total Pages: 130

ISBN-13: 9781852337193

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The assessment and management of rheumatic diseases is challenging and many doctors are not confident of their abilities in this area. Those who want to rapidly learn the essentials of modern clinical rheumatology will find all the practical advice and information they need in this text. Written for senior house officers and residents in general (internal) medicine, health professionals in rheumatology, primary care doctors and medical students will also find it useful: Up-to-date information about new therapies Essentials of common and uncommon rheumatic diseases listed Practical advice on selecting appropriate tests, drug prescribing and patient information Patient-centred approach to management Useful rheumatology websites listed All you need in one handy pocket-sized resource


Best Practices and Challenges to the Practice of Rheumatology, An Issue of Rheumatic Disease Clinics of North America

Best Practices and Challenges to the Practice of Rheumatology, An Issue of Rheumatic Disease Clinics of North America

Author: Daniel J. Wallace

Publisher: Elsevier Health Sciences

Published: 2018-11-21

Total Pages:

ISBN-13: 0323655416

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Guest edited by Drs. Daniel J. Wallace and R. Swamy Venuturupalli, this issue of Rheumatic Disease Clinics will cover several key areas of interest related to Best Practices and Challenges to the Practice of Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles in this issue include, but are not limited to: The Economics of Rheumatology Practice in the United States, Manpower trends in rheumatology, Challenges to practicing rheumatology in an academic center, Challenges in practicing rheumatology in a government setting, Challenges to practicing rheumatology in a small private practice setting, Challenges to working in a large multispecialty organization, Challenges to practicing pediatric rheumatology, Clinical trials in rheumatology, Challenges in having an infusion center, Implementing treatment to target in the clinic, Future directions: implementing new technologies in clinical practice, Possible Challenges in Optimizing Medical Education for Rheumatologists, and the challenges of approaching and managing gout.