Principles of Regenerative Medicine
Principles of Regenerative Medicine

Author: Anthony Atala

Publisher: Academic Press

Published: 2010-12-16

Total Pages: 1203

ISBN-13: 0123814235

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Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Translating Regenerative Medicine to the Clinic
Translating Regenerative Medicine to the Clinic

Author: Jeffrey Laurence

Publisher: Academic Press

Published: 2015-11-18

Total Pages: 356

ISBN-13: 0128005521

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Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. - Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic - Covers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field - Contains extensive pedagogical updates aiming to improve the education of translational researchers in this field - Provides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine

Future Strategies for Tissue and Organ Replacement
Future Strategies for Tissue and Organ Replacement

Author: Julia M. Polak

Publisher:

Published: 2002

Total Pages: 427

ISBN-13: 9781860943102

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Several textbooks have been published that discuss just one or two of the areas concerning tissue and organ replacement. This important book brings together all the different approaches for the first time. The contributors are established experts in their respective fields.The multidisciplinary nature of the text will appeal to students, scientists and clinicians from a wide spectrum of disciplines who are considering a future in organ replacement therapy, as well as to those who have so far only learnt of the developments in organ transplantation or replacement in the lay media. The field is moving very fast indeed — transplant surgeons continue to redefine what is possible and new products that were just laboratory curiosities a few years ago are beginning to enter clinics around the world and improve the quality of life for thousands of people. The promise of the various technologies described in this book, if realised, will make a profound and lasting impact on both the way the health care industry operates and the way we view the human body.

Stem Cells in Clinical Practice and Tissue Engineering
Stem Cells in Clinical Practice and Tissue Engineering

Author: Rakesh Sharma

Publisher: BoD – Books on Demand

Published: 2018-05-02

Total Pages: 353

ISBN-13: 1789230101

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Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Biomaterials for Organ and Tissue Regeneration
Biomaterials for Organ and Tissue Regeneration

Author: Nihal Vrana

Publisher: Woodhead Publishing

Published: 2020-03-20

Total Pages: 847

ISBN-13: 0081029071

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Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. - Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities - Encompasses the classic paradigm of tissue engineering for creation of new functional tissue - Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations

Epigenetics and Regeneration
Epigenetics and Regeneration

Author:

Publisher: Academic Press

Published: 2019-05-24

Total Pages: 544

ISBN-13: 0128148802

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Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. - Provides a foundational overview of epigenetics in regenerative medicine - Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice - Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways - Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine

Innovative Medicine
Innovative Medicine

Author: Kazuwa Nakao

Publisher: Springer

Published: 2015-10-13

Total Pages: 330

ISBN-13: 4431556516

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This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Tissue Engineering for Artificial Organs, 2 Volume Set
Tissue Engineering for Artificial Organs, 2 Volume Set

Author: Anwarul Hasan

Publisher: John Wiley & Sons

Published: 2017-06-19

Total Pages: 762

ISBN-13: 3527338632

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A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

In Situ Tissue Regeneration
In Situ Tissue Regeneration

Author: Sang Jin Lee

Publisher: Academic Press

Published: 2016-07-17

Total Pages: 460

ISBN-13: 012802500X

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In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body's ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body's own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. - Explores the body's ability to mobilize endogenous stem cells to the site of injury - Details the latest strategies developed for inducing and supporting the body's own regenerating capacity - Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume - Features chapter authors and editors who are authorities in this emerging field - Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry

Advances In Tissue Engineering
Advances In Tissue Engineering

Author: Julia M Polak

Publisher: World Scientific

Published: 2008-08-20

Total Pages: 947

ISBN-13: 1908978902

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Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field./a