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Neurosecretion: Secretory Mechanisms

Author: José R. Lemos

Publisher: Springer Nature

Published: 2020-03-31

Total Pages: 318

ISBN-13: 3030229890

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley

Neurosecretion - The Final Neuroendocrine Pathway

Author: F. Knowles

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 348

ISBN-13: 3662125870

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This volume marks the end of twenty years of neurosecretion during which there were five symposia, namely Naples (1953), Lund (1957), Bristol (1961), Strasbourg (1966), and Kiel (1970). In comparison with these symposia an exceptionally large number of papers were read at this the sixth symposium, in London, and for economic reasons it has not been possible to publish all the papers in extenso. The editors have therefore been obliged to undertake the unenviable work of selection, a task made all the more difficult by the excel lence and importance of contributions of the symposium. We felt that it was of the utmost importance at this moment in the history of neurosecretion to present as complete a picture as possible of the present state of the subject in relation to the past and opportunities for the future. We have therefore given some preference to papers with a strong review element, research papers in areas of current importance and contributions which deal with recently developed techniques with promise for the future. We have more over attempted to strike some balance between the different areas of research on neurosecretion so that the volume as a whole may be of interest to the general reader, and that he will find in it a reasonably coherent pattern of thought which demonstrates neurosecretion as the final neuroendocrine pathway. We have attempted a certain degree of uniformity of spelling, symbols, etc.

Neurosecretion and Neuroendocrine Activity

Author: W. Bargmann

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 617

ISBN-13: 3642668852

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This volume on the evolutionary aspects of neuro-endocrinology is based on contributions from the 7th International Symposium on Neurosecretion, which took place in Leningrad, on August 15-21, 1976. The book deals with three major approaches in elucidating the general evolutionary events responsible for the structure and function of neurosecretory elements: (1) phylogenetic development of neurosecretory elements and their function, (2) ontogenetic development of neurosecretory elements and their function, and (3) the role of neuroendocrine mechanisms in realizing species adaptation, i.e., mechanisms causing the evolutionary process. Half of the chapters deal with evolutionary aspects. The majority of them are concerned with the role of different types of neurosecretory cells in the regulation of homeostasis and of the function of endocrine glands, primarily that of the adenohypophysis. The other half are concerned with various aspects of neurosecretion, featuring two main problems: (1) investigation of neural and hormonal mechanisms regulating the function of neurosecretory cells and neurosecretory centers as a whole, and (2) investigation of the role of neurosecretory systems in the regulation of adaptive reactions of the organism.

Neurosecretion

Author: B. Pickering

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 263

ISBN-13: 1468455028

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This volume collects together the Proceedings of the Tenth International Symposium on Neurosecretion which was held in Bristol in September 1987. This series of symposia began with a meeting in Naples in 1953 and it was particularly gratifying to welcome two members of that original gathering, Berta Scharrer and Ellen Thomsen, to the 10th Symposium. The acceptance of the invitation to meet in Bristol gave particular pleasure to the Local Organising Committee because it was the first time that a former venue was revisited - the 3rd Symposium was organised in Bristol by Hans Heller in 1961 and we were very glad that his widow, Josephine, was able to be the Guest-of-Honour at the banquet of our 10th symposium. Neurosecretion has diversified considerably since the first meeting in 1953. From the outset, the local committee decided to focus the meeting by organising it under the title "Cellular aspects of the production and release of neuropeptides. " Having sought advice from the International Committee for Symposia on Neurosecretion, we invited 28 scientists from throughout the world to present their work on aspects ranging from the organisation of the gene through to the electrical properties of peptide-secreting neurones. The progress of studies in neurosecretion owes much to the comparative approach and we attempted to reflect this in the programme of the tenth symposium by inviting the speakers, to illustrate the various aspects of neuropeptide secretion, from among scientists working with systems in many parts of the animal kingdom.

The Peptidergic Neuron

Author: B. Krisch

Publisher: Birkhäuser

Published: 2012-12-06

Total Pages: 358

ISBN-13: 3034890109

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Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system.

Histophysiology of Synapses and Neurosecretion

Author: Eduardo D.P. De Robertis

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 260

ISBN-13: 148318059X

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Histopbysiology of Synapses and Neurosecretion discusses the relationship between subcellular structure and function in synapses. The title discusses how neurosecretion phenomenon takes place in the important areas of central and peripheral nervous system. The first part of text deals with the synapse. Topics such as the concept of synaptic transmission, morphology of synaptic region, and ultrastructure of synaptic region are covered in the first part. Part I also discusses the MORPHO-physiological correlations in certain synapses; and neurochemical studies in isolated nerve endings and synaptic vesicles of the CNS. The second part of the selection covers neorosecretion. Part II tackles the neurohumoral mechanisms and secretion in the hypothalamicneurohypophysial system; secretory processes; and secretion in adrenergic nerves and endings. The book will be of great use to student, researchers, and practitioners of neurology.

Comparative Aspects of Tumor Development

Author: Hans E. Kaiser

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 270

ISBN-13: 9400910916

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Of the interaction and relationship of both systems is chal In this volume, aspects of neoplastic spread, already elu cidated in Volumes I-IV of this series, are considered lenging indeed. against a broad biological background. The mammalian The volume also reviews environmental oncology and species-specific aspects of environmental chain reactions. It orders constituting the logical framework for man as focal point of a comparative oncology are reviewed. Selected is apparent that the environment plays a significant role in examples of neoplastic progression in various taxonomic the development of neoplasms. Neoplasms among the spe units are provided, beginning with the opposite pole of ci es have become much more common as a result of man's taxonomic development, the vascular plants, where no impact on the environment. The latter chapters present a metastatis of malignant neoplasms occur. Among in brief review of geologic and technologic and cuItural vertebrates, vertebrates, and vascular plants, Iining mem changes, and the implications of species-specific cancer pro branes (epithelia) exhibit the highest degree of comparabil gression. The remainder of this section outlines a number of ity. Metastases also occur, but more rarely, in invertebrates; selected chain reactions leading to neoplastic development and are discussed as they are found in the nonmammalian in certain members of these chains. A discussion of the vertebrates: in fish, amphibians, reptiles, and birds. Diseases storage of chemical carcinogens in plants and their interac ofthe leukemia (Ieucosis)-Iymphoma complex are present in tion with other causes of neoplastic growth is also included.