In recent years our approach to neurodevelopmental disorders has undergone extraordinary change. This has resulted from tremendous progress in various different disciplines including developmental neuroscience, behavioural and molecular genetics, and developmental neurobiology, and from the very high quality now achievable in neuroimaging and neurophysiological techniques. This publication aims to provide a concise and interdisciplinary approach to the study of the different cognitive/behavioural phenotypes encountered in a wide range of neurodevelopmental disorders. Starting from methodological, nosographic, and assessment premises, the book deals with selected disorders of a defined but still complex genetic aetiology, and concludes with a description of the neuropsychiatric disorders that are most commonly encountered during development.
Brings together the growing amount of evidence on the assessment and treatment of offenders with intellectual and developmental disabilities. Written by a team of international experts, this comprehensive and informative book provides a contemporary picture of evidence-based practice for offenders with intellectual and developmental disabilities. By adopting a scientist-practitioner position directed at an academic level with practitioner guidelines, it provides a valuable reference source for professionals from allied disciplines who are using or seeking to apply research for this client group. The Wiley Handbook of What Works for Offenders with Intellectual and Developmental Disabilities: An Evidence Based Approach to Theory, Assessment and Treatment is divided into five sections: Introduction, Phenotypes & Genotypes and Offending Behavior, Validated Assessments, Treatment, and Conclusions. The Introduction offers an overview of the entire book and is followed by a second overview covering the ethics of evidence-based practice. After that come chapters on protecting the rights of people with intellectual disabilities in correctional settings, and behavioral and cognitive phenotypes in genetic disorders associated with offending. The third part of the book studies the assessment of individuals with anger and violence issues, inappropriate sexual behavior, alcohol abuse, and emotional difficulties. Next comes a section that looks how to offenders can be treated. The final section discusses future directions and requirements for offenders with intellectual and developmental disabilities. Provides an overview of the ethical challenges and issues faced by those who work with intellectually and developmentally disabled offenders Focuses on proof of treatment effectiveness and validation of assessment methods to direct readers toward "What Works" Features contributions from authors across the entire English-speaking world including the UK, US, Canada, Australia, and New Zealand The Wiley Handbook of What Works for Offenders with Intellectual and Developmental Disabilities: An Evidence Based Approach to Theory, Assessment and Treatment will appeal to all who work in the field of offenders with intellectual and developmental disabilities, including nursing staff, social workers and probation officers, medical and psychology staff, and more.
Increasing interest over recent years in the study of the influences of environment and genetic factors on behavioural disorder has come from a wide range of disciplines. These studies have subsequently been focused through the foundation of the Society for the Study of Behavioural Phenotypes, which forms the basis for assimilating new information and coordinating future research in this field. This volume from founder members of the society presents a distillation of thinking and reviews appropriate measurement schedules. Including research findings, explanation of concepts, genetic scientific techniques and methodological issues, this work will be welcomed by those with an interest in behavioural disorder at every level.
Clinics in Developmental Medicine No. 157 Clinicians, educators and other specialists who work with young people with intellectual disabilities are increasingly aware of the extent to which their clients' behaviours are shaped by the respective causal syndrome. This book is a practical response to the need for interventions and ongoing care programmes to take account of this within the context of coordinated multimodal case planning. An international team of experts drawn from child health, special education, psychology, psychiatry and related disciplines explores general principles of case management, in addition to giving consideration to a large number of individual syndromes, resulting in a comprehensive review of the subject. All of the authors have been involved in original research on the themes explored, and in the development of coherent service responses to the challenges posed by behavioural phenotypes. This will be essential reading for all professionals engaged in the care and management of people with intellectual disabilities.
Highly Commended, BMA Medical Book Awards 2014 Comprehensive and erudite, Forensic Psychiatry: Clinical, Legal and Ethical Issues, Second Edition is a practical guide to the psychiatry of offenders, victims, and survivors of crime. This landmark publication has been completely updated but retains all the features that made the first edition such a well-established text. It integrates the clinical, legal, and ethical aspects of forensic psychiatry with contributions from internationally regarded experts from a range of clinical professions. The Second Edition features updates to all current chapters and several new chapters that explore: The genetics of antisocial behavior Disorders of brain structure and function that relate to crime Offenders with intellectual disabilities Older people and the criminal justice system Deviant and mentally ill staff Although the book focuses on jurisdictions in the UK, a substantial comparative chapter written by an international group from all five continents explores the different philosophies, legal principles, and style of services elsewhere. This book is an essential reference for specialists and postgraduate trainees in forensic psychiatry but also for general psychiatrists, and clinical and forensic psychologists. It is also an invaluable resource for other forensic mental health professionals, including nurses, social workers, occupational therapists, probation service staff, police, attorneys, criminologists, and sociologists.
Neurocutaneous Syndromes unify a group of rare neurological disorders in which the initial identification depends on simple visual disgnosis. They include a large group of neurological disorders which feature cutaneous and ocular lesions, brain malformations, central and peripheral brain tumours, mental retardation, seizures and psychiatric problems. In the last few years, our knowledge of neurocutaneous syndromes has increased substantially. The aim of this volume is to provide an updated developmental perspective on these multifaceted conditions and to review their major clinical features, in particular their embryological basis, clinical molecular genetics, diagnostic protocols and novel therapeutic approaches.
This volume provides updated information on epilepsy genes, on the clinical picture of genetic epilepsies discovered so far, and on conceptual advances in the complicated area of genotype-phenotype correlations. Recent studies on monogenic epilepsies present new insights into mechanisms whereby a mutation of a single gene, coding for an ion channel, can result in a complex epileptic phenotype. The analysis of genetically-determined epileptogenic dysplasia is advancing our understanding of the role of genes in controlling normal and pathological brain development. The pathogenic mechanisms by which gene mutations determine progressive myoclonus epilepsies offer critical opportunities to understand the role of genetic factors in neurodegenerative phenome-na associated with an even broader range of progressive epilepsy types. The specialists who have contributed to this book are outstanding international experts in their respective fields, ensuring first and foremost that the reviews are of relevance to clinicians dealing with epilepsy in their daily practice, as well as providing the highest quality scientific information for biomedical research.
Autism is a complex disorder of neurodevelopment resulting in pervasive abnormalities in social interaction and communication, repetitive behaviours and restricted interests. It presents difficult challenges to physicians and other professionals and especially to the parents and families of affected individuals. The aim of this volume is to provide an update on this multi-faceted condition, and to review most of its major features, in particular its biology, genetics and current understanding of its brain basis. The book emphasises the importance of early detection, and spells out appropriate steps for clinical diagnosis and investigations such as neuropsychology, electrophysiology and imaging. Of particular interest are chapters that focus on differential diagnosis, advances in neurogenetics and molecular biology, possible consequences of immunisations and the relation between autism and epilepsy.