Neurobiology of the Placebo Effect, Part I, Volume 138 in the International Review of Neurobiology series, is the first of two volumes that provide the latest placebo studies in clinically relevant models. Placebo responses effects are not merely a psychological, but a complex psycho-neuro-biological process that requires activation of distinct brain areas. This book discusses current research and projects on the involved brain circuitry and neurotransmitter systems. Specific chapters cover such topics as pharmacological conditioning of the endocrine and immune system, expectancy modulation of opioid neurotransmission, nocebo effects in visceral pain, and conditioning as a higher-order cognitive phenomenon, amongst other topics.
Due to advances within neuroscience, we are now in a much better position to be able to describe and discuss the biological mechanisms that underlie the doctor-patient relationship. Using this knowlege, this book describes and demonstrates the power that the doctor's behaviour has on a patient's behaviour and capacity for recovery from illness.
Neurobiology of the Placebo Effect, Part I, Volume 138 in the International Review of Neurobiology series, is the first of two volumes that provide the latest placebo studies in clinically relevant models. Placebo responses effects are not merely a psychological, but a complex psycho-neuro-biological process that requires activation of distinct brain areas. This book discusses current research and projects on the involved brain circuitry and neurotransmitter systems. Specific chapters cover such topics as pharmacological conditioning of the endocrine and immune system, expectancy modulation of opioid neurotransmission, nocebo effects in visceral pain, and conditioning as a higher-order cognitive phenomenon, amongst other topics. - Latest placebo studies in clinically relevant models - Current research and projects on the involved brain circuitry and neurotransmitter systems - Specific chapters on applications
Neuroscience of Pain, Stress, and Emotion: Psychological and Clinical Implications presents updated research on stress, pain, and emotion, all key research areas within both basic and clinical neuroscience. Improved research understanding of their interaction is ultimately necessary if clinicians and those working in the field of psychosomatic medicine are to alleviate patient suffering. This volume offers broad coverage of that interaction, with chapters written by major researchers in the field. After reviewing the neuroscience of pain and stress, the contents go on to address the interaction between stress and chronic/acute pain, the role of different emotions in pain, neurobiological mechanisms mediating these various interactions, individual differences in both stress and pain, the role of patient expectations during treatment (placebo and nocebo responses), and how those relate to stress modulation. While there are books on the market which discuss pain, stress, and emotion separately, this volume is the first to tackle their nexus, thus appealing to both researchers and clinicians. - Represents the only comprehensive reference detailing the link between pain, stress and emotion, covering the neuroscientific underpinnings, related psychological processes, and clinical implications - Compiles, in one place, research which promises to improve the methodology of clinical trials and the use of knowledge of pain-stress-emotion effects in order to reduce patients' suffering - Provides comprehensive chapters authored by global leaders in the field, the broadest, most expert coverage available
Psychodynamic psychotherapy and psychoanalysis have had to defend themselves from a barrage of criticisms throughout their history. In this book David Jopling argues that the changes achieved through therapy are really just functions of placebos that rally the mind's native healing powers. It is a bold new work that delivers yet another blow to Freud and his followers.
Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics. - Presents the latest information on placebo studies in clinically relevant models - Provides current research and projects on involved brain circuitry and neurotransmitter systems - Contains specific chapters on applications
Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson’s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.
The placebo effect is probably the most striking and well known demonstration of the interaction between psychological and somatic factors. This compendium by leading experts presents the latest findings on this complex psychobiological process. It provides insights into the underlying mechanisms and the neurobiological foundation of the placebo effect and shows how we can now develop principles for clinical application. Specific topics covered include placebo effects on physical performance and influence of verbal suggestions, antidepressant placebo effects, effect of patient involvement in treatment decisions on placebo effects, assessing patient attitudes to and experiences with medication, and transfer of the placebo analgesic effect to anti-itching medication.
This book intends to open the debate between three main aspects of clinical practice: psychotherapy (including psychological and philosophical influences), neurobiology and pharmacology. These three main themes are clinically applied in what we call the “Intervention Triangle”. The book will first focus on epistemologically distinct frameworks and gradually attempt to consider the integration of these three fundamental vertexes of practice. These vertexes are substantially unbalanced in the mental health field, and thus, this book tries to make sense of this phenomenon. Unique in its interdisciplinary and comprehensive view of mental health problems and approaches, this book offers a new perspective on unidisciplinary integration that previous publications have not considered. As an innovative contribution to its field, this volume will be particularly relevant to practitioners working towards integrative frameworks. It will also be of interest to students, clinicians and researchers, in particular, those working in psychology, medicine, psychiatry, philosophy, social work, and pharmacy.
