Drug Delivery with Targeted Nanoparticles

Drug Delivery with Targeted Nanoparticles

Author: Yılmaz Çapan

Publisher: CRC Press

Published: 2021-11-30

Total Pages: 654

ISBN-13: 1000375307

DOWNLOAD EBOOK

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.


Nanoparticles for Drug Delivery

Nanoparticles for Drug Delivery

Author: K. S. Joshy

Publisher: Springer Nature

Published: 2021-06-21

Total Pages: 214

ISBN-13: 9811621195

DOWNLOAD EBOOK

This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.


Modeling and Control of Drug Delivery Systems

Modeling and Control of Drug Delivery Systems

Author: Ahmad Taher Azar

Publisher: Academic Press

Published: 2021-02-06

Total Pages: 410

ISBN-13: 0128211954

DOWNLOAD EBOOK

Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS


Advances in Nanotechnology-Based Drug Delivery Systems

Advances in Nanotechnology-Based Drug Delivery Systems

Author: Anupam Das Talukdar

Publisher: Elsevier

Published: 2022-06-06

Total Pages: 672

ISBN-13: 0323904149

DOWNLOAD EBOOK

Advances in Nanotechnology-Based Drug Delivery Systems covers the core concepts and latest research regarding the use of nanoscale materials for the development and application of drug delivery systems. The book introduces the reader to nanotechnology in drug delivery, covering the synthesis, encapsulation techniques, characterization and key properties of nanoscale drug delivery systems. Later chapters review the broad range of target applications, including site-specific delivery of drugs for cardiovascular disease, cancer, bacterial infection, bone regeneration. and much more. This book helps translate advanced research into a clinical setting, analyzing the toxicity and health and safety challenges associated with utilizing nanotechnology in biomedicine. This will be a useful reference for those interested in nano-sized drug delivery in biomedicine, including academics and researchers in materials science, biomedical engineering, pharmaceutical science and related disciplines. Provides a clear introduction to nanotechnology in drug delivery, covering key principles, synthesis, characterization and unique properties of nanoscale materials for drug delivery systems“/li> Discusses preclinical, clinical and patented nano-drug delivery systems, enabling the reader to grasp the current state-of-the-art and market Covers a broad range of targets for nanoscale drug delivery systems, such as in neurological disorders, oral disease, renal disease, cancer, skin protection, and much more


Handbook of Nanoencapsulation

Handbook of Nanoencapsulation

Author: Jasmeet Kour

Publisher: CRC Press

Published: 2023-04-05

Total Pages: 392

ISBN-13: 1000834107

DOWNLOAD EBOOK

Nutraceutical encapsulation envelopes protection of products from oxidative damage, controlled delivery of nanoencapsulated nutraceuticals and improved nutraceutical bioavailability as well as biological action. It is a promising technique to ensure the stabilization of such labile compounds and to protect the core ingredients from premature reactions and interactions In a comprehensive manner, the Handbook of Nanoencapsulation: Preparation, Characterization, Delivery and Safety of Nutraceutical Nanocomposites presents various nanosystems/nanocarriers, physical and chemical techniques used in encapsulation of various nutraceuticals, and the targeted delivery of various significant nutraceuticals. This book bridges the gap between academia and research as it encompasses the ubiquitous applications of nanoencapsulation technique used on significant nutraceuticals derived from plants, animals as well as microalgae. Key Features: Provides a quick and easy access to major plant, animal and microalgae derived nutraceutical ingredients Discusses nanoencapsulation techniques for protection and targeted release of various food bioactive ingredients. Covers safety, bioaccessibility and multiple applications of nanoencapsulated nutraceuticals in the food industry Unveiling pivotal aspects of nanoencapsulation of significant nutraceuticals, this book is a valuable resource for researchers, food toxicologists, food scientists, nutritionists, and scientists in medicinal research.


Nanocarriers for Drug Delivery

Nanocarriers for Drug Delivery

Author: Josimar O. Eloy

Publisher: Springer Nature

Published: 2021

Total Pages: 347

ISBN-13: 3030633896

DOWNLOAD EBOOK

This book covers basic aspects of different nanoparticles, including type of materials, lipid, polymeric and inorganic structures, synthesis strategies, as well as the main physicochemical characterization techniques. Moreover, this book addresses applications for both treatment and diagnosis of diseases, highlighting in vitro and in vivo findings and clinical evaluation. The chapters highlight the main barriers for drug delivery which can benefit from nanoencapsulation: the topical and oral routes. The main innovations in the field, such as gene therapy and functionalization of nanoparticles with a variety of moieties, including monoclonal antibodies for selective delivery, are discussed and illustrated with examples. Finally, the application of nanoparticles for drug delivery to cancer is reviewed considering toxicology and regulatory aspects.


Drug Delivery Using Nanomaterials

Drug Delivery Using Nanomaterials

Author: Yasser Shahzad

Publisher: CRC Press

Published: 2022-01-18

Total Pages: 360

ISBN-13: 1000529495

DOWNLOAD EBOOK

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.


Nanopharmaceutical Advanced Delivery Systems

Nanopharmaceutical Advanced Delivery Systems

Author: Vivek Dave

Publisher: John Wiley & Sons

Published: 2020-12-29

Total Pages: 467

ISBN-13: 1119711681

DOWNLOAD EBOOK

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.


Drug Delivery Approaches and Nanosystems, Volume 2

Drug Delivery Approaches and Nanosystems, Volume 2

Author: Raj K. Keservani

Publisher: CRC Press

Published: 2017-11-15

Total Pages: 248

ISBN-13: 1351846663

DOWNLOAD EBOOK

This volume is a thorough presentation of the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. The second of this two-volume set, it addresses the applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. This volume includes 11 chapters that focus on the targeting facet of drug delivery systems. Targeting is a focused maneuver to achieve the specified goals, including achieving the desired result and reaching the specific location. Targeting has now been successfully achieved for several diseases/disorders; however, its role is noteworthy in cancer treatment where chemotherapy is a main course of approach. Nanotechnology-based products have great potential by virtue of their inherent features. This edited book provides a detailed application of nanotechnology in drug delivery systems in health care. The book discusses general principles of drug targeting, material of construction and technological concerns of nanoparticles, and different drug delivery systems and their preparation. Taken together, the informative chapters will provide researchers and scientists as well as faculty and students with valuable research on the effective use of new approaches in advanced drug delivery nanosystems. Volume 1 of the two-volume series is subtitled Novel Drug Carriers. The volumes are available separately or as a set.