Myocardial Ischemia: Mechanisms, Reperfusion, Protection
Myocardial Ischemia: Mechanisms, Reperfusion, Protection

Author: Morris Karmazyn

Publisher: Springer Science & Business Media

Published: 1996-08-28

Total Pages: 538

ISBN-13: 9783764352691

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Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.

Mechanisms of Vascular Disease
Mechanisms of Vascular Disease

Author: Robert Fitridge

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 589

ISBN-13: 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Myocardial Protection
Myocardial Protection

Author: Tomas A. Salerno

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 344

ISBN-13: 1405178434

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Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Myocardial Ischemia: Mechanisms, Reperfusion, Protection
Myocardial Ischemia: Mechanisms, Reperfusion, Protection

Author: Morris Karmazyn

Publisher: Birkhäuser

Published: 2013-03-12

Total Pages: 508

ISBN-13: 3034889887

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Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.

Coronary Microvascular Obstruction in Acute Myocardial Infarction
Coronary Microvascular Obstruction in Acute Myocardial Infarction

Author: Giampaolo Niccoli

Publisher: Academic Press

Published: 2018-07-07

Total Pages: 401

ISBN-13: 0128133619

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Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO. - Provides in-depth coverage of coronary microvascular obstruction (CMVO), spanning research, management, prevention and treatment - Includes the most up-to-date information on CMVO as presented from top experts around the word - Provides access to a companion website with extra material, including tables, additional references and instructional videos - Gives extensive coverage on how to measure CMVO, including in-depth indexes that can be used to detect and quantify the phenomenon

Cardioprotection
Cardioprotection

Author: Derek Hausenloy

Publisher: Oxford University Press

Published: 2009-08-20

Total Pages: 138

ISBN-13: 019954476X

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Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.

Ischaemia-Reperfusion Injury
Ischaemia-Reperfusion Injury

Author: Pierce A. Grace

Publisher: Wiley-Blackwell

Published: 1999-02-04

Total Pages: 400

ISBN-13: 9780632050215

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Ischaemia-Reperfusion Injury is concerned with the consequences of interrupting and restoring blood flow to tissues. Many common clinical conditions are caused by interruption of blood flow to tissues (eg, ischaemic heart disease, peripheral vascular disease, stroke); blood flow is also interrupted deliberately in many surgical procedures (eg, cardiac surgery, arterial surgery, transplant surgery, limb surgery with tourniquet). In treating such conditions or after performing such operations the aim of the clinician is to restore the blood supply to the ischaemic tissue. Paradoxically, restoration of blood flow to ischaemic tissues can lead to further tissue damage with the potential for severe local and systemic injury. This book focuses on the clinical, pathological and biochemical processes involved in ischaemia-reperfusion injury and gives an overview of the strategies that may be adopted to mitigate or prevent such injury. This book will be of interest to both clinicians and scientists who have to deal with or have interest in this difficult but important problem.

Oxidative Stress in Heart Diseases
Oxidative Stress in Heart Diseases

Author: Sajal Chakraborti

Publisher: Springer Nature

Published: 2019-11-06

Total Pages: 589

ISBN-13: 9811382735

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This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

Cardiovascular Disability
Cardiovascular Disability

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2010-12-04

Total Pages: 304

ISBN-13: 030915698X

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The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.

Handbook of Cardiac Anatomy, Physiology, and Devices
Handbook of Cardiac Anatomy, Physiology, and Devices

Author: Paul A. Iaizzo

Publisher: Springer

Published: 2015-11-13

Total Pages: 806

ISBN-13: 331919464X

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This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.