Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation
Author: Jerome Noailly
Publisher: Frontiers Media SA
Published: 2022-03-11
Total Pages: 317
ISBN-13: 2889746623
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Multiscale Cancer Modeling
Author: Thomas S. Deisboeck
Publisher: CRC Press
Published: 2010-12-08
Total Pages: 492
ISBN-13: 1439814422
DOWNLOAD EBOOKCancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Multiscale Modeling of Cancer
Author: Vittorio Cristini
Publisher: Cambridge University Press
Published: 2010-09-09
Total Pages: 299
ISBN-13: 1139491504
DOWNLOAD EBOOKMathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
Practical Aspects of Computational Chemistry
Author: Jerzy Leszczynski
Publisher: Springer Science & Business Media
Published: 2009-10-03
Total Pages: 468
ISBN-13: 9048126878
DOWNLOAD EBOOK"Practical Aspects of Computational Chemistry" presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds, carbon nanotubes and hydrogen storage, adsorption and decomposition of organophosphorus compounds, X-ray crystallography, proton transfer, structure-activity relationships, a description of the REACH programs of the European Union for chemical regulatory purposes, reactions of nucleic acid bases with endogenous and exogenous reactive oxygen species and different aspects of nucleic acid bases, base pairs and base tetrads.
Multiscale Modeling and Simulation of Composite Materials and Structures
Author: Young Kwon
Publisher: Springer Science & Business Media
Published: 2007-12-04
Total Pages: 634
ISBN-13: 0387363181
DOWNLOAD EBOOKThis book presents the state-of-the-art in multiscale modeling and simulation techniques for composite materials and structures. It focuses on the structural and functional properties of engineering composites and the sustainable high performance of components and structures. The multiscale techniques can be also applied to nanocomposites which are important application areas in nanotechnology. There are few books available on this topic.
Mechanobiology
Author: Glen L. Niebur
Publisher: Elsevier
Published: 2019-12-01
Total Pages: 256
ISBN-13: 0128179325
DOWNLOAD EBOOKMechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena
Dexterity and Its Development
Author: Nicholai A. Bernstein
Publisher: Psychology Press
Published: 2014-04-04
Total Pages: 587
ISBN-13: 1135693226
DOWNLOAD EBOOKThis is a very unusual book. It brings to the English speaking reader a masterpiece written some 50 years ago by one of the greatest minds of the 20th century--Nicholai Aleksandrovich Bernstein--considered the founder of many contemporary fields of science such as biomechanics, motor control, and physiology of activity. Divided into two parts, this volume's first section is a translation of the Russian book On Dexterity and Its Development. It presents, in a very reader-friendly style, Bernstein's major ideas related to the development and control of voluntary movements in general, and to the notion of dexterity, in particular. Although very few scientific works remain interesting to the reader 50 years after they were written, this volume--now available for the first time in English--is a rare exception to this rule. His ideas are certainly not obsolete. Actually, we are just starting to grasp the depth and breadth of his thinking, especially his analysis of the complex notion of dexterity. The second section provides both a historical and a contemporary perspective on Bernstein's ideas. The original work was directed at a wide audience ranging from specialists in biomechanics and motor behavior, to coaches, neurologists, physical therapists, athletes, and even inquisitive college and high school students. The chapters contributed by contemporary scientists mirror Bernstein's style and present new findings in the areas of biomechanics, motor control, and motor development in a way that would be both understandable to non-specialists in these areas, and informative for professionals working in different areas related to human movement. All those interested in the origins and mechanisms of the production of voluntary movements, irrespective of their educational and professional background, will find this book valuable. In addition, the unique history and composition of this text will make it helpful and attractive to historians and philosophers of science.
Feedback Systems
Author: Karl Johan Åström
Publisher: Princeton University Press
Published: 2021-02-02
Total Pages:
ISBN-13: 069121347X
DOWNLOAD EBOOKThe essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory
Cardiovascular Solid Mechanics
Author: Jay D. Humphrey
Publisher: Springer Science & Business Media
Published: 2013-06-29
Total Pages: 766
ISBN-13: 038721576X
DOWNLOAD EBOOKThis text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.
Computer Methods in Biomechanics and Biomedical Engineering
Author: J. Middleton
Publisher: CRC Press
Published: 1996-03-18
Total Pages: 582
ISBN-13: 9782919875009
DOWNLOAD EBOOKThese papers are concerned with new advances and novel solutions in the areas of biofluids, image-guided surgery, tissue engineering and cardovascular mechanics, implant analysis, soft tissue mechanics, bone remodeling and motion analysis. The contents also feature a special section on dental materials, dental adhesives and orthodontic mechanics. This edition contains many examples, tables and figures, and together with the many references, provides the reader with invaluable information on the latest theoretical developments and applications.
