Based around recent lectures given at the prestigious Ritsumeikan conference, the tutorial and expository articles contained in this volume are an essential guide for practitioners and graduates alike who use stochastic calculus in finance. Among the eminent contributors are Paul Malliavin and Shinzo Watanabe, pioneers of Malliavin Calculus. The coverage also includes a valuable review of current research on credit risks in a mathematically sophisticated way contrasting with existing economics-oriented articles.
This book covers important aspects of modern optical microscopy and image restoration technologies. Instead of pure optical treatment, the book is delivered with the consideration of the scientists who utilize optical microscopy in their daily research. However, enough details are provided in basic imaging principles, optics and instrumentation in microscopy, spherical aberrations, deconvolution and image restoration. A number of microscopic technologies such as polarization, confocal and multi-photon microscopy are highlighted with their applications in biological and materials sciences/engineering.
There is an urgent need to develop and integrate new statistical, mathematical, visualization, and computational models with the ability to analyze Big Data in order to retrieve useful information to aid clinicians in accurately diagnosing and treating patients. The main focus of this book is to review and summarize state-of-the-art big data and deep learning approaches to analyze and integrate multiple data types for the creation of a decision matrix to aid clinicians in the early diagnosis and identification of high risk patients for human diseases and disorders. Leading researchers will contribute original research book chapters analyzing efforts to solve these important problems.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Fast-emerging optical imaging and data fusion techniques are creating a huge buzz as potentially powerful tools for cancer detection and other important clinical applications. Heres the first comprehensive resource on multimodal optical imaging. This unique book gives biomedical researchers the full details on in-vivo microscopy, optical coherence tomography, endoscopy, and diffuse optical techniques. It explains how these tools can be integrated with other modalities to capture and apply biological information in significant new ways. Written by pioneers in the field, this milestone work discusses each of the optical imaging techniques in depth and describes the integration of the techniques with other modalities like MRI, X-Ray imaging, and PET imaging. The volume also covers photodynamic therapy and molecular imaging, and reviews clinical studies in optical imaging and other issues. DVD Included! Contains full-color images and videos that support key topics covered in the book.
Brings a fresh point of view to the current state of correlative imaging and the future of the field This book provides contributions from international experts on correlative imaging, describing their vision of future developments in the field based on where it is today. Starting with a brief historical overview of how the field evolved, it presents the latest developments in microscopy that facilitate the correlative workflow. It also discusses the need for an ideal correlative probe, applications in proteomic and elemental analysis, interpretation methods, and how correlative imaging can incorporate force microscopy, soft x-ray tomography, and volume electron microscopy techniques. Work on placing individual molecules within cells is also featured. Correlative Imaging: Focusing on the Future offers in-depth chapters on: correlative imaging from an LM perspective; the importance of sample processing for correlative imaging; correlative light and volume EM; correlation with scanning probe microscopies; and integrated microscopy. It looks at: cryo-correlative microscopy; correlative cryo soft X-ray imaging; and array tomography. Hydrated-state correlative imaging in vacuo, correlating data from different imaging modalities, and big data in correlative imaging are also considered. Brings a fresh view to one of the hottest topics within the imaging community: the correlative imaging field Discusses current research and offers expert thoughts on the field’s future developments Presented by internationally-recognized editors and contributors with extensive experience in research and applications Of interest to scientists working in the fields of imaging, structural biology, cell biology, developmental biology, neurobiology, cancer biology, infection and immunity, biomaterials and biomedicine Part of the Wiley–Royal Microscopical Society series Correlative Imaging: Focusing on the Future will appeal to those working in the expanding field of the biosciences, correlative microscopy and related microscopic areas. It will also benefit graduate students working in microscopy, as well as anyone working in the microscopy imaging field in biomedical research.
This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.
Stroke is one of the leading causes of death in the world, resulting mostly from the sudden ruptures of atherosclerosis carotid plaques. Understanding why and how plaque develops and ruptures requires a multi-disciplinary approach such as radiology, biomedical engineering, medical physics, software engineering, hardware engineering, pathological and histological imaging. Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment presents a new dimension of understanding Atherosclerosis in 2D and 3D. This book presents work on plaque stress analysis in order to provide a general framework of computational modeling with atherosclerosis plaques. New algorithms based on 3D and 4D Ultrasound are presented to assess the atherosclerotic disease as well as very recent advances in plaque multimodality image fusion analysis. The goal of Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment is to fuse information obtained from different 3D medical image modalities, such as 3D US, CT and MRI, providing the medical doctor with some sort of augmented reality information about the atherosclerotic plaque in order to improve the accuracy of the diagnosis. Analysis of the plaque dynamics along the cardiac cycle is also a valuable indicator for plaque instability assessment and therefore for risk stratification. 4D Ultrasound, a sequence of 3D reconstructions of the region of interest along the time, can be used for this dynamic analysis. Multimodality Image Fusion is a very appealing approach because it puts together the best characteristics of each modality, such as, the high temporal resolution of US and the high spatial resolutions of MRI and CT.
This book provides a state-of-the-art overview of the combined use of imaging modalities to obtain important functional and morphological information on intravascular disease and enhance disease detection. It discusses the integration of intravascular ultrasound (IVUS, intravascular optical coherence tomography (OCT), intravascular photoacoustic imaging (IVPA) and acoustic radiation force optical coherence elastography (ARF-OCE), and introduces the integration of multimodality imaging systems, such as IR and florescence. It includes the latest research advances and numerous imaging photos to offer readers insights into current intravascular applications. It is a valuable resource for students, scientists and physicians wanting to gain a deeper understanding of multimodality imaging tools.
This book constitutes the refereed joint proceedings of the 4th International Workshop on Deep Learning in Medical Image Analysis, DLMIA 2018, and the 8th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 39 full papers presented at DLMIA 2018 and the 4 full papers presented at ML-CDS 2018 were carefully reviewed and selected from 85 submissions to DLMIA and 6 submissions to ML-CDS. The DLMIA papers focus on the design and use of deep learning methods in medical imaging. The ML-CDS papers discuss new techniques of multimodal mining/retrieval and their use in clinical decision support.
