Structural Bioinformatics
Structural Bioinformatics

Author: Jenny Gu

Publisher: John Wiley & Sons

Published: 2009-03-16

Total Pages: 1108

ISBN-13: 0470181052

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Structural Bioinformatics was the first major effort to show the application of the principles and basic knowledge of the larger field of bioinformatics to questions focusing on macromolecular structure, such as the prediction of protein structure and how proteins carry out cellular functions, and how the application of bioinformatics to these life science issues can improve healthcare by accelerating drug discovery and development. Designed primarily as a reference, the first edition nevertheless saw widespread use as a textbook in graduate and undergraduate university courses dealing with the theories and associated algorithms, resources, and tools used in the analysis, prediction, and theoretical underpinnings of DNA, RNA, and proteins. This new edition contains not only thorough updates of the advances in structural bioinformatics since publication of the first edition, but also features eleven new chapters dealing with frontier areas of high scientific impact, including: sampling and search techniques; use of mass spectrometry; genome functional annotation; and much more. Offering detailed coverage for practitioners while remaining accessible to the novice, Structural Bioinformatics, Second Edition is a valuable resource and an excellent textbook for a range of readers in the bioinformatics and advanced biology fields. Praise for the previous edition: "This book is a gold mine of fundamental and practical information in an area not previously well represented in book form." —Biochemistry and Molecular Education "... destined to become a classic reference work for workers at all levels in structural bioinformatics...recommended with great enthusiasm for educators, researchers, and graduate students." —BAMBED "...a useful and timely summary of a rapidly expanding field." —Nature Structural Biology "...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." —Briefings in Bioinformatics

Grant's Dissector
Grant's Dissector

Author: Alan J. Detton

Publisher: LWW

Published: 2020-03-14

Total Pages: 0

ISBN-13: 9781975134600

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Grant's Dissector provides step-by-step human cadaver dissection procedures for students to perform in the anatomy lab and to recognize important relationships revealed through dissection. More informative and approachable than ever, this updated seventeenth edition broadens students' understanding of key dissection procedures and readies them for success in healthcare practice. Each chapter is consistently organized beginning with a Dissection Overview that provides a blueprint of what needs to be accomplished during the dissection session and includes relevant surface anatomy. Dissection Instructions offer a logical sequence and numbered steps for the dissection. The Dissection Follow-up emphasizes important features of the dissection and encourages students to reflect on and synthesize the information. New and revised illustrations, including new surface landmark illustrations, strengthen students' grasp of common dissection procedures. New chapter introductions focus students' attention on relevant Clinical Correlations. Reorganized Skeletal and Surface Anatomy sections guide students logically from palpating bony structures to making skin incisions. Enhanced and streamlined cross-references reinforce understanding with direct links to related content in Grant's Atlas of Anatomy as well as Grant's Dissection Videos. Dissection Overviews guide students through relevant surface anatomy and osteology. Numbered, step-by-step Dissection Instructions clarify procedures and enhance the dissection experience. Full-color illustrations improve students' accuracy and precision from initial incisions through deeper dissections. Clinical Correlation boxes place procedures in a clinical context to ready students for healthcare practice. eBook available for purchase. Fast, smart, and convenient, today's eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more

Bioinformatics for Beginners
Bioinformatics for Beginners

Author: Supratim Choudhuri

Publisher: Elsevier

Published: 2014-05-09

Total Pages: 238

ISBN-13: 0124105106

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Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration

Finding What Works in Health Care
Finding What Works in Health Care

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2011-07-20

Total Pages: 267

ISBN-13: 0309164257

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Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.

Re-Imagining Doctoral Writing
Re-Imagining Doctoral Writing

Author: Cecile Badenhorst

Publisher: CSU Open Press

Published: 2021

Total Pages: 292

ISBN-13: 9781646422715

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"Re-imagining Doctoral Writing explores doctoral writing within a context where doctoral education is undergoing enormous transformation. Despite the importance attributed to doctoral writing for developing scholars, we have a limited understanding of the extent to which conceptualizations of doctoral writing are shared or contested, how ideas of doctoral writing have shifted over time, or where imaginings of the future of doctoral writing might take us. Drawing on historical studies that show how understandings of doctoral writing and doctoral writers have changed over time-as well as considering how doctoral writing has changed as we have moved into the 21st century-the contributors to this volume pursue these areas and explore what might happen if we begin thinking about doctoral writing without imagining a vast absence in front of us. By proceeding from a place in which doctoral writing is seen as a rich and increasingly deep area of scholarship, this book offers tools and approaches that expand and enliven conceptions of what doctoral writing might become and how it might be researched"--