The Prince of Las Vegas

The Prince of Las Vegas

Author: Brian Malanaphy

Publisher:

Published: 2017-04-26

Total Pages: 394

ISBN-13: 9780692734339

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A modern retelling of Hamlet, except with a few twists. It's seventies Vegas. Amid the glitz, neon lights, poker players, and flood of cash, Jack Romano, a well-respected self-made casino owner and patriarch, has died. His only son, Nick, arrives home for the funeral and discovers that the death may not have been so accidental. Now he must decide what to do about Claudio, an ambitious, seasoned mobster who is also his dad's so-called business partner. Complications arise as Nick finds himself falling in love with Rosalie, the daughter of one of Claudio's crew. Nick must not only save his family's casino business, but also his dad's hoard of silver, amassed over decades, and stashed in the casino's basement vaults. "The only thing missing are the cement shoes. Malanaphy's tumultuous and thrilling ride through the wise-guy back rooms of not-so-old Las Vegas is a sometimes funny, sometimes not, but always captivating whodunnit that'll keep you turning the pages. The Prince of Las Vegas has it all: Romance, mystery and a fresh take on a Cosa Nostra-esque underworld where behind every poker table there's a mobster looking to grab the great, late Jack Romano's loot. If you can't read this well-honed mobster thriller without cheering on the good guys and boo-hissing the bad ones, well ... fuhgeddaboudit!" - Andy Scontras, author of When You Are Strange "A well written, nostalgic and fun, Vegas crime thriller. Malanaphy's novel does not disappoint!" - Gary Braver, author of Tunnel Vision "Would make a great Scorsese or Tarantino movie." - Douglas Corleone, author of Good As Gone.


The History of the Order of the Eastern Star

The History of the Order of the Eastern Star

Author: Willis Darwin 1846- Engle

Publisher: Legare Street Press

Published: 2022-10-27

Total Pages: 0

ISBN-13: 9781016450256

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Handbook of Drug-Nutrient Interactions

Handbook of Drug-Nutrient Interactions

Author: Joseph I. Boullata

Publisher: Springer Science & Business Media

Published: 2010-03-17

Total Pages: 823

ISBN-13: 160327362X

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Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.


Report of the President to the Board of Directors of the World's Columbian Exposition

Report of the President to the Board of Directors of the World's Columbian Exposition

Author: Harlow Niles Higinbotham

Publisher: Legare Street Press

Published: 2022-10-27

Total Pages: 0

ISBN-13: 9781016156158

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Antibody-Drug Conjugates

Antibody-Drug Conjugates

Author: Jeffrey Wang

Publisher: Springer

Published: 2015-03-05

Total Pages: 248

ISBN-13: 3319130811

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This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field.


Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Author: William Figg

Publisher: Humana Press

Published: 2004-03-26

Total Pages: 623

ISBN-13: 9781588291776

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Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.