Lipid Domains
Lipid Domains

Author:

Publisher: Academic Press

Published: 2015-06-08

Total Pages: 393

ISBN-13: 0128033274

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Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. - Written by leading experts - Contains original material, both textual and illustrative, that should become a very relevant reference material - The material is presented in a very comprehensive manner - Both researchers in the field and general readers should find relevant and up-to-date information

Structure and Dynamics of Membranes
Structure and Dynamics of Membranes

Author: R. Lipowsky

Publisher: Elsevier

Published: 1995-06-15

Total Pages: 537

ISBN-13: 0080541917

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The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Thermal Biophysics of Membranes
Thermal Biophysics of Membranes

Author: Thomas Heimburg

Publisher: John Wiley & Sons

Published: 2008-02-08

Total Pages: 378

ISBN-13: 3527611606

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An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.

An Introduction to Statistical Thermodynamics
An Introduction to Statistical Thermodynamics

Author: Terrell L. Hill

Publisher: Courier Corporation

Published: 2012-06-08

Total Pages: 546

ISBN-13: 0486130908

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Four-part treatment covers principles of quantum statistical mechanics, systems composed of independent molecules or other independent subsystems, and systems of interacting molecules, concluding with a consideration of quantum statistics.

Experimental Approaches of NMR Spectroscopy
Experimental Approaches of NMR Spectroscopy

Author: The Nuclear Magnetic Resonance Society of Japan

Publisher: Springer

Published: 2017-11-23

Total Pages: 634

ISBN-13: 9811059667

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This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

The Structure and Conformation of Amphiphilic Membranes
The Structure and Conformation of Amphiphilic Membranes

Author: Reinhard Lipowsky

Publisher: Springer Science & Business Media

Published: 2013-03-08

Total Pages: 307

ISBN-13: 3642847633

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Membranes composed of amphiphilic molecules are highly flexible surfaces that determine the architecture of biological systems and provide a basic structural element for complex fluids such as microemulsions. Recently, a variety of new experimental methods such as X-ray scattering, neutron scattering, and atomic force microscopy have been used in order to study themolecular structure of these membranes. Their conformational behavior, on the other hand, is studied by optical and electron microscopy, which reveals that membranes in aqueous solution exhibit an amazing variety of different shapes. Several theoretical concepts are described suchas bending elasticity, curvature, and minimal surfaces in order to understand this polymorphism. These concepts are also useful to describe the behavior of membranes in complex fluids where they can build up hexagonal, lamellar, triply-periodic, cubic, and sponge phases. The contributions to this volume provide an up-to-date overview and describe thestate-of-the-art of this rapidly evolving field of research.

Principles of Nuclear Magnetic Resonance Microscopy
Principles of Nuclear Magnetic Resonance Microscopy

Author: Paul T. Callaghan

Publisher:

Published: 1993

Total Pages: 520

ISBN-13: 9780198539971

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Although nuclear magnetic resonance is perhaps best known for its spectacular utility in medical tomography, its potential applicability to fields such as biology, materials science, and chemical physics is being increasingly recognized as laboratory NMR spectrometers are adapted to enable small scale imaging. This excellent introduction to the subject explores principles and common themes underlying two key variants of NMR microscopy, and provides many examples of their use. Methods discussed are not only important to fundamental biological and physical research, but have applications to a wide variety of industries, including those concerned with petrochemicals, polymers, biotechnology, food processing, and natural product processing. The wide range of scientists interested in NMR microscopy will want to own a copy of this book.

Free Energy Calculations
Free Energy Calculations

Author: Christophe Chipot

Publisher: Springer Science & Business Media

Published: 2007-01-08

Total Pages: 528

ISBN-13: 3540384472

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Free energy constitutes the most important thermodynamic quantity to understand how chemical species recognize each other, associate or react. Examples of problems in which knowledge of the underlying free energy behaviour is required, include conformational equilibria and molecular association, partitioning between immiscible liquids, receptor-drug interaction, protein-protein and protein-DNA association, and protein stability. This volume sets out to present a coherent and comprehensive account of the concepts that underlie different approaches devised for the determination of free energies. The reader will gain the necessary insight into the theoretical and computational foundations of the subject and will be presented with relevant applications from molecular-level modelling and simulations of chemical and biological systems. Both formally accurate and approximate methods are covered using both classical and quantum mechanical descriptions. A central theme of the book is that the wide variety of free energy calculation techniques available today can be understood as different implementations of a few basic principles. The book is aimed at a broad readership of graduate students and researchers having a background in chemistry, physics, engineering and physical biology.

Life - As a Matter of Fat
Life - As a Matter of Fat

Author: Ole G. Mouritsen

Publisher: Springer Science & Business Media

Published: 2005-10-24

Total Pages: 273

ISBN-13: 3540270760

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Presents a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. Emphasizes the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Shows how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.

Lipid Bilayers
Lipid Bilayers

Author: J. Katsaras

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 304

ISBN-13: 366204496X

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Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.