Molecularly Imprinted Polymers as Advanced Drug Delivery Systems
Molecularly Imprinted Polymers as Advanced Drug Delivery Systems

Author: Zhaosheng Liu

Publisher: Springer Nature

Published: 2021-04-23

Total Pages: 218

ISBN-13: 9811602271

DOWNLOAD EBOOK

This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Molecularly Imprinted Polymer Composites
Molecularly Imprinted Polymer Composites

Author: Sooraj M.P.

Publisher: Woodhead Publishing

Published: 2020-12-01

Total Pages: 442

ISBN-13: 0128203854

DOWNLOAD EBOOK

Molecular Imprinted Polymer Composites: Synthesis, Characterisation and Applications covers the design of composite materials containing nanostructures and molecular imprinted polymers that has materialized the ever-sought out vision of homogeneous molecular imprinted polymers. The inherent high surface-to-volume ratio of nanostructures has served well in increasing the surface area of conventional bulk polymers. In recent decades, molecularly imprinted polymer nanocomposite materials have attracted much attention for their potential applications in the fields of separation science, sensing, drug delivery, waste water treatment and catalysis, hence this book provides a much needed update on progress. - Includes information on molecular imprinted polymer composites and their potential for commercialization - Discusses their synthesis, characterization and applications - Analyzes the effect of incorporation of different nanostructures on the thermodynamic, kinetic and adsorption behavior of imprinted sorbents

Drug Delivery Systems in Cancer Therapy
Drug Delivery Systems in Cancer Therapy

Author: Dennis M. Brown

Publisher: Humana Press

Published: 2010-11-19

Total Pages: 0

ISBN-13: 9781617372384

DOWNLOAD EBOOK

Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Chemoresponsive Materials
Chemoresponsive Materials

Author: Hans-Jorg Schneider

Publisher: Royal Society of Chemistry

Published: 2015-06-26

Total Pages: 556

ISBN-13: 178262242X

DOWNLOAD EBOOK

Smart materials stimulated by chemical or biological signals are of interest for their many applications including drug delivery, as well as in new sensors and actuators for environmental monitoring, process and food control, and medicine. In contrast to other books on responsive materials, this volume concentrates on materials which are stimulated by chemical or biological signals. Chemoresponsive Materials introduces the area with chapters covering different responsive material systems including hydrogels, organogels, membranes, thin layers, polymer brushes, chemomechanical and imprinted polymers, nanomaterials, silica particles, as well as carbohydrate- and bio-based systems. Many promising applications are highlighted, with an emphasis on drug delivery, sensors and actuators. With contributions from internationally known experts, the book will appeal to graduate students and researchers in academia, healthcare and industry interested in functional materials and their applications.

Mip Synthesis, Characteristics and Analytical Application
Mip Synthesis, Characteristics and Analytical Application

Author:

Publisher: Elsevier

Published: 2019-08-09

Total Pages: 394

ISBN-13: 0444642676

DOWNLOAD EBOOK

Mip Synthesis, Characteristics and Analytical Application, Volume 86 in the Comprehensive Analytical Chemistry series, highlights advances in the field, with this new volume presenting interesting chapters on synthesis and polymerization techniques of molecularly imprinted polymers, Solid phase extraction technique as a general field of application of molecularly imprinted polymer materials, Advanced artificially receptor- based sorbents for solid phase extraction using molecular imprinting technology: a new trend in food analysis, Application of molecularly imprinted polymers in microextraction and solventless extraction techniques, Magnetic molecularly imprinted microspheres – analytical approach, Surface Imprinted Micro- and Nanoparticles, and much more. - Contains a valuable source of information on the wide spectrum of application fields of molecularly imprinted polymers as a green sorption medium - Describes the application potential of currently molecular imprinting technologies, associated with the solid phase extraction techniques, magnetic imprinted microspheres, sorbents in mass spectrometry, and imprinted polymer electrochemical sensors

Switchable Bioelectronics
Switchable Bioelectronics

Author: Onur Parlak

Publisher: CRC Press

Published: 2020-04-21

Total Pages: 209

ISBN-13: 1000092216

DOWNLOAD EBOOK

This book reviews the rapidly emerging field of switchable interfaces and its implications for bioelectronics. The authors piece together early breakthroughs and key developments and highlight the future of switchable bioelectronics by focusing on bioelectrochemical processes based on mimicking and controlling biological environments with external stimuli as well as responsive systems for drug delivery. All chapters in the book strive to answer the fundamental question: How do living systems probe and respond to their surroundings? Following on from that, how can one transform these concepts to serve the practical world of bioelectronics? The central obstacle to this vision is the absence of versatile interfaces that are able to control and regulate the means of communication between biological and electronic systems. This book summarizes the overall progress made to date in building such interfaces at the level of individual biomolecules and focuses on the latest efforts to generate device platforms that integrate biointerfaces with electronics. Chapter 1 introduces the general concept of dynamic interfaces for bioelectronics and gives an overview of the importance of materials and systems for switchable bioelectronics, introducing the reader to different biointerfaces. Chapter 2 pieces together different types of stimuli-responsive polymers and applications. Chapter 3 lays special emphasis on stimuli-responsive polymers with tunable release kinetics and describes the importance of polymer design for delivery applications. Chapter 4 reviews the field of conformational switching in nanofibers for gas-sensing applications. Finally, Chapter 5 focuses on molecular imprinting polymers as recognition elements for sensing applications. As informative as it is lucid, this handbook makes an essential resource for advanced undergraduate- and graduate-level students in chemistry, as well as researchers in polymer science and electrochemistry, especially those with an interest in responsive polymers and biosensors.

Smart Polymeric Nano-Constructs in Drug Delivery
Smart Polymeric Nano-Constructs in Drug Delivery

Author: Suresh P Vyas

Publisher: Academic Press

Published: 2022-11-12

Total Pages: 626

ISBN-13: 0323913997

DOWNLOAD EBOOK

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. - Provides comprehensive overview of the potential role of polymeric systems in drug delivery - Explores the design, synthesis, and application of different smart material-based delivery systems - Includes fundamental and clinical applications

Advanced Molecularly Imprinting Materials
Advanced Molecularly Imprinting Materials

Author: Ashutosh Tiwari

Publisher: John Wiley & Sons

Published: 2016-11-09

Total Pages: 724

ISBN-13: 1119336317

DOWNLOAD EBOOK

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Functional Hydrogels in Drug Delivery
Functional Hydrogels in Drug Delivery

Author: Umile Gianfranco Spizzirri

Publisher: CRC Press

Published: 2017-08-10

Total Pages: 362

ISBN-13: 149874902X

DOWNLOAD EBOOK

The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.

Handbook of Molecularly Imprinted Polymers
Handbook of Molecularly Imprinted Polymers

Author: Carmen Alvarez-Lorenzo

Publisher: Smithers Rapra Technology

Published: 2013-12

Total Pages: 400

ISBN-13: 9781847359599

DOWNLOAD EBOOK

Molecular imprinting technology has become a relevant tool for the synthesis of polymeric materials with the unique feature of being able to recognise specific target molecules and to bind them preferably among many others. Such an outstanding property makes molecularly imprinted polymer(s) (MIP) well suited for a wide range of applications in fields as diverse as analytical techniques, bioremediation, catalysis or drug delivery. Information regarding MIP has exponentially increased in recent years, being collected in a large variety of scientific journals, monographs and proceedings.This Handbook provides an overview of the state of the art of MIP by organising the information in an educational and practical way, with useful guidelines for newcomers to the field regarding monomer selection, polymerisation conditions and MIP conditioning for each given purpose.