Molecular Recognition of Proteins and DNA
Author: Ho Leung Ng
Publisher:
Published: 2001
Total Pages: 182
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author: Ho Leung Ng
Publisher:
Published: 2001
Total Pages: 182
ISBN-13:
DOWNLOAD EBOOKAuthor: JASON A. MCEVOY
Publisher: Lulu.com
Published: 2011
Total Pages: 322
ISBN-13: 0359602312
DOWNLOAD EBOOKAuthor: F. Diederich
Publisher: Springer Science & Business Media
Published: 2013-04-17
Total Pages: 274
ISBN-13: 366203574X
DOWNLOAD EBOOKReasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago. Today, it is clearly recognized that molecular recognition impacts and determines all life processes. It has become a key research field in both chemistry and biology and the emerging interface of what now is being called "chemical biology". The technological advances derived from this knowledge are particularly important, diverse, and directly evident in the pharmaceutical industry. Under the auspices of the Ernst Schering Research Foundation, a workshop held in Berlin in February 1998 addressed novel basic developments of potential relevance to drug research efforts. A balance of timely research topics in molecular recognition is presented in the lectures delivered by a multidisciplinary international panel of renowned scholars and documented in this volume.
Author: Julia Maree Sheldon
Publisher:
Published: 1999
Total Pages: 482
ISBN-13:
DOWNLOAD EBOOKAuthor: Shawn Yvette Stevens
Publisher:
Published: 1997
Total Pages: 400
ISBN-13:
DOWNLOAD EBOOKAuthor: Bruce Alberts
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
DOWNLOAD EBOOKAuthor: Abhijit Saha
Publisher: Springer
Published: 2018-03-22
Total Pages: 126
ISBN-13: 9811087466
DOWNLOAD EBOOKIn this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to detect the most important biological phenomena using the photochemistry of BrU-labeled DNA. The study began with the design and development of small molecules that can induce pluripotency genes. To deal with the important issue of cell permeability of the original compound, a new analogue of the original with improved gene expression was designed and synthesized. Using the photochemistry of BrU-labeled DNA, crucial biological phenomena such as cooperativity between transcription factors were detected. For the first time, the cooperativity was examined by excess electron transfer assay. DNA was also studied very carefully in order to understand the mechanism of the double-strand break in the UVA micro-irradiation technique. The mechanism of the double strand remained untouched. Nevertheless, the double-strand break mechanism was clearly demonstrated by Hoechst dye, as shown in this book.
Author: Zeno Simon
Publisher: CRC Press
Published: 1993-06-16
Total Pages: 356
ISBN-13: 9780849353987
DOWNLOAD EBOOKSpecific Interaction and Biological Recognition Processes is devoted to two major aspects of biological processes: specificity in biological recognition and the recognition processes themselves. Topics covered in specificity include the theoretical basis for specificity in biological recognition; the thermodynamic and chemical equilibrium background; and consideration of the relationship between size of combining sites and specificity. The use of semi-emperical potentials for calculating interaction energies and the potential of quantum chemistry methods for calculating receptor-effector affinities are also discussed. The various recognition processes described include DNA replication, transcription, translation, enzymatic reactions, transmembrane transport processes, mechanisms of action of hormones and other chemical messengers, and self-nonself recognition in immunology. Specific Interaction and Biological Recognition Processes will be a useful reference for molecular biologists, biochemists, enzymologists, immunologists oncologists, pharmaceutical researchers, and others interested in the topic.
Author: Richard Wolowacz
Publisher:
Published: 1993
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: 京極好正
Publisher:
Published: 1992
Total Pages: 304
ISBN-13:
DOWNLOAD EBOOK