Molecular Mechanisms for Sensory Signals

Molecular Mechanisms for Sensory Signals

Author: Edward M. Kosower

Publisher: Princeton University Press

Published: 2017-03-14

Total Pages: 457

ISBN-13: 1400887089

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Pursuing the questions of how we learn and how memory is made, Edward Kosower introduces a novel and rich approach to connecting molecular properties with the biological properties that enable us to write and read, to create culture and ethics, and to think. Here he examines what happens within a single cell in reaction to external stimuli, and shows the parallels between single cell and multicellular responses. To address the problem of "learning," Kosower explains the molecular mechanisms of responses to input from taste, olfactory, and visual receptors. He then shows how these and other processes serve as the basis for memory. This study covers such signals for the molecular process of learning as pheromones (the molecular signals mediating behavior), light (activates the G-protein receptor, rhodopsin), and acetylcholine (opens the nicotinic acetylcholine receptor). Kosower's discussion of the structure and function of these complex molecules has direct implications for such areas as molecular neurobiology, bioorganic chemistry, and drug design, in elucidating approaches to the structure of drug targets. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.


Neuromorphic Olfaction

Neuromorphic Olfaction

Author: Krishna C. Persaud

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 237

ISBN-13: 1439871728

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Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p


The Neurobiology of Olfaction

The Neurobiology of Olfaction

Author: Anna Menini

Publisher: CRC Press

Published: 2009-11-24

Total Pages: 438

ISBN-13: 1420071998

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Comprehensive Overview of Advances in OlfactionThe common belief is that human smell perception is much reduced compared with other mammals, so that whatever abilities are uncovered and investigated in animal research would have little significance for humans. However, new evidence from a variety of sources indicates this traditional view is likely


Neural Plasticity and Memory

Neural Plasticity and Memory

Author: Federico Bermudez-Rattoni

Publisher: CRC Press

Published: 2007-04-17

Total Pages: 368

ISBN-13: 1420008412

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A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq


TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

Author: Wolfgang B. Liedtke, MD, PH.D.

Publisher: CRC Press

Published: 2006-09-29

Total Pages: 502

ISBN-13: 1420005847

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Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st


Cellular Signal Processing

Cellular Signal Processing

Author: Friedrich Marks

Publisher: Garland Science

Published: 2017-05-17

Total Pages: 982

ISBN-13: 1351677217

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Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.


Human Herpesviruses

Human Herpesviruses

Author: Ann Arvin

Publisher: Cambridge University Press

Published: 2007-08-16

Total Pages: 1325

ISBN-13: 1139461648

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This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.


Two-component Signal Transduction

Two-component Signal Transduction

Author: James A. Hoch

Publisher: Amer Society for Microbiology

Published: 1995

Total Pages: 488

ISBN-13: 9781555810894

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The human enteroviruses, particularly the polio viruses, have had a significant role in the history of medicine and microbiology; and continue to cause clinical problems, as well as provide targets for molecular investigation. This book offers a link between the basic science and clinical medicine.


Quantitative EEG, Event-Related Potentials and Neurotherapy

Quantitative EEG, Event-Related Potentials and Neurotherapy

Author: Juri D. Kropotov

Publisher: Academic Press

Published: 2010-07-28

Total Pages: 601

ISBN-13: 008092297X

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While the brain is ruled to a large extent by chemical neurotransmitters, it is also a bioelectric organ. The collective study of Quantitative ElectroEncephaloGraphs (QEEG-the conversion of brainwaves to digital form to allow for comparison between neurologically normative and dysfunctional individuals), Event Related Potentials (ERPs - electrophysiological response to stimulus) and Neurotherapy (the process of actually retraining brain processes to) offers a window into brain physiology and function via computer and statistical analyses of traditional EEG patterns, suggesting innovative approaches to the improvement of attention, anxiety, mood and behavior.The volume provides detailed description of the various EEG rhythms and ERPs, the conventional analytic methods such as spectral analysis, and the emerging method utilizing QEEG and ERPs. This research is then related back to practice and all existing approaches in the field of Neurotherapy - conventional EEG-based neurofeedback, brain-computer interface, transcranial Direct Current Stimulation, and Transcranial Magnetic Stimulation - are covered in full. While it does not offer the breadth provided by an edited work, this volume does provide a level of depth and detail that a single author can deliver, as well as giving readers insight into the personl theories of one of the preeminent leaders in the field. - Provide a holistic picture of quantitative EEG and event related potentials as a unified scientific field - Present a unified description of the methods of quantitative EEG and event related potentials - Give a scientifically based overview of existing approaches in the field of neurotherapy - Provide practical information for the better understanding and treatment of disorders, such as ADHD, Schizophrenia, Addiction, OCD, Depression, and Alzheimer's Disease


The Sensory Hand

The Sensory Hand

Author: Vernon B. Mountcastle

Publisher: Harvard University Press

Published: 2005-12-30

Total Pages: 648

ISBN-13: 9780674019744

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Vernon Mountcastle has devoted his career to studying the neurophysiology of sensation in the hand. In The Sensory Hand he provides an astonishingly comprehensive account of the neural underpinnings of the rich and complex tactile experiences evoked by stimulation of the hand.