Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates
Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates

Author: Antoine Blancher

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 578

ISBN-13: 3642590861

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Zoologists have categorized primates into a single order, and no one doubts today that they share a common ancestry. Humans and Old and New World non human primate species, from the lemurs of Madagascar to the African anthro poid apes, represent diverging branches of an evolutionary common trunk. Along with species-specific characters, all primates have retained a number of ancestral traits, relics of their common origin. The comparative study of these species-specific and ancestral traits makes it possible to reconstruct the evolu tionary pathways of humans and nonhuman primates. The discovery of the human blood groups and, later, of the Major Histocom patibility Complex (MHC) had a seminal effect on the field of human genetics, providing the first sound examples of mendel ian polymorphisms. The use of blood group and MHC alleles as genetic markers in biological anthropology gen erated a conceptual revolution and persuaded researchers to begin to think in terms of populations and not only intems of typology. The counterparts of these human red and white cell antigens were found and studied in nunhuman primates, and progress in this field is summarized in this book.

Human Blood Groups
Human Blood Groups

Author: Geoff Daniels

Publisher: John Wiley & Sons

Published: 2013-01-16

Total Pages: 950

ISBN-13: 1118493540

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Human Blood Groups is a comprehensive and fully referenced text covering both the scientific and clinical aspects of red cell surface antigens, including: serology, inheritance, biochemistry, molecular genetics, biological functions and clinical significance in transfusion medicine. Since the last edition, seven new blood group systems and over 60 new blood group antigens have been identified. All of the genes representing those systems have now been cloned and sequenced. This essential new information has made the launch of a third edition of Human Blood Groups, now in four colour, particularly timely. This book continues to be an essential reference source for all those who require clinical information on blood groups and antibodies in transfusion medicine and blood banking.

Basics in Human Evolution
Basics in Human Evolution

Author: Michael P Muehlenbein

Publisher: Academic Press

Published: 2015-07-24

Total Pages: 609

ISBN-13: 0128026936

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Basics in Human Evolution offers a broad view of evolutionary biology and medicine. The book is written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field. From evolutionary theory, to cultural evolution, this book fills gaps in the readers' knowledge from various backgrounds and introduces them to thought leaders in human evolution research. - Offers comprehensive coverage of the wide ranging field of human evolution - Written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field - Provides expertise from leading minds in the field - Allows the reader the ability to gain exposure to various topics in one publication

Blood Banking and Transfusion Medicine
Blood Banking and Transfusion Medicine

Author: Christopher D. Hillyer

Publisher: Elsevier Health Sciences

Published: 2006-10-18

Total Pages: 910

ISBN-13: 0443069816

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Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Protecting Infants through Human Milk
Protecting Infants through Human Milk

Author: Larry K. Pickering

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 506

ISBN-13: 1475742428

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Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.

Human Gene Evolution
Human Gene Evolution

Author: David Neil Cooper

Publisher: Elsevier

Published: 1999-11-03

Total Pages: 520

ISBN-13: 9780121878702

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Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field. Structure and function in the human genome The evolution of gene structure Mutational mechanisms in evolution

Major Histocompatibility Complex
Major Histocompatibility Complex

Author: M. Kasahara

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 574

ISBN-13: 4431658688

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Every biological system is the outcome of evolution and has a history all its own. This history dictates how the system works and why it has certain properties and not others. This is why we need to study not only the structure and function, but also the history of the system. This argument undoubtedly applies to the study of the immune system and also to the study of the major histocompatibility complex (MHC). Since 1989, researchers of various scientific disciplines who share a deep inter est in MHC evolution have held a meeting every two years to discuss their latest research developments, exchange ideas, and foster friendship. Together with my colleagues Drs. Naoyuki Takahata and Yoko Satta, I organized the Sixth Interna tional Workshop on MHC Evolution in Hayama, Japan, May 25-29, 1999. This volume is the proceedings of that conference. It covers diverse topics pertinent to MHC evolution, including the origin of the adaptive immune system, the organi zation of the MHC in humans and other model vertebrates, MHC-parasite co evolution, and the nature and origin of MHC polymorphism. I hope that this book will be of interest not only for MHC researchers and immunologists, but also for other specialists who are interested in the evolution of biological systems in gen eral.

Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations
Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations

Author: May-jean King

Publisher: World Scientific

Published: 2000-07-04

Total Pages: 419

ISBN-13: 1911298933

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This important book uses selected molecules expressed on erythrocytes, lymphocytes, platelets and granulocytes to illustrate how genetic polymorphisms and variations in these molecules can affect their structure and function in mature human blood cells. The examples described tend to have a clinical association. Human blood group antigens and HLA antigens are classic examples of genetic polymorphism and they are important in blood transfusion and organ transplantation, respectively. In common with the blood group antigens, the polymorphic and variant antigens on platelets and granulocytes can be targets for antibodies in feto-maternal antigen incompatibility and transfusion reactions. Certain inherited haemolytic anaemias can be attributed to some of the polymorphic and variant forms of erythrocyte anion transport protein, spectrin, and glucose-6-phosphate dehydrogenase which exhibit abnormal structural or functional properties. Similarly, the study of cytokine gene polymorphism can provide a further understanding of the immune/inflammatory diseases and allogeneic transplantation./a

Blood and Bone Marrow Pathology E-Book
Blood and Bone Marrow Pathology E-Book

Author: Anna Porwit

Publisher: Elsevier Health Sciences

Published: 2011-05-27

Total Pages: 724

ISBN-13: 0702045357

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Chapters have been totally rewritten and some new chapters have been added especially on myeloid malignancies, in line with the WHO 2008 Classification All chapters have been revised to include new aspects of molecular biology and updated concerning flow cytometry diagnostics Greater emphasis on practical diagnostic aspects for all disorders Brand new editorial and contributing author team. Full Online text through Expert Consult. Full downloadable Image Bank

Human Gene Evolution
Human Gene Evolution

Author: David Cooper

Publisher: Taylor & Francis

Published: 2024-11-15

Total Pages: 665

ISBN-13: 1040287999

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The story of our evolutionary past is told in our genome sequence. Human Gene Evolution deals with the origins of human genes, describes their structure, function, organisation and expression. The text integrates our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms underlying evolutionary change.