Building on the strengths of previous editions, the Sixth Edition of Modern Pharmacology with Clinical Applications continues to provide an up-to-date and comprehensive textbook for students of pharmacology. Focusing on the clinical application of drugs within a context of the major principles of pharmacology, this text supplies both students and faculty with an introduction to modern pharmacotherapeutics.
**Selected for Doody's Core Titles® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. - Presents the essential knowledge for effective practice of clinical pharmacology - Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology - Offers an extensive regulatory section that addresses US and international issues and guidelines - Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
This is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs but in this context also the social impact which drugs have in modern societies is highlighted. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book * Covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases * Gives guidance on how doctors should act so that drugs can be used effectively and safely * Encourages the rational use of drugs in society This book brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.
This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. - Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy - Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course - Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study - Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry - Expanded coverage of pharmacogenetics - Expanded coverage of drug transporters and their role in interactions - Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions - A new chapter on drug discovery that focuses on oncologic agents - Inclusion of therapeutic antibodies in chapter on biotechnology products
The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine—enhanced by a new full-color illustrations Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, Fourteenth Edition covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors’ many years’ experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students. To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations (many new to this edition), Basic & Clinical Pharmacology features numerous summary tables and diagrams that encapsulate important information. • Student-acclaimed summary tables conclude each chapter • Everything students need to know about the science of pharmacology and its application to clinical practice • Strong emphasis on drug groups and prototypes • NEW! 100 new drug tables • Includes 330 full-color illustrations, case studies, and chapter-ending summary tables • Organized to reflect the syllabi of pharmacology courses • Descriptions of important new drugs
Global collaboration is the cornerstone of scientific advancement. Frontiers in Pharmacology has organized a series of special edition Research Topics, with the goal of highlighting the latest advancements in Ethnopharmacology across the globe, showcasing the academic excellence and high-quality work of internationally recognized researchers. These collections aim to shed light on the recent progress made across the entire breadth of the Ethnopharmacology field, and reflect on the future challenges faced by researchers across borders.
The fascinating world of “Advanced Pharmacology I" is the subject to explore. This book takes us on an exciting journey through the rapidly evolving science of pharmacology, where novel concepts and groundbreaking findings are transforming our understanding of and reliance on medicine. The subject is designed to strengthen the basic knowledge in the field of pharmacology and to impart recent advances in the drugs used for the treatment of various diseases. In addition, this subject helps the students to understand the concepts of Pharmacological and mechanisms involved. This book's rigorous planning ensures a thorough comprehension of the subject matter by covering a broad variety of subjects that line up with the drug actions. We go into the fundamentals of controlled medication delivery systems in Unit I. We discuss general pharmacology, in which we discuss drug development, drug distribution, drug safety, and effectiveness. Further, the new drug development and its stages have been considered. In the next chapter of Unit 1, the concepts of pharmacokinetics and pharmacodynamics are presented. In pharmacokinetics, we investigate the drug's absorption, distribution, biotransformation, and elimination. Concepts of linear and non-linear compartment models and in pharmacodynamics, the mechanism of drug action, receptors, structural and functional families of receptors, and quantitation of drug-receptor interaction have been briefly discussed briefly. Neurotransmission is introduced in Unit II. We explore the general concept of neurotransmission in this unit. Neurohumoral transmission in the autonomic and central nervous systems has been discussed here. Further, we discussed the concept of NANC. In Unit III, we address systemic pharmacology, in which we go through the pathophysiology of diseases, mechanisms of action, pharmacology, and toxicology of existing as well as novel drugs. It has been looked into how parasympathomimetics and sympathomimetics affect the neuromuscular junction and how they affect the autonomic nervous system.
