The present volume "Manganese" D 6 continues the description of the manganese com plexes. The introduction on p. 1 shows the classes of complexes that have already been described in Chapters 1 through 29 in Volumes D1 to D 5. Complexes with Schiff bases and related compounds (e.g., hydrazones, semicarbazones, or thiosemicarbazones) are now described in Chapters 30 and 31 of this volume and complexes with carbazones, thiocarba zones and formazans in Chapter 32. Complexes with Schiff bases play a central role in the development of coordination chemistry. The publications range from synthetic aspects to modern physicochemically or biochemically relevant investigations on these compounds. The huge number of studies results from the fact that these ligands may contain various donor atoms, in addition to the azomethine group, and thus can occur with variable denticities. About 1700 compounds derived from 808 different ligands are described in the present volume. Their arrangement is by ligand type and number of azomethine groups.
Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.
Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders. The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that associates manganese exposure to potential human diseases. Any scientists, health professional or regulator involved with metal exposure and toxicology should find this volume essential reading. Students and researchers in neurotoxicology will also find this book a useful reference.
Abstract: Research results concerning aspects of iron (Fe) bioavailability from various foods and interactions of Fe with other nutrients are reported by experts for nutritionists and food and agricultural chemists. Several areas address the determination of available Fe in foods, changes in Fe availability caused by food processing, physiochemical food properties affecting Fe chemstry, and food additives that either enhance or inhibit Fe intake. Therelationship of ascorbic acid in aiding Fe absorption is discussed, as is the inhibitory action of dietary fiber. Twoimportant human nutrition aspects cover Fe availability in human milk, and the differences in Fe utilization between vegetarians and omnivores. When careful choice is made of food combinations, food additives, and proper processing methods, humans can utilize a greater portion of the Fe in low-energy foods. (wz).
Sixty years ago at the Waite Agricultural Research Institute, G. Samuel, a plant pathologist, and C. S. Piper, a chemist, published their conclusion that the cause of roadside take-all, a disease of oats, was manganese deficiency. This report, together with the concurrent and independent studies of W. M. Carne in Western Australia were the first records of manganese deficiency in Australia and came only six years after McHargue's paper which is generally accepted as the final proof of the essentiality of this element. There must have been a few doubts for some people at the time, however, as the CAB publication, 'The Minor Elements of the Soil' (1940) expressed the view that further evidence to this effect was provided by Samuel and Piper. Their historic contributions are recognised by the International Symposium on Manganese in Soils and Plants as it meets on the site of their early labours to celebrate the 60th anniversary. This year Australians also acknowledge 200 years of European settlement in this country and so the Symposium is both a Bicentennial and a diamond jubilee event which recognises the impact of trace elements on agricultural development in Australia. In a broader sense, a symposium such as this celebrates, as it reviews, the efforts of all who over the ages have contributed to our knowledge of manganese in soils and plants.
Progress in our knowledge of thermodynamics and physico-chemical factors in manganese ferroalloy production has developed rapidly during the past twenty-five years or so. The authors' intention has been to use this basic knowledge in discussions of industrial manganese ferroalloy production. The book presents the principles and current knowledge of processes in the production of high carbon ferromanganese, silicomanganese and low carbon manganese alloys. The book is intended for professionals working in production, plant design or development. It will also be useful for researchers in industry, universities and research institutes. The book can be used as a textbook for courses in extractive and process metallurgy, and for company in-house courses. Thermodynamics of the slag and metal systems are extensively covered. Computational modelling based on assessed thermochemical databases has made it possible to calculate and present a large number of phase and equilibrium diagrams. These diagrams are useful for easy understanding and analysis of the complex heterogeneous equilibria in the manganese ferroalloy metallurgy. The manganese ferroalloys are mainly produced in electric submerged arc furnaces. Electrical relations are briefly discussed. Supply of raw materials, especially manganese ores and coke, is extremely important for the manganese industry. The book gives the reader appropriate knowledge regarding the selection the best of available raw materials. Environmental issues, including greenhouse gas emissions and climate changes, are of growing concern to ferroalloy producers. Carbon will always be needed as a reducing agent, and consequently emission of CO2 gas is inevitable. The book describes solutions to dealing with pollution problems and gives the latest guidelines for greenhouse gas inventories.
As the importance and dependence of specific mineral commodities increase, so does concern about their supply. The United States is currently 100 percent reliant on foreign sources for 20 mineral commodities and imports the majority of its supply of more than 50 mineral commodities. Mineral commodities that have important uses and face potential supply disruption are critical to American economic and national security. However, a mineral commodity's importance and the nature of its supply chain can change with time; a mineral commodity that may not have been considered critical 25 years ago may be critical today, and one considered critical today may not be so in the future. The U.S. Geological Survey has produced this volume to describe a select group of mineral commodities currently critical to our economy and security. For each mineral commodity covered, the authors provide a comprehensive look at (1) the commodity's use; (2) the geology and global distribution of the mineral deposit types that account for the present and possible future supply of the commodity; (3) the current status of production, reserves, and resources in the United States and globally; and (4) environmental considerations related to the commodity's production from different types of mineral deposits. The volume describes U.S. critical mineral resources in a global context, for no country can be self-sufficient for all its mineral commodity needs, and the United States will always rely on global mineral commodity supply chains. This volume provides the scientific understanding of critical mineral resources required for informed decisionmaking by those responsible for ensuring that the United States has a secure and sustainable supply of mineral commodities.
A readable, informative, fascinating entry on each one of the 100-odd chemical elements, arranged alphabetically from actinium to zirconium. Each entry comprises an explanation of where the element's name comes from, followed by Body element (the role it plays in living things), Element ofhistory (how and when it was discovered), Economic element (what it is used for), Environmental element (where it occurs, how much), Chemical element (facts, figures and narrative), and Element of surprise (an amazing, little-known fact about it). A wonderful 'dipping into' source for the familyreference shelf and for students.
