For the second edition of 'Microreactors in Organic Chemistry and Catalysis' all chapters have been revised and updated to reflect the latest developments in this rapidly developing field. This new edition has 60% more content, and it remains a comprehensive publication covering most aspects of the topic. The use of microreactors in homogeneous, heterogeneous as well as biphasic reactions is covered in the main part of the book, together with catalytic, bioorganic and automation approaches. The initial chapters also provide a solid physical chemistry background on fluidics in microdevices. Finally, a chapter on industrial applications and developments covers recent progress in process chemistry. An excellent reference for beginners and experts alike.
This one-stop reference is the first book on this emerging and rapid developing field with a focus on synthesis and catalysis. As such, it covers all aspects from academia and industry in a clearly structured way. Leading experts provide the background information as an initial aid for newcomers to the field, while chapters on different reaction types and industrial applications make this an equally vital resource for specialists. From the contents: - Introduction and background - Fabrication of microractors - Properties and use of microreactors - Organic chemistry in microreactors - Homogeneous reactions (including photochemical and electrochemical reactions) - Heterogeneous reactions - Biphasic reactions (liquid/liquid, liquid/gas) - Bioorganic reactions - Industrial applications Thomas Wirth is Professor of Organic Chemistry at Cardiff University in Wales. After a postdoctoral stay with Kaoru Fuji at Kyoto University as a JSPS fellow, he started his independent research in the group of Bernd Giese in Basel, Switzerland. He was invited as a visiting professor to various places: University of Toronto, Canada (1999), Chuo University in Tokyo, Japan (2000), Osaka University, Japan (2004). He was awarded the Werner-Prize from the New Swiss Chemical Society in 2000. He is the author of about 80 publications and has written or edited 4 books.
This is the first book in the field to focus on these aspects, providing extremely valuable information unavailable elsewhere for anyone seeking the practical application of microreactor technology in preparative chemistry. The topics covered branch out in three different directions. To begin with, the knowledge necessary for the preparative chemistry concerning the influence of the so-called microeffects on the reaction procedure and on mass and heat transfer as well as the surface phenomena are provided in detail. Next, practical aspects of the synthesis of various basic chemicals and fine chemicals, polymers, bioproducts and nanoparticles are discussed, including important advice for both the researcher and industrial chemist. Finally, reaction examples in microreactors whose reaction guidance are best understood are given together with universally applicable correlations as well as modeling approaches and transfer potential on related reaction systems. With its specific instructions, tips and experimental procedures for product syntheses as well as the inclusion of both the technical and theoretical background this is a must-have for beginners and experts alike working in this emerging field.
While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists c
This one-stop reference is the first book on this emerging and rapid developing field with a focus on synthesis and catalysis. As such, it covers all aspects from academia and industry in a clearly structured way. Leading experts provide the background information as an initial aid for newcomers to the field, while chapters on different reaction types and industrial applications make this an equally vital resource for specialists.
Microreaction technology, with its unprecedented heat and mass transfer advantages as well as uniform residence time and flow pattern, is one of the few technologies with potential to develop efficient, environmentally benign, and compact processes. Novel fabrication and processing techniques, equipment, and operational methods are resulting in spectacular developments that go beyond "traditional" chemical engineering. These new developments promise improvements in process plants, and lead to the transformation of our concept of chemical plants into compact, safe, energy-efficient, and environmentally sustainable processes. Microsystems are now available in many devices for commercial applications including: micromixers and microreactors as alternative to batch production in pharmaceutical and fine chemical industry, lab-on-chip devices, microsensors, advanced rapid throughput chemical and catalyst screening tools (e.g. combi), distributed or portable power and chemical production, distributed heating and cooling, and even out of this world applications with NASA. A wide diversity of subjects are discussed in this book ranging from catalysis to fuel processing to combinatorial techniques to separations to novel reactors all of which are enabled by microtechnology principles. World renowned pioneers (Klavs Jensen, Volker Hessel, Jennifer Holmgren, and Galip Akay) provide accounts on both historical developments and the current state of the art as well as insights into future research and development in microreactor and process intensification. Research and developments are presented by industry, universities, U.S. National Laboratories, and other laboratories located in the United States and throughout the world. It is composed of peer-reviewed chapters from both contributing and invited authors. The review and original research topics include (1) introductory and general overviews, (2) microreactors- including catalysts for microreactors, fuel processors, milli-second contact time catalysis, gas to liquid technology, and biomass conversion; and (3) process intensification such as micro mixers, reactive membranes, and intensification of separation operations.
A comprehensive overview covering the principles and preparation of catalysts, as well as reactor technology and applications in the field of organic synthesis, energy production, and environmental catalysis. Edited and authored by renowned and experienced scientists, this reference focuses on successful reaction procedures for applications in industry. Topics include catalyst preparation, the treatment of waste water and air, biomass and waste valorisation, hydrogen production, oil refining as well as organic synthesis in the presence of heterogeneous and homogeneous catalysts and continuous-flow reactions. With its practical relevance and successful methodologies, this is a valuable guide for chemists at universities working in the field of catalysis, organic synthesis, pharmaceutical or green chemistry, as well as researchers and engineers in the chemical industry.
Presents general aspects of microreaction technology. Discusses in detail microfabrication techniques, micromixers, micro heat exchangers, microseparation systems, micosystems for liquid and gas phase reactions, gas/liquid microreactors, and microsystems for energy generation, catalyst, and material screening.
Have you ever wished you could speed up your organic syntheses without losing control of the reaction? Flash Chemistry is a new concept which offers an integrated scheme for fast, controlled organic synthesis. It brings together the generation of highly reactive species and their reactions in Microsystems to enable highly controlled organic syntheses on a preparative scale in timescales of a few seconds or less. Flash Chemistry: Fast Organic Synthesis in microsystems is the first book to describe this exciting new technique, with chapters covering: an introduction to flash chemistry reaction dynamics: how fast is the act of chemical transformation, what is the rate of reaction, and what determines the selectivity of a reaction? examples of why flash chemistry is needed: the rapid construction of chemical libraries, rapid synthesis of radioactive PET probes, and on-demand rapid synthesis in industry the generation of highly reactive species through thermal, microwave, chemical, photochemical, and electrochemical activation microsystems: What are microsystems and how are they made? Why is size so important? What are the characteristic features of microsystems? conduction and control of extremely fast reactions using microsystems applications of flash chemistry in organic synthesis polymer synthesis based on flash chemistry industrial applications of flash chemistry Flash Chemistry: Fast Organic Synthesis in Microsystems is an essential introduction to anyone working in organic synthesis, process chemistry, chemical engineering and physical organic chemistry concerned with fundamental aspects of chemical reactions an d synthesis and the production of organic compounds.
This book provides in a concise form the principles and applications of flow microreactors in organic and polymer synthesis. Recently, it became possible to conduct chemical reactions in a flow reactor in laboratory synthesis. The flow microreactor enables reactions that cannot be done in batch, opening a new possibility of chemical synthesis. Extremely fast mass and heat transfer and high-resolution residence time control are responsible for the remarkable features of that process. The book is not an exhaustive compilation of all known examples of flow microreactor synthesis. Rather, it is a sampling of sufficient variety to illustrate the concept, the scope, and the current state of flow microreactor synthesis. Researchers both in academia and in industry will be interested in this book because the topics encompassed by the book are vigorously studied in many university and company laboratories today.
