Principles and Methods of Toxicology, Fifth Edition
Principles and Methods of Toxicology, Fifth Edition

Author: A. Wallace Hayes

Publisher: CRC Press

Published: 2007-09-25

Total Pages: 2304

ISBN-13: 9780849337789

DOWNLOAD EBOOK

Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.

Introduction to Environmental Toxicology
Introduction to Environmental Toxicology

Author: Wayne Landis

Publisher: CRC Press

Published: 2010-12-16

Total Pages: 536

ISBN-13: 1439804109

DOWNLOAD EBOOK

After fifteen years and three editions, Introduction to Environmental Toxicology: Molecular Substructures to Ecological Landscapes has become a standard that defines the field of environmental toxicology, and the fourth edition is no exception. The authors take an integrated approach to environmental toxicology that emphasizes scale and context as important factors in understanding effects and management options. New in the Fourth Edition: New author, Dr. Ruth M. Sofield 8-page color insert New chapter on fate and transport of contaminants Emphasis on the use of all types of models in understanding how nature works Revised sections on synergy and atrazine toxicity Updated coverage of the analysis of impacts to populations, communities and ecosystems Enlarged risk assessment chapter with an in-depth description of a regional scale risk assessment This edition benefits from the insight of a new author, Dr. Ruth M. Sofield, who prepared the new chapter on the fate and transport of contaminants. The relationship between structure and toxicological properties has been a major theme of this book since its inception and this new chapter expands this fundamental concept to include fate and transport. In the early chapters the use of models in science is discussed and this theme carries throughout the rest of the book. So much has changed in the fifteen years since the publication of the first edition. The mid-1990s seem so long ago, when our understanding of environmental toxicology was very basic. Ecological risk assessment was in its very early stages and the consideration of the effects of toxicants on landscapes was only beginning. Computation was still hard, genes stayed put, and it was only becoming recognized that xenobiotics could have hormonal effects — developments that are taken for granted in this edition. Written by authors who teach this subject, a feature that is reflected in their straightforward style, the book provides a foundation for understanding environmental toxicology and its application.

Handbook of Ecotoxicology
Handbook of Ecotoxicology

Author: David J. Hoffman

Publisher: CRC Press

Published: 2002-11-13

Total Pages: 1316

ISBN-13: 142003250X

DOWNLOAD EBOOK

Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. Focusing on toxic substance and how they affect the ecosystems worldwide, the book presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. This is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

Sedimentology of Aqueous Systems
Sedimentology of Aqueous Systems

Author: Cristiano Poleto

Publisher: John Wiley & Sons

Published: 2010-02-05

Total Pages: 216

ISBN-13: 9781444317121

DOWNLOAD EBOOK

Sediments in aqueous systems are of increasing interest to academics, researchers, practitioners and stakeholders around the world. This book not only covers the characteristics of the sediments themselves, but also their physico-chemical impact on aquatic habitats and subsequent management implications. There is a strong focus on methods and instrumentation for collecting data and monitoring of environmental sediment quality and as a result, a wide range of environments are considered - from urban areas to freshwater estuaries and marine ecosystems. The chapters have been written by international specialists in the field, ensuring a good breadth of examples, experiences and case studies throughout. This book will appeal to a broad spectrum of interests from geographers, to engineers and environmental scientists, and at undergraduate to post graduate and academic researcher levels.