Occupational Neurology

Occupational Neurology

Author:

Publisher: Elsevier

Published: 2015-11-09

Total Pages: 546

ISBN-13: 044462628X

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Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders. This timely collection provides not only a complete scientific reference on the chemical origin of this class of neurological and psychiatric disorders, but also a practical guide to diagnosis and treatment challenges and best practices. Handbook of Clinical Neurology Series The first volume of the Handbook of Clinical Neurology under the editorship of George Bruyn and Pierre Vinken was published in 1968. In 1982, the series was brought to an interim conclusion with the publication of the cumulative index volume (Volume 44). By that stage, the Handbook had come to represent one of the largest scientific works ever published. It enjoys a high reputation in specialist media circles throughout the world. After the series was concluded in 1982, it was realized that an update of the material was imperative. Accordingly, a revised series was planned and published over the following years, concluding with the publication of another cumulative index to both series (Volume 76-78) in 2002. Since then, George Bruyn has passed away and Pierre Vinken has retired, but the need for a further new series, incorporating advances in the field, again become necessary. Professors Michael J. Aminoff, François Boller and Dick F. Swaab have with enthusiasm taken on the responsibility of supervising the preparation of a third series, the first volumes of which were published in 2003. Now, more than 130 volumes after the first published, the Handbook of Clinical Neurology series continues to have an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology. - Provides comprehensive coverage of neurotoxins, especially in the workplace - Details the latest science as the foundation for neurotoxicity diagnosis and treatment - Presents coverage of the diagnosis and treatment essential for clinical neurologists and occupational medicine specialists


Poisoning in the Modern World

Poisoning in the Modern World

Author: Ozgur Karcioglu

Publisher: BoD – Books on Demand

Published: 2019-06-19

Total Pages: 130

ISBN-13: 1838807853

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Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.


Neurotoxicity of Metals

Neurotoxicity of Metals

Author: Michael Aschner

Publisher: Springer

Published: 2017-09-09

Total Pages: 377

ISBN-13: 331960189X

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Assembles international authorities to address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.


Molecular, Clinical and Environmental Toxicology

Molecular, Clinical and Environmental Toxicology

Author: Andreas Luch

Publisher: Springer Science & Business Media

Published: 2012-06-07

Total Pages: 580

ISBN-13: 3764383402

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Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.


Metal Chelation in Medicine

Metal Chelation in Medicine

Author: Robert R Crichton

Publisher: Royal Society of Chemistry

Published: 2016-10-18

Total Pages: 336

ISBN-13: 1782623892

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Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.


Neurotoxicity of Aluminum

Neurotoxicity of Aluminum

Author: Qiao Niu

Publisher: Springer

Published: 2018-10-12

Total Pages: 191

ISBN-13: 9811313709

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This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.


Metal, Metal Oxides and Metal Sulphides for Biomedical Applications

Metal, Metal Oxides and Metal Sulphides for Biomedical Applications

Author: Saravanan Rajendran

Publisher: Springer Nature

Published: 2021-01-25

Total Pages: 360

ISBN-13: 3030564134

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This book presents recent advances in inorganic nanomaterials for healthcare, with focus on the synthesis, medical applications and toxicity of metals, metal oxides and metal sulfides. Major applications include diagnosis, bioimaging, biosensing, healing and therapy in cancer, diabetes, cardiovascular diseases, obesity, metabolic syndrome, dentistry and antimicrobials.


Essentials of Toxicology for Health Protection

Essentials of Toxicology for Health Protection

Author: David Baker

Publisher: Oxford University Press

Published: 2012-03-15

Total Pages: 368

ISBN-13: 9780199652549

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Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.


Methylmercury and Neurotoxicity

Methylmercury and Neurotoxicity

Author: Sandra Ceccatelli

Publisher: Springer Science & Business Media

Published: 2012-03-23

Total Pages: 375

ISBN-13: 146142383X

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Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHg’s accumulation in fish. Latest US statistics indicate that 46 States have fish consumption advisories. In addition, Hg is a common pollutant in hazardous waste sites, with an estimated 3-4 million children living within one mile of at least one of the 1,300+ active hazardous waste sites in the US. The effects on intellectual function in children prenatally exposed to MeHg via maternal fish consumption have been the subject of two on-going major, prospective, longitudinal studies in the Seychelles and the Faroe Islands. It is important to recognize that the risk for MeHg exposure is not limited only to islanders with high fish consumption. This book will provide state-of-the-art information to the graduate student training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the reader up to date on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies.