This volume presents state-of-the art design, analysis and integration approaches for biomedical data including novel statistical models for a comprehensive and powerful synthesis and assessment of scientific evidence. Chapters detail principles of systematic reviews, semi-automated tools for systematic searches, fixed- and random-effects meta-analytical models, living systematic reviews, meta-analysis of genetic studies, meta-analysis of pragmatic and explanatory trials, network meta-analysis, and other modern approaches for data synthesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, the Meta- Research: Methods and Protocols book, written by global experts, will introduce the reader in a step-by-step process to the methods of the vital and highly promising field of evidence synthesis.
This title provides step-by-step directions for how to conduct a meta-study, as well as recommendations for tools and standards for the application of this approach.
Offering pragmatic guidance for planning and conducting a meta-analytic review, this book is written in an engaging, nontechnical style that makes it ideal for graduate course use or self-study. The author shows how to identify questions that can be answered using meta-analysis, retrieve both published and unpublished studies, create a coding manual, use traditional and unique effect size indices, and write a meta-analytic review. An ongoing example illustrates meta-analytic techniques. In addition to the fundamentals, the book discusses more advanced topics, such as artifact correction, random- and mixed-effects models, structural equation representations, and multivariate procedures. User-friendly features include annotated equations; discussions of alternative approaches; and "Practical Matters" sections that give advice on topics not often discussed in other books, such as linking meta-analytic results with theory and the utility of meta-analysis software programs. ÿ
Major text including chapters on the following: defining outcome measures; assessing heterogeneity; using fixed effects methods and random effects models for combining study estimates; publication bias.
Covering the most important developments in meta-analysis from 1990 to 2004, this text presents new patterns in research findings as well as updated information on existing topics.
Meta-Analysis shows concisely, yet comprehensively, how to apply statistical methods to achieve a literature review of a common research domain. It demonstrates the use of combined tests and measures of effect size to synthesize quantitatively the results of independent studies for both group differences and correlations. Strengths and weaknesses of alternative approaches, as well as of meta-analysis in general, are presented.
Considers meta-analytic procedures (the quantitative summary of a research domain) in sufficient detail for readers either to carry them out for themselves, or evaluate the procedures when used by others and offers advice about the applicability of these techniques to specific research questions.
Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book
We live in a noisy world! In all applications (telecommunications, hands-free communications, recording, human-machine interfaces, etc.) that require at least one microphone, the signal of interest is usually contaminated by noise and reverberation. As a result, the microphone signal has to be "cleaned" with digital signal processing tools before it is played out, transmitted, or stored. This book is about speech enhancement. Different well-known and state-of-the-art methods for noise reduction, with one or multiple microphones, are discussed. By speech enhancement, we mean not only noise reduction but also dereverberation and separation of independent signals. These topics are also covered in this book. However, the general emphasis is on noise reduction because of the large number of applications that can benefit from this technology. The goal of this book is to provide a strong reference for researchers, engineers, and graduate students who are interested in the problem of signal and speech enhancement. To do so, we invited well-known experts to contribute chapters covering the state of the art in this focused field. TOC:Introduction.- Study of the Wiener Filter for Noise Reduction.- Statistical Methods for the Enhancement of Noisy Speech.- Single- und Multi-Microphone Spectral Amplitude Estimation Using a Super-Gaussian Speech Model.- From Volatility Modeling of Financial Time-Series to Stochastic Modeling and Enhancement of Speech Signals.- Single-Microphone Noise Suppression for 3G Handsets Based on Weighted Noise Estimation.- Signal Subspace Techniques for Speech Enhancement.- Speech Enhancement: Application of the Kalman Filter in the Estimate-Maximize (EM) Framework.- Speech Distortion Weighted Multichannel Wiener Filtering Techniques for Noise Reduction.- Adpative Microphone Arrays Employing Spatial Quadratic Soft Constraints and Spectral Shaping.- Single-Microphone Blind Dereverberation.- Separation and Dereverberation of Speech Signals with Multiple Microphones.- Frequency-Domain Blind Source Separation.- Subband Based Blind Source Separation.- Real-Time Blind Source Separation for Moving Speech Signals.- Separation of Speech by Computational Auditory Scene Analysis
The Fifth Edition of Harris Cooper′s bestselling text offers practical advice on how to conduct a synthesis of research in the social, behavioral, and health sciences. The book is written in plain language with four running examples drawn from psychology, education, and health science. With ample coverage of literature searching and the technical aspects of meta-analysis, this one-of-a-kind book applies the basic principles of sound data gathering to the task of producing a comprehensive assessment of existing research.
