Read and Download eBook Full
Author: Rolf-Dieter Wegner
Publisher: Springer Science & Business Media
Published: 2013-11-11
Total Pages: 464
ISBN-13: 3642599184
DOWNLOAD EBOOKFollowing a section on tissue culture, chromosome staining and basic information about karyotyping, this text presents nomenclature and quality standards, as well as protocols of relevance to comprehensive cytogenetic diagnostics.
Author: Robert Carachi
Publisher: Springer
Published: 2019-05-07
Total Pages: 482
ISBN-13: 3319261584
DOWNLOAD EBOOKThis comprehensive atlas is unique in combining information on the embryological development of the human with detailed presentation of the congenital malformations encountered in clinical practice. As a consequence it will not only assist practitioners and trainees in recognizing and evaluating malformations, but also enable them to understand how a malformation has developed and to explain the mystery of congenital malformations to relatives and patients. The book is organized according to anatomic region, with additional chapters on hernias, tumors, lymphogenesis and lymphatic malformations. According to WHO statistics, each year congenital anomalies result in approximately 3.2 million birth defect-related disabilities worldwide. All too often, however, training in embryology is now a neglected area, and medical graduates frequently lack confidence in their knowledge of the field. Clinical Embryology: An Atlas of Congenital Malformations will help to rectify this deficit and to ensure that malformations are comprehended and managed appropriately. It will be of value for postgraduate trainees in pediatric surgery, pediatrics, and neonatology, undergraduate medical students, and general practitioners/family physicians.
Author: Knut-Olaf Haustein
Publisher: Springer Science & Business Media
Published: 2013-03-14
Total Pages: 462
ISBN-13: 3662052563
DOWNLOAD EBOOK"Science tends to generalize, and generaliza tions mean simplifications . . . . And generaliza tions are also more satisfying to the mind than details. Of course, details and generalizations must be in proper balance: Generalizations can be reached only from details, while it is the generalization which gives value and interest to the detail:' . . . (A. Szent-Gyorgy, Science 1964) The first edition of this book, published in German as Tabak abhiingigkeit in 2001, was prompted by the fact that no single volume was available in Germany or elsewhere summarising the adverse repercussions of cigarette smoking on human health. As far as my own research was able to ascertain, the last comprehensive work dealing with this subject was writ ten in Germany by the Dresden internist, F. Lickint, whose Tabak und Organismus was published in 1939 by the Hip pokrates-Verlag. All subsequent monographs in this field have tended to focus on detailed aspects, and there has been no shortage of publications on subjects such as how smokers can quit smoking, healthy eating for smokers etc. Friends and colleagues abroad have urged me to prepare an English language version of Tabakabhiingigkeit. In gladly complying with this suggestion, I have intentionally prepared an up dated and slightly enlarged new edition, taking account of the rapidly proliferating literature on the subject up to the start of 2002. The harmful sequelae of smoking are played down by politicians in many industrialised countries, including Ger many.
Author: Karl H. Broer
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 357
ISBN-13: 3642609619
DOWNLOAD EBOOKIn the last few years rapid advances have been made in reproductive medicine, making it necessary for those involved to regularly update their knowledge. The purpose of this book is to describe the state of the art in this field, making it possible for the reader to gain an orientation among all the diagnostic and therapeutic potentials of modern reproductive medicine in order to advise patients fully. Chapters from the fields of gynecology, and reproductive medicine in a specific sense provide knowledge about these subjects. Authors of international standing have contributed chapters on their specialties. These chapters together form a book describing the state of the art in the diagnosis and therapy of sterility in gynecology and andrology.
Author: Daolin Tang
Publisher: Springer Nature
Published: 2019-10-10
Total Pages: 320
ISBN-13: 3030267806
DOWNLOAD EBOOKThis book sheds new light on ferroptosis, as an only recently recognised form of regulated cell death. Its respective chapters address the numerous implications that ferroptosis can have for virtually all aspects of metabolism. They also share insights on the morphological characterisation of ferroptosis and highlight the different pathways of induction. Accordingly, the book offers a unique perspective on a mechanism that is involved in a multitude of pathologies, including cancer cell death, neurotoxicity, neurodegenerative diseases, acute renal failure, drug-induced hepatotoxicity, tissue ischemia/reperfusion injury, and T cell immunity. Readers will learn in which cell types this form of regulated cell death is likely to occur, and how it can be pharmacologically influenced, making the book a fascinating and informative read not only for scientists working in cell biology, but also for clinicians in the field of cancer research.
Author: Shankar Vallabhajosula
Publisher: Springer Science & Business Media
Published: 2009-07-13
Total Pages: 379
ISBN-13: 3540767355
DOWNLOAD EBOOKRadioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Author: Walter K.H. Krause
Publisher: Springer
Published: 2016-11-02
Total Pages: 297
ISBN-13: 3319407880
DOWNLOAD EBOOKThis book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.
Author: Lutz Hein
Publisher: Springer Science & Business Media
Published: 2003-10-10
Total Pages: 692
ISBN-13: 9783540001096
DOWNLOAD EBOOKUp-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
Author: Elke Winterhager
Publisher: Springer Science & Business Media
Published: 2005-07-19
Total Pages: 312
ISBN-13: 9783540261568
DOWNLOAD EBOOKCommunication between cells via intercellular channels – gap junctions – appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility. Erroneous signaling mediated by the interaction of mutant connexins with other proteins, thought to be responsible for dysfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in both mice and men, is also addressed. Although the question of why some mutations in gap-junction proteins lead to specific phenotypes remains to be answered, the reviews in this book provide an intriguing insight into the future direction of this research field.
Author: Susan Mattson
Publisher: Saunders
Published: 1993
Total Pages: 820
ISBN-13:
DOWNLOAD EBOOKProvides basic and advanced coverage of maternal newborn nursing. Presented in outline format, coverage includes human reproduction, foetal growth and development, normal pregnancy, maternal-foetal well-being, psychosocial and physiological aspects of pregnancy and complications of childbearing.
