Mechanics and Energetics of Biological Transport
Mechanics and Energetics of Biological Transport

Author: E. Heinz

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 173

ISBN-13: 3642812597

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This book deals with energetics of transport processes, largely expressed in terms of the thermodynamics of irreversible pro cesses. Since at the present time too little is known about the molecular mechanism of transport, the present treatment is based largely on hypothetical models. Care has been taken, however, to define the crucial features of these models as generally as pos sible, so that the equations do not depend too much on hypotheti cal details. Accordingly, most equations, though developed on the basis of a mobile carrier (ferryboat) model, should apply equally to a conformational model, with an appropriate reinterpretation of the symbols. To better elucidate the essentials, the models are greatly simplified by special assumptions. Maximally, only two flows are assumed to be present in each model at one time: e. g. , two solute flows, the flow of solvent and of one solute, the flow of solvent and of heat. The simplifying assumptions may often be unreal. Hence the equations should not be applied un critically to actual mechanisms. They may at best serve as a ba sis on which the more appropriate equations may be developed. The book is not designed to give a complete kinetic analysis of the transport processes described. The kinetic equations are kept to the minimum required to describe the model concerned and to relate it to the corresponding thermodynamic equations. The in tention is to stress the close relationship between bioosmotic (transport) and biochemical processes in metabolism.

Principles and Models of Biological Transport
Principles and Models of Biological Transport

Author: Morton H. Friedman

Publisher: Springer Science & Business Media

Published: 2008-12-15

Total Pages: 520

ISBN-13: 0387792406

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Focus, Organization, and Content This book, like the first edition, deals with the mass transport processes that take place in living systems, with a focus on the normal behavior of eukaryotic cells and the - ganisms they constitute, in their normal physiological environment. As a consequence of this focus, the structure and content of the book differ from those of traditional transport texts. We do not start with the engineering principles of mass transport (which are well presented elsewhere) and then seek biological applications of these principles; rather, we begin with the biological processes themselves, and then - velop the models and analytical tools that are needed to describe them. This approach has several consequences. First of all, it drives the content of the text in a direction distinctively different from conventional transport texts. This is - cause the tools and models needed to describe complex biological processes are often different from those employed to describe more well-characterized inanimate systems. Many biological processes must still be described phenomenologically, using me- odologies like nonequilibrium thermodynamics. Simple electrical analogs employing a paucity of parameters can be more useful for characterization and prediction than complex theories based on the behavior of more well-defined systems on a laboratory bench. By allowing the biology to drive the choice of analysis tools and models, the latter are consistently presented in the context of real biological systems, and analysis and biology are interwoven throughout.

Molecular Mechanisms of Water Transport Across Biological Membranes
Molecular Mechanisms of Water Transport Across Biological Membranes

Author: Wilfred D. Stein

Publisher: Gulf Professional Publishing

Published: 2002-04-02

Total Pages: 472

ISBN-13: 9780123646194

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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume looks at water movements from a wide range of levels. It examines how water interacts with the major components of the cell, including proteins and lipids. It discusses how water moves across cell membranes by diffusion, how it is chanelled across these membranes or, in certain cases, pumped across, and how water movements are controlled. This book demonstrates how water and ion movements are closely linked in order to provide a better understanding of their behavior. *Essential Physical chemistry of water at biological interfaces *Up-to-date reviews of water behavior in cells *Water in integrated systems *Current information on water channels across membranes

Proteins
Proteins

Author: David M. Leitner

Publisher: CRC Press

Published: 2009-09-28

Total Pages: 450

ISBN-13: 1420087045

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Computational modeling can provide a wealth of insight into how energy flow in proteins mediates protein function. Computational methods can also address fundamental questions related to molecular signaling and energy flow in proteins. Proteins: Energy, Heat and Signal Flow presents state-of-the-art computational strategies for studying energy redi

Energy Transduction in Biological Membranes
Energy Transduction in Biological Membranes

Author: William A. Cramer

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 553

ISBN-13: 1461232201

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Energy Transduction in Biological Membranes was primarily designed for graduate courses in bioenergetics. Not only does it discuss basic principles and concepts central to modern membrane biochemistry, biophysics and molecular biology, but also (1) the components and pathways for electron transport and hydrogen ion translocation, and (2) the utilization of electrochemical ion gradients. The book is unique in presenting a comparative treatment of respiratory and photosynthetic energy transduction, and in using protein sequence data coupled with physical concepts to discuss the mechanisms of energy transducing proteins.

Membrane Structure and Mechanisms of Biological Energy Transduction
Membrane Structure and Mechanisms of Biological Energy Transduction

Author: J. Avery

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 596

ISBN-13: 146842016X

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The problem of electron transfer phosphorylation was first formu lated in 1939 by Belitser and Tsibakova I who introduced the "P: 0" criterion and showed that this ratio is more than 1. The authors noted that such a high value of the phosphorylation coefficient suggests a fundamental difference in the mechanisms of A TP formation coupled with respiration, and glycolysis, since in the latter case, the amount of the ATP synthesized is equal to that of the substrate utilized. A lot of hypothetical schemes were put forward to explain the nature of coupling between electron transfer and phosphorylation, but none of them solved the problem. Only quite recently, one hypo thetical scheme of energy coupling, viz. Mitchell's chemiosmotic concept, 2.3 was supported by experimental data which allow us to prefer it to alternative possibilities. In this paper, I shall try to substantiate the statement that oxidation and phosphorylation can be coupled via a membrane potential as was postulated by Mitchell.

Transport Processes in Eukaryotic and Prokaryotic Organisms
Transport Processes in Eukaryotic and Prokaryotic Organisms

Author: W.N. Konings

Publisher: Elsevier

Published: 1996-09-11

Total Pages: 957

ISBN-13: 0080543219

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In recent years it has become evident that transport processes across membranes play a crucial role in many metabolic systems. The activities of these transport processes often determine the physiology of the organisms.This book presents a state of the art review on the analysis of a wide variety of transport systems from bacteria and eukaryotic cells. A selection has been made of those systems that have been studied at the molecular level with special emphasis paid to the energetic and other biophysical properties. The different classes of transport systems are presented in the following: primary transport, secondary transport, phosphotransferase systems, channels and porines and macromolecular transport. Within each class of transporters several systems are presented by the leading experts in the field, which has resulted in a very broad overview of transport processes in biological cells. In this way the differences in the mechanisms used for translocation become evident while on the other hand features common to the different transport systems are revealed.