This second open access volume of the handbook series deals with detectors, large experimental facilities and data handling, both for accelerator and non-accelerator based experiments. It also covers applications in medicine and life sciences. A joint CERN-Springer initiative, the "Particle Physics Reference Library" provides revised and updated contributions based on previously published material in the well-known Landolt-Boernstein series on particle physics, accelerators and detectors (volumes 21A, B1,B2,C), which took stock of the field approximately one decade ago. Central to this new initiative is publication under full open access
This computer-based laboratory manual contains experiments in mechanics, thermodynamics, E&M, and optics using hardware and software designed to enhance readers' understanding of calculus-based physics concepts. The manual makes use of an active learning cycle, including concept overviews, hypothesis-testing, prediction-making, and investigations.
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
The twelfth-century French poet Chrétien de Troyes is a major figure in European literature. His courtly romances fathered the Arthurian tradition and influenced countless other poets in England as well as on the continent. Yet because of the difficulty of capturing his swift-moving style in translation, English-speaking audiences are largely unfamiliar with the pleasures of reading his poems. Now, for the first time, an experienced translator of medieval verse who is himself a poet provides a translation of Chrétien’s major poem, Yvain, in verse that fully and satisfyingly captures the movement, the sense, and the spirit of the Old French original. Yvain is a courtly romance with a moral tenor; it is ironic and sometimes bawdy; the poetry is crisp and vivid. In addition, the psychological and the socio-historical perceptions of the poem are of profound literary and historical importance, for it evokes the emotions and the values of a flourishing, vibrant medieval past.
This graduate-level text is based on a course in advanced quantum mechanics, taught many times at the University of Massachusetts, Amherst. Topics include propagator methods, scattering theory, charged particle interactions, alternate approximate methods, and Klein-Gordon and Dirac equations. Problems appear in the flow of the discussion, rather than at the end of chapters. 1992 edition.
