This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning), and discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods of the toxins, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effect of these toxins on public health.
Recent Advances in the Analysis of Marine Toxins, Volume 78, the newest release in the Comprehensive Analytical Chemistry series, presents chapters from the best authors in the field, making it an essential resource. Updated sections in this new volume include topics such as The importance of toxin detection and quantification: environmental issues, public health, food safety, animal health, bioterrorism, bioactive compounds, medical approach, an LC-MS/MS analysis of marine toxins, Animal bioassays: identification of toxins and mechanism of action, Receptor binding assays for the analysis of marine toxins, Immunoassays and optical biosensors (visual, SPR, fluorescence) for marine toxins, and Electrochemical biosensors for marine toxins. Chapters in this ongoing series contain practical and useful information, describing real advantages and limitations. Experts in this field contribute based on their research and personal point-of-view. - Contains contributions from the best authors in the field - Provides an essential resource for marine monitoring managers and scientific community
The occurrence of marine and freshwater toxins is a rapidly evolving problem due to ever-changing circumstances. Expanding international commerce is forcing cargo ships into virgin territory, deforestation and pollution violate the natural ecological balance, and a changing climate holds unknown potential to alter current factors and trigger toxic blooms in new forms, at new rates, and in new places. Fortunately, with notable advances in analysis technology, the body of knowledge in the field is equally dynamic. In just six years since the first edition, toxins that warranted only line listings, including pfiestra, gambierol, and polycavernoside, are now worthy of entire chapters, requiring a new edition to encompass the expanding scope of the field. Emphasizes Human Response to New Toxins Gathering contributions from international experts, Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Second Edition provides an overview of the current state-of-knowledge from several perspectives. Incorporating toxicology, chemistry, ecology, and economics, the book covers the biological aspects of the bloom and the effects and actions of each toxin with emphasis on human response. This edition includes more information on detection and analysis, toxicological information on previously little known toxins, and food safety issues. Incorporating Pharmacological, Legal, and Economic Aspects, this book— Begins with general information on risk assessment and analytical techniques Cover several categories of toxins by function and biomechanism Considers potential pharmacological applications and the use of toxins as precursors to therapeutic drugs Highlights the legal and economic perspectives of toxic incidence in industrial activity and international regulation and monitoring programs Describes new toxins by their individual chemical structure, ecobiology, metabolism, detection methods, determination, pharmacology, and toxicology
Harmful Algal Blooms: A Compendium Desk Reference erläutert die Grundlagen der schädlichen Algenblüte (HAB) und bietet die notwendigen technischen Informationen, wenn es um unerwartete oder unbekannte schädliche Ereignisse in Zusammenhang mit Algen geht. Dieses Fachbuch behandelt die Gründe für die schädliche Algenblüte, erfolgreiche Management- und Monitoring-Programme, Kontroll-, Präventions- und Minderungsstrategien, die wirtschaftlichen Folgen, Gesundheitsrisiken sowie die Folgen für die Nahrungskette und Ökosysteme. Darüber hinaus bietet es ausführliche Informationen zu den häufigsten HAB-Arten. Harmful Algal Blooms: A Compendium Desk Reference ist ein unschätzbares Referenzwerk für Manager, Einsteiger in das Fachgebiet, Praktiker mit eingeschränkten Zugang zu wissenschaftlicher Literatur und alle, die schnell Zugriff auf Informationen benötigen, insbesondere vor dem Hintergrund neuartiger oder unerwarteter HAB-Ereignisse. Die drei Herausgeber gehören zu den weltweit führenden Forschern auf dem Fachgebiet. Führende Experten haben ebenfalls zu diesem Fachbuch beigetragen, das sich zu einem wichtigen Referenzwerk des Fachgebiets entwickeln wird, zumal das Thema immer mehr an Bedeutung gewinnt.
Extensively revised and updated, Handbook of Water Analysis, Second Edition provides current analytical techniques for detecting compounds in water samples. Maintaining the detailed and accessible style of the original, this edition demonstrates water sampling and preservation methods by enumerating different ways to measure chemical and radiologic
Food safety is important and consumers have a right to expect that those who supply the food that they buy have taken every care to manufacture products that will do them no harm. Those with a responsibility for the regulation of the global food industry recognise this principle and legislate accordingly and the business of managing and regulating the safety of the food supply chain has come a long way in the last 25 years or so. Prompted by the emergence of new food safety hazards, such as the bacterial pathogens Listeria monocytogenes and E. coli O157, powerful new techniques for evaluating and managing the risks presented by these threats have been developed. For example, hazard analysis critical control point, or HACCP, has now become the food safety management system of choice worldwide. Although the food safety management tools are now widely available, they are still virtually useless unless they are supported by adequate and accurate information. HACCP does not work unless its practitioners have access to enough data and scientific knowledge to enable them to understand hazards and how to control them effectively. The Food Safety Hazard Guidebook is an attempt to address the problem of accessing the available information by distilling the key facts about a wide range of individual food safety hazards into a single text. The result is a guidebook, rather than an encyclopaedia, which acts as a portal for the immense and ever expanding body of scientific knowledge that exists for food safety. It is an easy-to-use information resource for anyone with a professional interest in the safety of the food supply. The book is easy to navigate and presents concise and carefully researched factual information on a wide range of biological and chemical hazards in a clear format that is designed to support risk analysis exercises and HACCP studies. It covers a broad range of established and emerging food safety hazards and includes details of authoritative sources of further information (many web-based) for those seeking to examine a topic in greater depth. The section on food allergens is a particularly valuable component of the book, the chapters on fish toxins are also useful and unusual in a book of this kind and bacterial pathogens are comprehensively covered. One of the most important features of the book is the wide scope of the content and the highly structured format designed to help the reader find information quickly. Other key benefits to the reader are: -The wide range of biological and chemical hazards covered in a single book -Written specifically with food industry professionals in mind -Easy to navigate and accessible for the non-expert -Clear and concise presentation of factual information presented in a format that lends itself to use in risk assessment exercises -Inclusion of references and web links to reliable sources of further information on each chapter -specifically designed for practical use by a professional readership.
Phycotoxins: Chemistry and Biochemistry presents the most updated information available on phycotoxins. Major emphases are given to chemistry and biochemistry, while minor emphases are given to the aspects of origin, toxicology, or analytical methodology. The book discusses 16 phycotoxins, 7 on those affecting the nervous systems, 4 affecting other body systems; and 4 with undefined targets. An alphabetical listing of toxins presented includes: Azaspiracids; Brevetoxins; Cyanobacterial toxins; Domoic acid; Gambierols; Gymnodimines, prorocentrolides, spirolides, pinnatoxins and cyclic imines in general; Maitotoxin; Okadaic acid and dinophysistoxins; Palytoxins and ostreocins; Pectenotoxins; Polycavernosides; and Yessotoxins. In addition, several mechanistic aspects of newer or emerging toxins are covered such as amphidinols or gymnocine. Information presented and coverage of each toxin follows the following distribution: background and toxicology (10%); chemistry, biochemistry and metabolism (75%); mechanism of action (10%); and analytical methodology (5%). The detailed information on chemistry in Phycotoxins: Chemistry and Biochemistry provides investigators, regulators, food technologists and toxicologists an updated basis on which research in other areas such as toxicology, mechanism of action, analytical methodology and pharmacology can be successfully developed and expanded.
This book provides a structured account of the existing knowledge of toxic algae, the chemistry of the toxins they produce, the effects these substances exert in humans and wildlife, as well as the strategies envisaged to protect public health and the environment. It covers recent advances in the understanding of the biology of toxin producers and
Written by world government and industry experts, this book focuses on the application of new seafood inspection systems that ensure the public health while providing a reasonable environment for business. International trade has experienced very dynamic developments over the last few years, including new international trade agreements and new approaches in food safety inspection. The focus has shifted from traditional end product inspection to modern, preventive methods. Covering all aspects of the industry, Fish Inspection, Quality Control, and HACCP: A Global Focus aids readers in providing the safest possible high quality seafood to the ever-demanding public.
