Marine Natural Products: Chemical and Biological Perspectives, Volume I, reviews the state of knowledge in the chemistry and biology of marine natural products. It brings together critical reviews and new perspectives for the marine research community. The book's opening chapter discusses the isolation, distribution, chemistry, pharmacology, and public health aspects of dinoflagellate toxins. This is followed by separate chapters on algal nonisoprenoids, algal sesquiterpenoids, terpenoids from marine sponges, and uncommon marine steroids.
Marine Natural Products: Chemical and Biological Perspectives, Volume I, reviews the state of knowledge in the chemistry and biology of marine natural products. It brings together critical reviews and new perspectives for the marine research community. The book's opening chapter discusses the isolation, distribution, chemistry, pharmacology, and public health aspects of dinoflagellate toxins. This is followed by separate chapters on algal nonisoprenoids, algal sesquiterpenoids, terpenoids from marine sponges, and uncommon marine steroids.
Marine Natural Products: Chemical and Biological Perspectives, Volume III, reviews the state of knowledge in the chemistry and biology of marine natural products. It attempts to bring together timely and critical reviews that are representative of major current researches and that, hopefully, will also foreshadow future trends. The volume's first chapter discusses separation techniques, including liquid-liquid extraction, membrane separation, chromatography, capillary gas chromatography, and high-performance liquid chromatography. This is followed by a chapter on amino acids that have been isolated from marine algae. Kainic acid, for instance, is a well-established ascaricide that was isolated from a red alga that had been known as an anthelmintic for a thousand years. Only recently, however, has it been recognized as a valuable tool in neurophy sinology. Subsequent chapters deal with nitrogenous pigments in marine invertebrates; and the phenomenon of bioluminescence, which is relatively rare among terrestrial organisms, but which is widespread among marine biota.
In recent years, marine genomics has become a rapidly growing field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled “Genome Mining and Synthetic Biology in Marine Natural Product Discovery” aims to to assess the impact of these molecular approaches on the discovery of bioactive compounds from marine organisms. The term “genome mining” is used to identify all bioinformatic investigations aimed at detecting the biosynthetic pathways of bioactive natural products and their possible functional and chemical interactions. Several studies are now reporting on marine organisms. Oceans cover nearly 70% of the Earth’s surface and host a huge ecological, chemical, and biological diversity. The natural conditions of the sea favor, in marine organisms, the production of a large variety of novel molecules with great pharmaceutical potential. Marine organisms are unique in their structural and functional features compared to terrestrial ones. Innovation in this field is very rapid, as revealed by the funding of several Seventh Framework Programme (FP7) and Horizon 2020 projects under the topic “Blue Growth”, with the urgent goal of discovering new drugs.
The first of its kind, this dictionary defines more than 25,000 marine- natural products. It indexes each by chemical name, organism type, and compound type. Following a similar format to the Chapman & Hall Chemical Database, each entry includes biological source, chemical structure, physical properties, biological activity, and literature references. With an accompanying CD, this invaluable tool offers immediate access to information essential to the development of novel pharmaceuticals, pesticides, and marine anti-fouling agents derived from unique molecular structures of marine natural products.
Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.
Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. Volume seven of the series brings seven reviews covering these topics: - Plant-Derived Anticancer Compounds Used in Cancer Therapies - Pradimicin and Benanomicin Antibiotics - The Chemical Compositions of Bixa orellana and their Pharmacological Activities - Overview of Phytochemistry and Pharmacology of Nilakanthi (Ajuga bracteosa Wall. ex Benth.) - Tetracyclic benzocarbazoles and derivatives - Chalcones as Antiinflammatory, Antidiabetic, and Antidepressant Agents - Bioactive Steroids from Marine Organisms
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents exciting sources of new pharmacophores
Marine Natural Products: Chemical and Biological Perspectives, Volume III, reviews the state of knowledge in the chemistry and biology of marine natural products. It attempts to bring together timely and critical reviews that are representative of major current researches and that, hopefully, will also foreshadow future trends. The volume's first chapter discusses separation techniques, including liquid-liquid extraction, membrane separation, chromatography, capillary gas chromatography, and high-performance liquid chromatography. This is followed by a chapter on amino acids that have been isolated from marine algae. Kainic acid, for instance, is a well-established ascaricide that was isolated from a red alga that had been known as an anthelmintic for a thousand years. Only recently, however, has it been recognized as a valuable tool in neurophy sinology. Subsequent chapters deal with nitrogenous pigments in marine invertebrates; and the phenomenon of bioluminescence, which is relatively rare among terrestrial organisms, but which is widespread among marine biota.
