Management of Dysregulated Immune Response in the Critically Ill
Management of Dysregulated Immune Response in the Critically Ill

Author: Zsolt Molnar

Publisher: Springer Nature

Published: 2023-03-11

Total Pages: 325

ISBN-13: 3031175727

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This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs.

Immune Response in the Critically Ill
Immune Response in the Critically Ill

Author: John C. Marshall

Publisher: Springer Science & Business Media

Published: 2002-01-21

Total Pages: 458

ISBN-13: 9783540425892

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This book brings together basic scientists or clinicians from a variety of different backgrounds - immunology, infectious diseases or critical care - who share a common interest in understanding the changes that occur in immune responses in sepsis. It provides an up-to-date and unrivalled synthesis of current research in this rapidly developing field.

Stress Challenges and Immunity in Space
Stress Challenges and Immunity in Space

Author: Alexander Choukèr

Publisher: Springer

Published: 2020-12-03

Total Pages: 0

ISBN-13: 9783030169985

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This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Post-Intensive Care Syndrome
Post-Intensive Care Syndrome

Author: Jean-Charles Preiser

Publisher: Springer Nature

Published: 2019-08-31

Total Pages: 374

ISBN-13: 3030242501

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This book, part of the European Society of Intensive Care Medicine textbook series, provides detailed up-to-date information on the physical, cognitive, and psychological impairments that are frequently present following a stay in an intensive care unit and examines in depth the available preventive and therapeutic strategies, including adapted rehabilitation programs. Beyond acquainting readers with the multiple facets of post-intensive care syndrome (PICS), the book aims to promote the effective follow-up of patients, thereby enhancing their ability to work and their functional autonomy, and to identify risk factors for the development of PICS as a stimulus to beneficial organizational changes in intensive care departments. The background to the book is the realization by healthcare providers that the quality of life of patients who have required a stay in an intensive care unit can be severely impaired or even become unacceptable. All too often, the diverse sequelae are overlooked by specialists of other disciplines. Moreover, families and caregivers are also at high risk of post-traumatic stress disorder and depression. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. This book, written by renowned experts in the field, will facilitate the transmission of key knowledge with significant clinical and financial benefits.

Sepsis Management in Resource-limited Settings
Sepsis Management in Resource-limited Settings

Author: Arjen M. Dondorp

Publisher: Springer

Published: 2019-02-08

Total Pages: 226

ISBN-13: 3030031438

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This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients
Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

Author: Nicola Vargas

Publisher: Springer Nature

Published: 2020-08-25

Total Pages: 206

ISBN-13: 3030556212

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This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the Covid-19 pandemic, and offers practical information on how to manage them. Older adults are more susceptible to complications such as acute respiratory distress syndrome (ARDS) as a result of viral pneumonia. In addition, they often have multiple comorbidities and are commonly frail, which means their various organs and systems, such as the respiratory system, have reduced functional reserves. As such, older adults are less able to react to acute stressors. During the current Covid-19 pandemic, older adult patients' mortality is increased. Further, the infection and death rates of elderly people in nursing homes and health care institutions are high. Management of older adults with Covid is complicated. The reduced availability of beds may limit their access to ICU. Moreover, the prognosis may be poor, and airway management and ventilation strategies have to take into account various clinical and physiological characteristics specific to older patients. This book is addressed to all allied professionals involved in the management of older critically ill patients and presents information collected and practical lessons learned from the clinical daily management of this population during the pandemic.

Medical Immunology
Medical Immunology

Author: Gabriel Virella

Publisher: CRC Press

Published: 2007-03-28

Total Pages: 489

ISBN-13: 1420020870

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With an abundance of illustrations, diagrams, and algorithms, this sixth edition of Medical Immunology provides a reader-friendly review of critical material on the current diagnostic and clinical applications of immunology. Organized into four sections that describe clinical applications, methodological advances, immunological diseases, and innova

The Washington Manual of Critical Care
The Washington Manual of Critical Care

Author: Marin Kollef

Publisher: Lippincott Williams & Wilkins

Published: 2024-06-30

Total Pages: 989

ISBN-13: 197521546X

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Part of the popular Washington Manual® handbook series, The Washington Manual® of Critical Care provides concise, high-yield content that reflects today’s fast-changing advances in the field. Edited by Drs. Marin H. Kollef, Vladimir N. Despotovic, Bryan D. Kraft, Rachel K. McDonald, and Nguyet Nguyen, and written by teams of Washington University residents and faculty, the fourth edition focuses on the essential information you need to know, using a brief, bulleted format, along with numerous figures, tables, algorithms, and images throughout. In one convenient, portable resource, you’ll find complete coverage of bedside diagnosis and management of the most frequently encountered illnesses and problems seen in the ICU—all at your fingertips for quick review and reference.

New Strategies for Treatment of Sepsis
New Strategies for Treatment of Sepsis

Author: Antonio Mirijello

Publisher: Mdpi AG

Published: 2021-12-27

Total Pages: 146

ISBN-13: 9783036524832

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This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.

Annual Update in Intensive Care and Emergency Medicine 2021
Annual Update in Intensive Care and Emergency Medicine 2021

Author: Jean-Louis Vincent

Publisher: Springer Nature

Published: 2021-09-03

Total Pages: 301

ISBN-13: 3030732312

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The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.