Macromolecular Crystallography, Part C
Macromolecular Crystallography, Part C

Author: Charles W. Carter Jr.

Publisher: Elsevier

Published: 2003-12-15

Total Pages: 405

ISBN-13: 0080497098

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Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.* Methodological methods in crystals* Methodological methods data analysis

The Unfolded Protein Response and Cellular Stress, Part C
The Unfolded Protein Response and Cellular Stress, Part C

Author:

Publisher: Academic Press

Published: 2011-02-14

Total Pages: 465

ISBN-13: 0123859298

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This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights - This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation - The authors explain how these methods are able to provide important biological insights

Amyloid, Prions, and Other Protein Aggregates, Part C
Amyloid, Prions, and Other Protein Aggregates, Part C

Author:

Publisher: Elsevier

Published: 2006-10-06

Total Pages: 412

ISBN-13: 0080468977

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The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part B (volume 412) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. - Presents detailed protocols - Includes troubleshooting tips - Provides coverage on structural biology, computational methods, and biology

Macromolecular Crystallography
Macromolecular Crystallography

Author: Charles W. Carter

Publisher: Gulf Professional Publishing

Published: 1997

Total Pages: 754

ISBN-13: 9780121827779

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Annotation Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Phases * Map interpretation and refinement * Analysis and software.

Neutron Crystallography in Structural Biology
Neutron Crystallography in Structural Biology

Author:

Publisher: Academic Press

Published: 2020-02-24

Total Pages: 408

ISBN-13: 0128192143

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Neutron Crystallography in Structural Biology, Volume 634, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this updated release include Fundamentals of neutron crystallography in structural biology, Large crystal growth for neutron protein crystallography, Prospects for membrane protein crystals in NMX, IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor, The macromolecular neutron diffractometer at the spallation neutron source, Current status and near future plan of neutron protein crystallography at J-PARC, Neutron macromolecular crystallography at the European spallation source, and much more.

Energetics of Biological Macromolecules, Part C
Energetics of Biological Macromolecules, Part C

Author:

Publisher: Elsevier

Published: 2000-08-09

Total Pages: 581

ISBN-13: 0080496784

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Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal is to understand the energetic relationships between macromoleculer structures and biological functions. This volume supplements Volumes 259 and Volume 295 of Methods in Enzymology.Key Features* Probing Stability of Helical Transmembrane Proteins* Energetics of Vinca Alkaloid Interactions with Tubulin* Deriving Complex Ligand Binding Formulas* Mathematical Modeling of Cooperative Interactions in Hemoglobin* Analysis of Interactions of Regulatory Protein TyrR with DNA* Parsing Free Energy of Drug-DNA Interactions* Use of Fluorescence as Thermodynamics Tool

Applications of Chimeric Genes and Hybrid Proteins, Part C: Protein-Protein Interactions and Genomics
Applications of Chimeric Genes and Hybrid Proteins, Part C: Protein-Protein Interactions and Genomics

Author:

Publisher: Elsevier

Published: 2000-10-28

Total Pages: 701

ISBN-13: 0080496830

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Nanomedicine
Nanomedicine

Author:

Publisher: Academic Press

Published: 2012-12-31

Total Pages: 475

ISBN-13: 0123918707

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This volume in the Methods in Enzymology series comprehensively covers Infectious Diseases, Immunotheraphy, Gene Medicine, Diagnostics and Toxicology of Nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine toxicity, and Diagnostic Nanomedicine. - Comprehensively covers infectious diseases, immunotherapy, gene medicine, diagnostics, and toxicology of nanomedicine - International board of authors - Split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine Toxicity, and Diagnostic Nanomedicine

Nanomedicine
Nanomedicine

Author: Nejat Duzgunes

Publisher: Academic Press

Published: 2012-03-30

Total Pages: 503

ISBN-13: 012391860X

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This volume comprehensively covers cancer, cardiovascular and the central nervous system of nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as diabetes and nanotechnology as potential therapy, and nanomedicines for inflammatory diseases.

Methods in Systems Biology
Methods in Systems Biology

Author: Daniel Jameson

Publisher: Academic Press

Published: 2011-09-26

Total Pages: 775

ISBN-13: 0123851181

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Systems biology is a term used to describe a number of trends in bioscience research and a movement that draws on those trends. This volume in the Methods in Enzymology series comprehensively covers the methods in systems biology. With an international board of authors, this volume is split into sections that cover subjects such as machines for systems biology, protein production and quantification for systems biology, and enzymatic assays in systems biology research. This volume in the Methods in Enzymology series comprehensively covers the methods in systems biology With an international board of authors, this volume is split into sections that cover subjects such as machines for systems biology, protein production and quantification for systems biology, and enzymatic assays in systems biology research