Machine Learning in Single-Cell RNA-seq Data Analysis
Author: Khalid Raza
Publisher: Springer Nature
Published:
Total Pages: 104
ISBN-13: 9819767032
DOWNLOAD EBOOKRead and Download eBook Full
Author: Khalid Raza
Publisher: Springer Nature
Published:
Total Pages: 104
ISBN-13: 9819767032
DOWNLOAD EBOOKAuthor: William L. William L. Hamilton
Publisher: Springer Nature
Published: 2022-06-01
Total Pages: 141
ISBN-13: 3031015886
DOWNLOAD EBOOKGraph-structured data is ubiquitous throughout the natural and social sciences, from telecommunication networks to quantum chemistry. Building relational inductive biases into deep learning architectures is crucial for creating systems that can learn, reason, and generalize from this kind of data. Recent years have seen a surge in research on graph representation learning, including techniques for deep graph embeddings, generalizations of convolutional neural networks to graph-structured data, and neural message-passing approaches inspired by belief propagation. These advances in graph representation learning have led to new state-of-the-art results in numerous domains, including chemical synthesis, 3D vision, recommender systems, question answering, and social network analysis. This book provides a synthesis and overview of graph representation learning. It begins with a discussion of the goals of graph representation learning as well as key methodological foundations in graph theory and network analysis. Following this, the book introduces and reviews methods for learning node embeddings, including random-walk-based methods and applications to knowledge graphs. It then provides a technical synthesis and introduction to the highly successful graph neural network (GNN) formalism, which has become a dominant and fast-growing paradigm for deep learning with graph data. The book concludes with a synthesis of recent advancements in deep generative models for graphs—a nascent but quickly growing subset of graph representation learning.
Author: Gabriel Peyre
Publisher: Foundations and Trends(r) in M
Published: 2019-02-12
Total Pages: 272
ISBN-13: 9781680835502
DOWNLOAD EBOOKThe goal of Optimal Transport (OT) is to define geometric tools that are useful to compare probability distributions. Their use dates back to 1781. Recent years have witnessed a new revolution in the spread of OT, thanks to the emergence of approximate solvers that can scale to sizes and dimensions that are relevant to data sciences. Thanks to this newfound scalability, OT is being increasingly used to unlock various problems in imaging sciences (such as color or texture processing), computer vision and graphics (for shape manipulation) or machine learning (for regression, classification and density fitting). This monograph reviews OT with a bias toward numerical methods and their applications in data sciences, and sheds lights on the theoretical properties of OT that make it particularly useful for some of these applications. Computational Optimal Transport presents an overview of the main theoretical insights that support the practical effectiveness of OT before explaining how to turn these insights into fast computational schemes. Written for readers at all levels, the authors provide descriptions of foundational theory at two-levels. Generally accessible to all readers, more advanced readers can read the specially identified more general mathematical expositions of optimal transport tailored for discrete measures. Furthermore, several chapters deal with the interplay between continuous and discrete measures, and are thus targeting a more mathematically-inclined audience. This monograph will be a valuable reference for researchers and students wishing to get a thorough understanding of Computational Optimal Transport, a mathematical gem at the interface of probability, analysis and optimization.
Author:
Publisher: Academic Press
Published: 2020-01-28
Total Pages: 586
ISBN-13: 0128186755
DOWNLOAD EBOOKTumor Immunology and Immunotherapy - Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more.
Author: Guo-Cheng Yuan
Publisher: Humana Press
Published: 2019-02-14
Total Pages: 271
ISBN-13: 9781493990566
DOWNLOAD EBOOKThis detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis.
Author: Eija Korpelainen
Publisher: CRC Press
Published: 2014-09-19
Total Pages: 314
ISBN-13: 1466595019
DOWNLOAD EBOOKThe State of the Art in Transcriptome AnalysisRNA sequencing (RNA-seq) data offers unprecedented information about the transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. RNA-seq Data Analysis: A Practical Approach enables researchers to examine differential expression at gene, exon, and transcript le
Author: Nilanjan Dey
Publisher: Springer
Published: 2017-11-10
Total Pages: 453
ISBN-13: 3319659812
DOWNLOAD EBOOKThis book on classification in biomedical image applications presents original and valuable research work on advances in this field, which covers the taxonomy of both supervised and unsupervised models, standards, algorithms, applications and challenges. Further, the book highlights recent scientific research on artificial neural networks in biomedical applications, addressing the fundamentals of artificial neural networks, support vector machines and other advanced classifiers, as well as their design and optimization. In addition to exploring recent endeavours in the multidisciplinary domain of sensors, the book introduces readers to basic definitions and features, signal filters and processing, biomedical sensors and automation of biomeasurement systems. The target audience includes researchers and students at engineering and medical schools, researchers and engineers in the biomedical industry, medical doctors and healthcare professionals.
Author: David J. Balding
Publisher: John Wiley & Sons
Published: 2019-07-09
Total Pages: 1740
ISBN-13: 1119429250
DOWNLOAD EBOOKA timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.
Author: Antonio Gulli
Publisher: Packt Publishing Ltd
Published: 2017-04-26
Total Pages: 310
ISBN-13: 1787129039
DOWNLOAD EBOOKGet to grips with the basics of Keras to implement fast and efficient deep-learning models About This Book Implement various deep-learning algorithms in Keras and see how deep-learning can be used in games See how various deep-learning models and practical use-cases can be implemented using Keras A practical, hands-on guide with real-world examples to give you a strong foundation in Keras Who This Book Is For If you are a data scientist with experience in machine learning or an AI programmer with some exposure to neural networks, you will find this book a useful entry point to deep-learning with Keras. A knowledge of Python is required for this book. What You Will Learn Optimize step-by-step functions on a large neural network using the Backpropagation Algorithm Fine-tune a neural network to improve the quality of results Use deep learning for image and audio processing Use Recursive Neural Tensor Networks (RNTNs) to outperform standard word embedding in special cases Identify problems for which Recurrent Neural Network (RNN) solutions are suitable Explore the process required to implement Autoencoders Evolve a deep neural network using reinforcement learning In Detail This book starts by introducing you to supervised learning algorithms such as simple linear regression, the classical multilayer perceptron and more sophisticated deep convolutional networks. You will also explore image processing with recognition of hand written digit images, classification of images into different categories, and advanced objects recognition with related image annotations. An example of identification of salient points for face detection is also provided. Next you will be introduced to Recurrent Networks, which are optimized for processing sequence data such as text, audio or time series. Following that, you will learn about unsupervised learning algorithms such as Autoencoders and the very popular Generative Adversarial Networks (GAN). You will also explore non-traditional uses of neural networks as Style Transfer. Finally, you will look at Reinforcement Learning and its application to AI game playing, another popular direction of research and application of neural networks. Style and approach This book is an easy-to-follow guide full of examples and real-world applications to help you gain an in-depth understanding of Keras. This book will showcase more than twenty working Deep Neural Networks coded in Python using Keras.
Author: Mark S. Handcock
Publisher: Springer Science & Business Media
Published: 2006-05-10
Total Pages: 272
ISBN-13: 0387226583
DOWNLOAD EBOOKThis monograph presents methods for full comparative distributional analysis based on the relative distribution. This provides a general integrated framework for analysis, a graphical component that simplifies exploratory data analysis and display, a statistically valid basis for the development of hypothesis-driven summary measures, and the potential for decomposition - enabling the examination of complex hypotheses regarding the origins of distributional changes within and between groups. Written for data analysts and those interested in measurement, the text can also serve as a textbook for a course on distributional methods.