Belle époque Paris adored dance. Whether at the music hall or in more refined theaters, audiences flocked to see the spectacles offered to them by the likes of Isadora Duncan, Diaghilev’s flashy company, and an embarrassment of Salomés. After languishing in the shadow of opera for much of the nineteenth century, ballet found itself part of this lively kinetic constellation. In Kinetic Cultures, Rachana Vajjhala argues that far from being mere delectation, ballet was implicated in the larger republican project of national rehabilitation through a rehabilitation of its citizens. By tracing the various gestural complexes of the period—bodybuilding routines, appropriate physical comportment for women, choreographic vocabularies, and more–-Vajjhala presents a new way of understanding histories of dance and music, one that she locates in gesture and movement.
This contributed volume is dedicated towards the progress achieved within the last years in all areas of Cell Culture Engineering and Technology. It comprises contributions of active researchers in the field of cell culture development for the production of recombinant proteins, cell line development, cell therapy and gene therapy, with consideration of media development, process scale-up, reactor design, monitoring and control and model-assisted strategies for process design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. This book is conceived for graduate students, postdoctoral fellows and researchers interested in the latest developments in Cell Engineering.
Cell Culture Engineering IV, Improvements of Human Health covers the latest approaches to improving the cell host through improved understanding of the molecular biology, the development of novel vaccines, approaches to bioreactor design and operation, monitoring techniques in process control and quality related topics. The work was carefully put together as one result of the Cell Culture Engineering IV Meeting held in San Diego, U.S.A. in 1994, however, the book may not be perceived as a proceedings volume - the criteria of the book series apply. For cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to cell culture engineering, working in the academic environment, as well as in (biotechnology or pharmaceutical) industry.
Regeneration of tissue to replace damaged or injured tissue is the goal of t- sue engineering. Biomaterials like polyglycolic acid, collagen and small-intestinal submuscosa provide a temporary scaffold to guide new tissue growth and or- nization. Typically, they need to be biodegradable, showing good cell atta- ment and proliferation and they should possess appropriate mechanical properties (Kim et al. , 2000). Synthetic polymers ful ll most of these requirements but lack cell-adhesion peptides on their surface to enhance cell attachment. Ce- adhesion peptides are present in ECM proteins like collagen and elastin. Thus a synthetic polymer coated with ECM proteins would result in a scaffold that mimics the natural cellular environment with enhanced cell attachment and p- liferation. The new bioactive scaffold will be made by combining a synthetic polymer coated with a layer of recombinant ECM proteins produced by CHO cells. The rst step consists of identifying polymers that give best results in terms of CHO cell attachment and growth. Classical techniques to determine biomass are inappropriate to evaluate 3-D structures. Thus a screening system based on stable GFP expressing CHO cells was used to compare the different scaffolds. Simple uorescent measurement after cell lysis allows determining cell attachment and p- liferation on synthetic polymers. Finally CHO cells producing human recombinant collagen I and elastin were generated. We showed that both proteins are expressed and secreted by CHO DG44 cells. 2 Materials and Methods 2.
Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology devel
Tim Lewens aims to understand what it means to take an evolutionary approach to cultural change, and why it is that this approach is often treated with suspicion. Convinced of the exceptional power of natural selection, many thinkers—typically working in biological anthropology, cognitive psychology, and evolutionary biology—have suggested it should be freed from the confines of biology, and applied to cultural change in humans and other animals. At the same time, others—typically with backgrounds in disciplines like social anthropology and history—have been just as vocal in dismissing the evolutionary approach to culture. What drives these disputes over Darwinism in the social sciences? While making a case for the value of evolutionary thinking for students of culture, Lewens shows why the concerns of sceptics should not be dismissed as mere prejudice, confusion, or ignorance. Indeed, confusions about what evolutionary approaches entail are propagated by their proponents, as well as by their detractors. By taking seriously the problems faced by these approaches to culture, Lewens shows how such approaches can be better formulated, where their most significant limitations lie, and how the tools of cultural evolutionary thinking might become more widely accepted.
The first edition of this book was published in 2008 and it went on to become IWA Publishing’s bestseller. Clearly there was a need for it because over the twenty years prior to 2008, the knowledge and understanding of wastewater treatment had advanced extensively and moved away from empirically-based approaches to a fundamental first-principles approach based on chemistry, microbiology, physical and bioprocess engineering, mathematics and modelling. However the quantity, complexity and diversity of these new developments was overwhelming for young water professionals, particularly in developing countries without readily available access to advanced-level tertiary education courses in wastewater treatment. For a whole new generation of young scientists and engineers entering the wastewater treatment profession, this book assembled and integrated the postgraduate course material of a dozen or so professors from research groups around the world who have made significant contributions to the advances in wastewater treatment. This material had matured to the degree that it had been codified into mathematical models for simulation with computers. The first edition of the book offered, that upon completion of an in-depth study of its contents, the modern approach of modelling and simulation in wastewater treatment plant design and operation could be embraced with deeper insight, advanced knowledge and greater confidence, be it activated sludge, biological nitrogen and phosphorus removal, secondary settling tanks, or biofilm systems. However, the advances and developments in wastewater treatment have accelerated over the past 12 years since publication of the first edition. While all the chapters of the first edition have been updated to accommodate these advances and developments, some, such as granular sludge, membrane bioreactors, sulphur conversion-based bioprocesses and biofilm reactors which were new in 2008, have matured into new industry approaches and are also now included in this second edition. The target readership of this second edition remains the young water professionals, who will still be active in the field of protecting our precious water resources long after the aging professors who are leading some of these advances have retired. The authors, all still active in the field, are aware that cleaning dirty water has become more complex but that it is even more urgent now than 12 years ago, and offer this second edition to help the young water professionals engage with the scientific and bioprocess engineering principles of wastewater treatment science and technology with deeper insight, advanced knowledge and greater confidence built on stronger competence.
Addresses the accommodation of social equity with cultural diversity in educational terms. The book seeks to find the pathways to a less selfish and parochial response to the problem with new approaches and policies.
