Stem Cells

Stem Cells

Author: C. Potten

Publisher: Elsevier

Published: 1996-10-09

Total Pages: 497

ISBN-13: 0080541763

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Stem cells are relatively undifferentiated cells which are the permanent lineage ancestor cells of tissues. Newly developed molecular biological techniques and probes have made possible dramatic advances in our ability to study the lineage development of stem cells. A major impetus to develop these techniques has been to identify specific stem cells for gene therapy purposes. The role that stem cells play in the development of cancer is also an important area. This book provides up-to-date reviews on a wide variety of stem cell systems by world experts. Chapters range from descriptions of the current knowledge of the biology of stem cells, to current molecular biological approaches and clinical implications. Oncologists and cell biologists will find this book of particular interest. It will also be usefule to radiobiologist, biotechnologists, and gene therapists. - Provides reviews of stem cell systems by world experts - Covers stem cell biology in plants, invertebrates, and mammals - Presents clinical implications of stem cell differentiation


Stem Cell Biology and Tissue Engineering in Dental Sciences

Stem Cell Biology and Tissue Engineering in Dental Sciences

Author: Ajaykumar Vishwakarma

Publisher: Academic Press

Published: 2014-11-05

Total Pages: 933

ISBN-13: 0123977789

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Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. - Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization - Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology - Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine - Print book is available and black and white, and the ebook is in full color


Corneal Regeneration

Corneal Regeneration

Author: Jorge L. AliĆ³

Publisher: Springer

Published: 2019-02-20

Total Pages: 510

ISBN-13: 3030013049

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This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy. Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.


Therapy with Cultured Cells

Therapy with Cultured Cells

Author: Howard Green

Publisher: CRC Press

Published: 2019-05-08

Total Pages: 95

ISBN-13: 9814267716

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In this book the author describes the discoveries in his laboratory that led to therapy with cultured cells. The first cultured cell type used for therapy was the keratinocyte of the epidermis, for the treatment of burns. Subsequent developments led to the use of cultured cells for the treatment of diseases of the eye, of the joints and of other diseases. Cultured cells for therapy are now being prepared by industries in the US, Japan and Korea and are used in the aforesaid countries, as well as in France, Sweden and Greece, for the treatment of disease.


The Keratinocyte Handbook

The Keratinocyte Handbook

Author:

Publisher: CUP Archive

Published: 1994

Total Pages: 228

ISBN-13: 9780521450133

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"Keratinocytes, as the main cellular component of the organism/environment interface, perform a vast range of functions in protection, secretion, sensation and self-repair by virtue of their great plasticity in form and development. Indeed recent medical advances in laboratory culture of these cells for use as skin grafts in cases of severe burns or ulceration owe much of their success to this very plasticity. Drawing upon a wide range of international expertise the various interconnected aspects of cell structure, composition and function are laid out in this volume, providing a comprehensive dossier of the keratinocyte and its biological significance."--Pub. desc.


Equine Dermatology - E-Book

Equine Dermatology - E-Book

Author: Danny W. Scott

Publisher: Elsevier Health Sciences

Published: 2010-12-20

Total Pages: 551

ISBN-13: 1437709214

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Diagnose, treat, and manage equine skin disorders with the most comprehensive reference available! With 900 full-color photos, Equine Dermatology covers skin diseases ranging from those that merely annoy the horse to others that interfere with the horse's ability to function in riding, working, or show. Thorough coverage includes essential basics and practical diagnostic methods, therapies, and specific abnormalities and defects. The book describes the structure and function of the skin, and discusses disorders including bacterial, fungal, parasitic, viral, protozoal, allergic, immune-mediated, endocrine, metabolic, and nutritional diseases. It also covers congenital and hereditary defects, pigmentation abnormalities, keratinization defects, environmental skin diseases, and skin tumors. Written by renowned equine dermatologists Danny Scott and Bill Miller, this all-inclusive resource covers the latest dermatologic topics and the newest therapies. - Current, comprehensive coverage includes every known equine dermatosis. - An emphasis on differential diagnosis includes key differentials and breed predilections for each disease, especially helpful when you have only a specimen and an incomplete history to work with. - A consistent format makes it easy to locate information on each skin disorder, including a clinical description, its cause and pathogenesis, clinical features, clinical management, diagnosis, treatment, and any zoonotic aspects. - Expert authors Danny W. Scott, DVM, and William H. Miller, Jr., VMD, offer years of knowledge, experience, and their vast image collections. - Diagnostic tables in each chapter provide a quick reference for identifying lesions and disorders. - An extensive list of references at the end of each chapter includes recommendations for further reading. - New coverage of dermatologic conditions includes the latest topics and emerging disorders such as chronic progressive lymphedema, herpesvirus-2-associated dermatitis, salmonella-associated dermatoses, and nodular auricular chondropathy. - Updated Diagnostic Methods chapter covers multiple methods of developing a differential diagnosis list based on breed, lesion type, patterns, and location. - A focus on common clinical problems highlights the conditions most likely to be seen in practice. - Almost 1,000 full-color photos of skin disorders make it easy to distinguish clinical characteristics and variations of normal and abnormal for accurate diagnosis and therapy.


Clinical Equine Oncology

Clinical Equine Oncology

Author: Derek C. Knottenbelt

Publisher: Saunders

Published: 2015

Total Pages: 0

ISBN-13: 9780702042669

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Diagnose common equine tumors accurately and find clinical information quickly! Clinical Equine Oncology describes the cellular basis of cancer and its etiopathogenesis, along with the principles of diagnosis, treatment, and management of cancer cases. This comprehensive resource offers more than just facts and diagrams - hundreds of detailed photographs make it easier to recognize and evaluate more than 50 types of tumors. It's useful to anyone working in the equine field, whether you're a veterinary surgeon, a practicing vet, equine dentist, or veterinary student. Written by a recognized expert on equine medicine, Derek Knottenbelt, this is the only book on the market that is completely dedicated to coverage of cancer in horses! More than 50 different types of tumor are covered, including tumors that occur in each of the 10 body systems. Over 800 excellent-quality photographs show the appearance of pathologies and cancerous conditions both before and after treatment. More than 80 full-color diagrams summarize key information. Detailed Pathology section describes common neoplasms in horses, cites research literature, and describes what is generally known about each condition. Authoritative, inclusive, and unique coverage is likely to remain the standard reference for years to come. Expert authors are recognized as the top experts in the field of equine oncology. Practical, colorful design includes icon-based references for quick appraisal of prevalence and prognosis.


pH of the Skin: Issues and Challenges

pH of the Skin: Issues and Challenges

Author: C. Surber

Publisher: Karger Medical and Scientific Publishers

Published: 2018-08-21

Total Pages: 214

ISBN-13: 3318063851

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The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle - the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.


Essentials of Stem Cell Biology

Essentials of Stem Cell Biology

Author: Robert Lanza

Publisher: Academic Press

Published: 2009-06-05

Total Pages: 681

ISBN-13: 0080884970

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First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. - Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries - Contributions by Nobel Laureates and leading international investigators - Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough - Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate - Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references