Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the
Karch’s Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices. For this edition, Dr. Karch has brought on clinical and forensic toxicology expert Dr. Bruce Goldberger, editor-in-chief of the Journal of Analytical Toxicology and president of the American Board of Forensic Toxicology, to serve as co-editor. In addition, world-renowned scientists and medical professionals have contributed their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology. Topics addressed include genetic testing in drug death investigation, pathology, toxicogenetics, alcohol, post-mortem toxicology, new psychoactive substances, the latest legal issues and challenges as well as drugs and drug testing in sports, and the ethical, legal, and practical issues involved. Vivid pictures and diagrams throughout illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. With unparalleled detail, the latest research and the highest level of authoritative medical scientific information, The Drug Abuse Handbook, Third Edition remains the definitive resource for drug related issues.
AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical app
With contributions from leading international academics across the biological sciences, this handbook takes a critical look at the key contemporary issues and debates in the field. The 31 chapters are divided into four parts: Part I Determination of Substance Misuse Part II PK and PD in Relation to Patterns of Use Part III Detection and Treatment of Drug and Alcohol Use Part IV Controversies and New Approaches This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community, and will be a vital resource to the allied professions involved in work-place drug testing, clinical toxicology, and forensic science.
The Pathology of Drug Abuse, Second Edition is a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book also offers detailed information on the origin, history, and production techniques used to make these drugs. As in the first edition, emphasis remains focused on the investigation of drug-related deaths and on practical approaches to the detection of drug abuse. The medical complications associated with each of the abused drugs are discussed in some detail as well. Individual chapters deal with cocaine, other naturally occurring stimulants, synthetic stimulants, hallucinogens, narcotics, anabolic steroids, and solvent abuse. Approximately 800 new references have been added since the publication of the first edition. Numerous new photomicrographs and drawings have been added, and many of the illustrations from the first edition have been redrawn to enhance clarity.
Forensic Issues in Alcohol Testing analyzes the acute and chronic effects of alcohol intoxication and a variety of methods with which to measure alcohol concentration in blood, urine, and breath testing. It considers variations in acute impairment by detailing the disposition and fate of alcohol in the body and factors influencing absorption, distribution, and elimination. Specific chapters address difficulties in measuring and interpreting post-mortem alcohol concentrations, recent advances in biochemical testing, and the efficacy of tests as evaluators of dependence or potential for dependence. Containing more than 40 tables, the information is extensively referenced and supported by a range of studies.
Beginning with a definition and explanation of scheduling of controlled substances, Pathology, Toxicogenetics, and Criminalistics of Drug Abuse covers investigative methods for all illegal drugs and several legitimate pharmaceuticals that are used illicitly, including steroids. It covers the latest techniques used to analyze drugs in the forensic laboratory including physical characteristics and chemical confirmatory tests. It discusses new theories and findings in toxicogenetics, details pathologic changes in the body due to drug use, and examines specific effects on the heart, lung, and central nervous system. More that 70 tables and figures illustrate and complement the text and the information is supported by extensive references
Prenatal Cocaine Exposures addresses the timely problem of maternal cocaine abuse and its effects on exposed infants, including growth retardation, learning, cardiovascular effects, and seizures. The impact of substance abuse on this and future generations presents an ongoing challenge to medical science. This comprehensive and authoritative volume reviews both animal and clinical studies to explain implications for treatment and long-term outcomes of early exposure. Prenatal Cocaine Exposures investigates the specific role of cocaine in altering fetal development. Discussions of current studies and state-of-the-art techniques provide a basis for informed clinical decisions. Pediatricians, medical specialists, basic scientists, educators, and policy makers will all benefit from the comprehensive research gathered in this volume.
Large type and uncluttered design provide quick access to pertinent information immediately. Organized into three parts, this guide provides quick access to essential and easy-to-use information required by CCRNs, CENs and CCNPs. Part 1 is a basic overview of information relating to common conditions such as cardiovascular and respiratory disorders, and provides guidelines for pharmacologic management. Part 2 lists drug monographs in alpha-organized format and focuses on critical care "Need to Know" facts. Part 3 provides you with a unique compendium of information and critical care resources presented in appendices format.
THE #1 Drug Guide for nurses & other clinicians...always dependable, always up to date! Look for these outstanding features: Completely updated nursing-focused drug monographs featuring 3,500 generic, brand-name, and combination drugs in an easy A-to-Z format NEW 32 brand-new FDA-approved drugs in this edition, including the COVID-19 drug remdesivir—tabbed and conveniently grouped in a handy “NEW DRUGS” section for easy retrieval NEW Thousands of clinical updates—new dosages and indications, Black Box warnings, genetic-related information, adverse reactions, nursing considerations, clinical alerts, and patient teaching information Special focus on U.S. and Canadian drug safety issues and concerns Photoguide insert with images of 439 commonly prescribed tablets and capsules