Infections caused by fungi have recently attracted the attention of both clinicians and basic researchers given the heavy burden they represent for any health system. The mortality and morbidity rates associated to mycosis are progressively rising simply because some of these diseases are still neglected by health-care workers and due to the changing sensitivity to antifungal drugs displayed by these organisms. In this book, both researchers and clinicians working in the medical mycology field explore the most recent literature about specific mycosis; placing in one concise chapter thoroughly revisions of the current knowledge on virulence factors, recognition by immune cells, immunoevasion, epidemiology, new diagnosis trends and therapeutics. This book is recommended to researchers, physicians and students interested in medical mycology.
This latest volume in the Current Topics in Medical Mycology series brings together internationally recognized researchers to summarize current topics of interest to medical mycologists and other scientists who are working in microbiology and immunology. A blend of contemporary, authoritative reviews and summaries of new advancements and future directions, Volume 3 aims to promote the interdisciplinary use of medically important fungi in pathogenesis, epidemiology, mycotoxins, taxonomy, and other areas where basic, applied, and clinical science are used.
The Kingdom fungi encompass a massive diversity of taxa with wide-ranging ecologies, life cycles, and morphologies ranging from unicellular aquatic chytrids to large mushrooms. Before molecular methods came in existence, taxonomists considered this Kingdom to be a member of the plant kingdom due to certain life styles like immobility and growth habitats. Molecular markers (also known as DNA markers), facilitated a better alternative method over traditional morphological methods, employed for the identification, characterization, and to understand the evolution of fungi. The morphological methods used for identification are mainly dependent on spore color or microscopic features whereas molecular markers are based on DNA polymorphism in the genomic organization. Phylogenetic studies reported in last decade, based on molecular markers, have reshaped the classification system of Kingdom fungi, which divided into one subkingdom, seven phyla, and ten subphyla. Recent advances in molecular mycology have opened the way for researchers to identify and characterize novel fungal species from unique environments. Mycology is concerned with the systematic study of fungi, including their genetic and biochemical properties, their use to humans as a source of medicine and food, as well as their dangers, such as poisoning and infections. In the 21st century with the development of DNA sequencing technologies and phylogenetic analysis based on molecular markers, new insights into fungal taxonomy were provided. This book contains a thorough discussion of molecular characterization and detection of different groups of fungi by using PCR-based markers and provides a comprehensive view of the applications and uses of different molecular markers in molecular mycology. It also addresses the recent molecular markers employed to solve the problems of identification and discusses current approaches used in molecular characterization and detection of fungi.
Environmental Mycology in Public Health: Fungi and Mycotoxins Risk Assessment and Management provides the most updated information on fungi, an essential element in the survival of our global ecology that can also pose a significant threat to the health of occupants when they are present in buildings. As the exposure to fungi in homes is a significant risk factor for a number of respiratory symptoms, including allergies and hypersensitivity pneumonitis, this book presents information on fungi and their disease agents, important aspects of exposure assessment, and their impacts on health. This book answers the hard questions, including, "How does one detect and measure the presence of indoor fungi?" and "What is an acceptable level of indoor fungi?" It then examines how we relate this information to human health problems. - Provides unique new insights on fungi and their metabolites detection in the environmental and occupational settings - Presents new information that is enriched by significant cases studies - Multi-contributed work, edited by a proficient team in medical and environmental mycology with different individual expertise - Guides the readers in the implementation of preventive and protective measures regarding exposure to fungi
Encyclopedia of Mycology, Two Volume Set provides a broad and multidisciplinary overview of a subject whose importance in an ecosystem is becoming more and more universally accepted with its close links to botany, microbiology, biotechnology and medicine. While there are many subject-specific works available on the topics presented, from a multidisciplinary point-of-view it is difficult to find a reliable and updated source such as this one. This work is unique in that it is a one-stop-shop on every topic area of this exciting field. Offers students and researchers a one-stop shop with access to a wealth of information on multiple subject areas currently only available in scattered or non-technical sources Provides an authoritative resource authored by outstanding scientists in the field who cover a range of disciplines Written in a practical and unified language, can be used for teaching or serve as a resource for researchers and managers
Theoretically translated from the 1991 Dicctionario Illustrado de Micologia, a reference for students of fungus, but in fact also updated and enlarged to include nearly twice as many terms and 80% more illustrations. Many of the some 4,000 entries include black-and- white drawings or photographs illustrating the part or feature being defined. Ulloa (botany, Universidad Nacional Autonoma de Mexico) and Hanlin (plant pathology, U. of Georgia) include the derivation of the words, most of which are from Latin. Unfortunately they do not indicate pronunciation. The cross-referencing is extensive, which mitigates the lack of an index. They also include a short bibliography and an extensive outline of the classification of the taxa they cover down to the genus level. Annotation copyrighted by Book News, Inc., Portland, OR
Laboratory Handbook of Medical Mycology summarizes the concepts dealing with the laboratory aspects of medical mycology. The publication first offers information on basic terminology and classification, laboratory safety, and clinical specimens. Discussions focus on tissue, abscess, blood, bone marrow, and urine specimens, biological hazards, disinfection and sterilization, grounding of electrical equipment, waste disposal, asexual and sexual reproduction, and vegetative growth. The text then takes a look at mold and yeast identification, including fermentation, temperature studies, asci and ascospores, zygomycetes, cycloheximide resistance, and sporulation and sterile isolates. The manuscript ponders on susceptibility testing and bioassay procedures, culture collection, and quality control. Topics include proficiency evaluations, media and equipment control, depositing unusual isolates in major culture collections, reconstituting lyophilized cultures, bioassay to determine drug levels in body fluids, and in vitro susceptibility testing. The publication is a dependable source of data for laboratory technologists, microbiologists, and mycologists engaged in safely isolating and accurately identifying fungi of medical importance.
Within the field of infectious diseases, medical mycology has experienced significant growth over the last decade. Invasive fungal infections have been increasing in many patient populations, including: those with AIDS; transplant recipients; and the elderly. As these populations grow, so does the diversity of fungal pathogens. Paralleling this development, there have been recent launches of several new antifungal drugs and therapies. Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.
The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical manifestations with accuracy. Expanded therapy content helps you implement the most appropriate treatment quickly, and a bonus CD-ROM-featuring all of the images from the text-enables you to enhance your electronic presentations. Includes specific recommendations for diagnosing, preventing, and treating fungal infections in various patient populations based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. Covers etiologic agents of disease, fungal infections in special hosts such as pediatric patients and patients with cancer and HIV, infections of specific organ systems, and more, to make you aware of the special considerations involved in certain cases. Features clinically useful and reader-friendly practical tools-including algorithms, slides, graphs, pictorials, photographs, and radiographs-that better illustrate and communicate essential points, promote efficient use in a variety of clinical and academic settings, and facilitate slide making for lectures and presentations. Offers a CD-ROM containing all of the book's images for use in your electronic presentations. Offers more clinically relevant images-more than 300 in full color for the first time-to facilitate diagnosis. Features expanded therapy-related content, including up-to-date treatment strategies and drug selection and dosing guidelines. Includes several new sections in the chapter on fungal infections in cancer patients that reflect the formidable clinical challenges these infections continue to present. Presents the work of additional international contributors who have defined many of the key issues in the field, providing more of a global perspective on the best diagnostic and management approaches. Uses a new, full-color design to enhance readability and ease of access to information.
The fungal kingdom consists of a wide variety of organisms with a diverse range of forms and functions. Fungi have been utilized for thousands of years and their importance in agriculture, medicine, food production and the environmental sciences is well known. New advances in genomic and metabolomic technologies have allowed further developments in the use of fungi in industry and medicine, increasing the need for a compilation of new applications, developments and technologies across the mycological field. Applied Mycology brings together a range of contributions, highlighting the diverse nature of current research. Chapters include discussions of fungal associations in the environment, agriculture and forestry, long established and novel applications of fungi in fermentation, the use of fungi in the pharmaceutical industry, the growing recognition of fungal infections, current interests in the use fungal enzymes in biotechnology and the new and emerging field of myconanotechnology. Demonstrating the broad coverage and importance of mycological research, this book will be of interest to researchers and students in all biological sciences.
