Introduction to Molecular Medicine
Introduction to Molecular Medicine

Author: Dennis W. Ross

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 183

ISBN-13: 1475724608

DOWNLOAD EBOOK

In the four years since the first edition of this book was published, the molecular revolution has continued. DNA has been named by Time maga zine as the Molecule of the Year, a Nobel Prize has been awarded to a young man for the invention of the polymerase chain reaction, and televi sion viewers have learned of the DNA fingerprint. Molecular technology in medicine is increasing. The availability of DNA probes for cancer suscepti bility is stressing our system of insurance, testing our ideas about medical ethics, and teaching us new things about cancer. In this edition, I have added a number of new sections, as well as a new chapter. New examples of molecular medicine have been added to demonstrate current applications of this technology. The basic concepts of molecular biology remain the basis for the first three chapters of the book. The excitement surrounding molec ular medicine that I mentioned in the preface to the first edition continues. It is now tinged with a touch of awe and a little bit of fear at the changes that recombinant DNA technology has brought to our society. v Preface to the First Edition This book describes the discoveries that have created a field called molecu lar medicine. The use of recombinant DNA technology in medical research and most recently in medical practice constitutes a revolutionary tool in our study of disease.

An Introduction to Molecular Medicine and Gene Therapy
An Introduction to Molecular Medicine and Gene Therapy

Author: Thomas F. Kresina

Publisher: John Wiley & Sons

Published: 2004-03-24

Total Pages: 408

ISBN-13: 0471461040

DOWNLOAD EBOOK

An Introduction to Molecular Medicine and Gene Therapy Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy: * Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations * Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases * Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter * Contains appendices on commercial implications and a review of the history of gene therapy This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.

Molecular Medicine
Molecular Medicine

Author: Jens Kurreck

Publisher: John Wiley & Sons

Published: 2016-02-16

Total Pages: 419

ISBN-13: 3527331891

DOWNLOAD EBOOK

Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Molecular Medicine for Clinicians
Molecular Medicine for Clinicians

Author: Barry Mendelow

Publisher: Wits University Press

Published: 2008-01-01

Total Pages: 526

ISBN-13: 1868144658

DOWNLOAD EBOOK

The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet-assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

Molecular Medicine
Molecular Medicine

Author: Sinem Nalbantoglu

Publisher: BoD – Books on Demand

Published: 2019-11-06

Total Pages: 168

ISBN-13: 183962759X

DOWNLOAD EBOOK

Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.

Principles of Molecular Medicine
Principles of Molecular Medicine

Author: J. Larry Jameson

Publisher: Springer Science & Business Media

Published: 1998-07-13

Total Pages: 1070

ISBN-13: 1592597262

DOWNLOAD EBOOK

Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.

An Introduction to Human Molecular Genetics
An Introduction to Human Molecular Genetics

Author: Jack J. Pasternak

Publisher: John Wiley & Sons

Published: 2005-06-14

Total Pages: 656

ISBN-13: 047171917X

DOWNLOAD EBOOK

An Introduction to Human Molecular Genetics Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expandsits coverage of the molecular genetics of inherited human diseaseswith the latest research findings and discoveries. Using a unique,systems-based approach, the text offers readers a thoroughexplanation of the gene discovery process and how defective genesare linked to inherited disease states in major organ and tissuesystems. All the latest developments in functional genomics,proteomics, and microarray technology have been thoroughlyincorporated into the text. The first part of the text introduces readers to the fundamentalsof cytogenetics and Mendelian genetics. Next, techniques andstrategies for gene manipulation, mapping, and isolation areexamined. Readers will particularly appreciate the text'sexceptionally thorough and clear explanation of genetic mapping.The final part features unique coverage of the molecular geneticsof distinct biological systems, covering muscle, neurological, eye,cancer, and mitochondrial disorders. Throughout the text, helpfulfigures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text'ssame lucid and engaging style, and will find a wealth of new andexpanded material that brings them fully up to date with a currentunderstanding of the field, including: * New chapters on complex genetic disorders, genomic imprinting,and human population genetics * Expanded and fully revised section on clinical genetics, coveringdiagnostic testing, molecular screening, and varioustreatments This text is targeted at upper-level undergraduate students,graduate students, and medical students. It is also an excellentreference for researchers and physicians who need a clinicallyrelevant reference for the molecular genetics of inherited humandiseases.

Molecular Pathology and the Dynamics of Disease
Molecular Pathology and the Dynamics of Disease

Author: Maika G. Mitchell

Publisher: Academic Press

Published: 2018-04-16

Total Pages: 179

ISBN-13: 0128146117

DOWNLOAD EBOOK

Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. - Assimilates theoretical knowledge with practical lab work - Provides a needed clinical perspective, along with research and theory - Highlights the impact of basic science on the practice of medicine

Lecture Notes on Molecular Medicine
Lecture Notes on Molecular Medicine

Author: John R. Bradley

Publisher: Wiley-Blackwell

Published: 2001-10-18

Total Pages: 143

ISBN-13: 9780632058396

DOWNLOAD EBOOK

Lecture Notes on Molecular Medicine provides a concise and straightforward introduction to molecular biology, explaining how it is used to understand and treat human disease. This new edition has been written in response to exciting changes in this fast-moving field. Fully updated, it explains the human genome project and how the sequence will change medicine. It also covers many new methods that have been introduced since the first edition was published. Beginning with first principles, the book is a useful primer for any science student new to molecular biology and genetics. It is also an invaluable resource for medical students and practicing doctors who need an understanding of how advances in molecular biology have impacted clinical medicine, especially in the fields of gene therapy and screening. For ease of use Lecture Notes on Molecular Medicine is divided into four sections: Basic Principles: describing the fundamentals of DNA structure and function that underpin molecular biology Biomolecular Tools: covering the manipulation of DNA and RNA and molecular techniques. Understanding Genetics: covering the basic principles of inheritance, biodiversity, gene mapping and expression and gene therapy. Molecular Medicine in Practice: discussing the profound effect which molecular biology has had on medical practice at all levels. This chapter has been greatly expanded in this new edition to cover all the latest developments in the field. A concise introduction to the basic principles & applications of molecular medicine. Explains complicated science in simple terms with clear diagrams. Integrates basic and clinical science by emphasising application to clinical medicine. Expanded chapter examining molecular medicine in clinical practice.