Intestinal Absorption of Metal Ions, Trace Elements and Radionuclides
Intestinal Absorption of Metal Ions, Trace Elements and Radionuclides

Author: S. C. Skoryna

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 466

ISBN-13: 1483160041

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Intestinal Absorption of Metal Ions, Trace Elements, and Radionuclides focuses on the transport of metal ions across biological membranes. The selection first discusses fundamental considerations of ion transport across biological membranes, including passage of ions through the pores of gels or membranes; mobilities of organic and inorganic ions in water; and complexing of alkali metal ions. The text then focuses on ion transport across membranes of high ionic selectivity and transmissivity and their uses in model studies; model systems for transcellular active transport; and detection and implications of active salt transport across biological membranes. The book takes a look at the intestinal absorption of sodium, calcium, and potassium, including sodium and potassium transport in the intestines; use of radioisotopes to assess intestinal flux of calcium in humans; and calcium and structure of cell membranes. The intestinal absorption of zinc, cobalt, and strontium and absorption of copper from the gastrointestinal tract are underscored. The selection is a recommendable source of data for readers interested in the transport of metal ions across biological membranes.

Physiologic and Chemical Basis for Metal Toxicity
Physiologic and Chemical Basis for Metal Toxicity

Author: B. Venugopal

Publisher: Springer Science & Business Media

Published: 2013-03-14

Total Pages: 245

ISBN-13: 1468429523

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Our purpose is to provide understanding for appropriate use of metals in a technical society. Knowledge of metal toxicity is needed for the preven tion, prediction, diagnosis, and therapy of adverse reactions from excess metals in mammals. Metal Toxicity in Mammals is presented in two volumes. Volume 1, Physiologic and Chemical Basis for Metal Toxic ity, provides the basis for understanding the toxic actions of metals recorded in Volume 2, Chemical Toxicity of Metals and Metalloids. The details and bases for many concepts summarized in Volume I are given, with appropriate references, in Volume 2. Thus, references for specific items in Volume 2 are not generally given in Volume 1. The authors reviewed the known toxicity of several heavy metals in anticipation of their use as multinutrient markers for NASA. As more and more metals were considered, the need for a complete review became obvious. This treatise supplants onerous searches of metal-toxicity litera ture up to 1975 and reviews the toxicity of all the metals of the periodic table on the basis of available relevant data. Books on pharmacological, nutritional, medical, veterinary, or industrial toxicity contain information about selected metals. More complete data about metals of public concern, such as mercury, lead, and cadmium, may be found in numerous books and reviews. The reader should refer to general texts and basic reference works, when specific references are not given, for general information.

Common Clinical Presentations in Dogs and Cats
Common Clinical Presentations in Dogs and Cats

Author: Ryane E. Englar

Publisher: John Wiley & Sons

Published: 2019-07-05

Total Pages: 2349

ISBN-13: 1119414601

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Common Clinical Presentations in Dogs and Cats ist ein verlässliches Referenzwerk zum schnellen Nachschlagen der wichtigsten Informationen, um Erkrankungen bei Hunden und Katzen zu diagnostizieren. Häufige klinische Zustände lassen sich anhand des problemorientierten Ansatzes erkennen. Diagnose und Behandlungspläne werden eingeführt. Das Buch ist sowohl für Studenten der Veterinärmedizin als auch Kliniker ein nützliches Nachschlagewerk mit 78 Kapiteln, die die verschiedenen Körpersysteme beschreiben. Jedes Kapitel konzentriert sich auf die Hauptbeschwerden, erläutert mögliche Diagnosen und bestimmt den klinischen Pflegeansatz. Eine Fülle von Illustrationen, klinischen Fotos und Zeichnungen veranschaulichen die präsentierten Konzepte. Common Clinical Presentations in Dogs and Cats ist ein wichtiges Referenzwerk mit den folgenden Merkmalen: - Kliniker erhalten schnellen Zugriff auf Detailinformatione, um gängige Erkrankungen bei Hunden und Katzen zu erkennen und korrekt zu diagnostizieren. - Präsentiert die Informationen nach den jeweiligen klinischen Anzeichen und zu dem entsprechenden Körpersystem. - Alle Kapitel sind einheitlich aufgebaut und ermöglichen so das schnelle Nachschlagen. - Beinhaltet Farbfotos und Zeichnungen zur Veranschaulichung der Symptome. Common Clinical Presentations in Dogs and Cats richtet sich an Veterinärmediziner für Kleintiere und Studenten der Veterinärmedizin, ist als Referenzwerk für die Praxis konzipiert und vermittelt das notwendige Fachwissen, um eine Vielzahl von Erkrankungen verlässlich zu diagnostizieren.

Copper Proteins and Copper Enzymes
Copper Proteins and Copper Enzymes

Author: Rene Lontie

Publisher: CRC Press

Published: 2018-02-06

Total Pages: 403

ISBN-13: 1351087797

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These volumes of Copper Proteins and Copper Enzymes are intended to describe the contemporary spectroscopy and other biophysical chemistry now being applied to copper proteins in order to determine the structures of their active sites. Several chapters of the treatise describe the functional understanding which is emerging from the new work. The authors are all major contributors to research progress on copper proteins and the volumes will be found to be definitive and authoritative.

Principles of Animal Extrapolation (1991)
Principles of Animal Extrapolation (1991)

Author: Edward J. Calabrese

Publisher: CRC Press

Published: 2017-11-22

Total Pages: 616

ISBN-13: 1351359045

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Principles of Animal Extrapolation addresses the conceptual basis for animal extrapolation and provides an abundance of documentation that illustrates how these principles may be applied in the selection of the more appropriate models and in the interpretation of toxicological studies. The book analyzes and documents each specific biological cause of interspecies differences in susceptibility to toxic agents, including differences in absorption, gut flora, tissue distribution, metabolism, mechanisms and efficiencies of repair, and excretion. The problem of the heterogenicity of the human population is addressed through several chapters that assess the availability and prospects of developing predictive animal models for normal humans, as well as selected potential high-risk groups. Other topics presented in this book include the biological basis of regulatory actions involving attempts to extrapolate from exceptionally high exposure levels to realistic values, especially carcinogens; an assessment of genotoxicity tests, their ability to predict carcinogenicity in whole animals, and the manner in which they should be used by regulatory agencies; birth defects; and predicting the risk of human teratogenesis. Principle of Animal Extrapolation is essential for environmental toxicologists. It also provides valuable information to biomedical scientists (especially those involved in drug development and testing) and regulatory personnel in agencies such as the EPA, the OSHA, the NIOSH, and the FDA.