Integrative Neuroscience and Personalized Medicine
Integrative Neuroscience and Personalized Medicine

Author: Charlie Graham

Publisher: Createspace Independent Publishing Platform

Published: 2018-03-21

Total Pages: 300

ISBN-13: 9781723396991

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The material provide a extensive written text appropriate as both a pithy guide to and a clear conclusion of the "science to solutions" procession in this creating field of Customized Medication and Integrative Neuroscience. The technology contains both actions of genetics using whole genome techniques and SNIPS as well as BRAINmarkers of direct thinking processes such as mind picture, biophysical changes and purpose intellectual and behavior dimensions. Customized Medication for Brain Problems will soon be a reality using the extensive quantitative and consistent ways to genomics, BRAINmarkers and intellectual operate. Each section provides a review of recent appropriate literature; show the alternatives obtained through integrative neuroscience and programs in individual good care thus offering a practical guide to the various readers. The timeliness of this book's content is propitious offering main point here information to inform exercising physicians, medical good care employees and scientists, and also a process for undergrad and graduate students interested in further their understanding of and participation in designed personal alternatives.

Integrative Neuroscience and Personalized Medicine
Integrative Neuroscience and Personalized Medicine

Author: Evian Gordon

Publisher: Oxford University Press

Published: 2011

Total Pages: 346

ISBN-13: 0195393805

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This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.

Integrative Neuroscience
Integrative Neuroscience

Author: Evian Gordon

Publisher: CRC Press

Published: 2003-09-02

Total Pages: 269

ISBN-13: 0203304764

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Most brain related activity has focussed on specialized interests within individual disciplines. Recent multidisciplinary activity has provided the impetus to break down these boundaries and encourage a freer exchange of information across disciplines. This text reflects these developments. It spans the landscape of brain science to provide core information from 12 disciplines (including evolution, philosophy, anatomy, chemistry, computer science, brain dynamics, psychology, neurology, psychiatry, psychotherapy and brain imaging). In outlining how and why it is now possible to realistically model aspects of the brain's dynamics from such a wide range of intellectual endeavors, this book will prove itself useful to undergraduates, postgraduates and all those seeking a contemporary perspective and evaluation of the current status and future directions in the brain sciences.

Personalized Medicine in Neuroscience: Molecular to System Approach
Personalized Medicine in Neuroscience: Molecular to System Approach

Author: Ali Yadollahpour

Publisher: Frontiers Media SA

Published: 2024-04-17

Total Pages: 169

ISBN-13: 2832541275

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Personalized or precision medicine (PM) is developing and adopting of the safest and most cost-effective therapeutic approach for each patient. PM approach aims to identify phenotypic and genotypic individual characteristics, observe how these parameters are correlated with the disease status, severity, and intervention responsiveness to predict the best personalized clinical protocol. On the other hand, the risk of severe toxicity and adverse effects might be related to the patient-specific characteristics.

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future
Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

Author: Silvia Mandel

Publisher: Springer Science & Business Media

Published: 2013-03-12

Total Pages: 402

ISBN-13: 9400758669

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This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection Multiple sclerosis related biomarkers: perspectives for clinical application Preventive clinical trials in brain aging: new trends & the need of guidelines MCI_ clinical guidelines in early diagnosis of dementia Alzheimer's disease: diagnostics, prognostics and the road to prevention Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms

Translational Medicine in CNS Drug Development
Translational Medicine in CNS Drug Development

Author: George G. Nomikos

Publisher: Academic Press

Published: 2019-06-18

Total Pages: 458

ISBN-13: 0128031646

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Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders Includes chapters written by international experts from industry and academia

Precision Medicine in Neurodegenerative Disorders
Precision Medicine in Neurodegenerative Disorders

Author:

Publisher: Elsevier

Published: 2023-02-14

Total Pages: 290

ISBN-13: 032390064X

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Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more

Psychoneuroimmunology
Psychoneuroimmunology

Author: Qing Yan

Publisher: Springer

Published: 2016-10-03

Total Pages: 139

ISBN-13: 3319451111

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This book provides a comprehensive overview of the cutting-edge discoveries and the systems approaches related to the multi-disciplinary field of psychoneuroimmunology (PNI), which may provide the scientific basis for mind-body relationships, and aid in the development of personalized medicine. Specifically, the book focuses on the systems biology studies of complex mechanisms, such as stress and inflammation. There is strong evidence supporting the close relationship between stress, inflammation, and disorders including obesity, cardiovascular disease, diabetes, skin diseases, and sleep disorders. As inflammation is a critical connection among different diseases, further elucidating this connection may contribute to the findings of systemic therapeutic targets. Translational medicine is also addressed, by applying PNI approaches in clinical practice. A major challenge in current bioscience is the translation of basic scientific discoveries into better clinical outcomes. With the understanding of the translational implications of PNI, integrative interventions can be applied to modulate stress responses and to promote healthier behaviors. As an important feature of this book, a broad overview of the PNI-associated integrative interventions is provided. These interventions include nutritional supplements, meditation, and other mind-body strategies. From basic concepts to systems methodologies, from theoretical sources to clinical applications, Psychoneuroimmunology contributes to the understanding and development of PNI toward the establishment of personalized and mind-body medicine.

Engineering-Medicine
Engineering-Medicine

Author: Lawrence S. Chan

Publisher: CRC Press

Published: 2019-05-15

Total Pages: 420

ISBN-13: 1351012258

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This transformative textbook, first of its kind to incorporate engineering principles into medical education and practice, will be a useful tool for physicians, medical students, biomedical engineers, biomedical engineering students, and healthcare executives. The central approach of the proposed textbook is to provide principles of engineering as applied to medicine and guide the medical students and physicians in achieving the goal of solving medical problems by engineering principles and methodologies. For the medical students and physicians, this proposed textbook will train them to “think like an engineer and act as a physician”. The textbook contains a variety of teaching techniques including class lectures, small group discussions, group projects, and individual projects, with the goals of not just helping students and professionals to understand the principles and methods of engineering, but also guiding students and professionals to develop real-life solutions. For the biomedical engineers and biomedical engineering students, this proposed textbook will give them a large framework and global perspective of how engineering principles could positively impact real-life medicine. To the healthcare executives, the goal of this book is to provide them general guidance and specific examples of applying engineering principles in implementing solution-oriented methodology to their healthcare enterprises. Overall goals of this book are to help improve the overall quality and efficiency of healthcare delivery and outcomes.

Pediatricians and Pharmacologically Trained Psychologists
Pediatricians and Pharmacologically Trained Psychologists

Author: George M. Kapalka

Publisher: Springer Science & Business Media

Published: 2011-01-20

Total Pages: 317

ISBN-13: 1441977805

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Many factors affect treatment options for children and adolescents with mental health problems, including age, severity of symptoms, financial and time constraints, and access to qualified professionals. With the limitations of managed care plans and the shrinking pool of pediatric psychiatrists, the trend is toward pediatricians prescribing psychotropic medicines. Pharmacologically trained psychologists can offer valuable assistance to pediatricians caught in this predicament. Tackling fundamental questions of when to treat as well as when and why to refer young patients, the Pediatricians and Pharmacologically Trained Psychologists examines commonly occurring pediatric conditions requiring joint treatment; reviews theoretical models of consultation and collaboration; and spotlights professional issues typically arising from these team efforts. With pertinent clarity and detail, this volume offers in-depth discussion in these key areas: Collaborative treatment of mental health conditions, including mood, disruptive, anxiety, and eating disorders. Collaborative treatment of medical conditions, focusing on gastrointestinal disorders and diabetes. Changing clinical procedures in states that have enacted prescriptive authority for psychologists. Expanding roles for pharmacologically trained psychologists practicing in states that have not enacted prescriptive authority for psychologists. Medical psychology in the pediatric hospital. Integrative care in rural settings and on the reservation. The collaborative future: brain marker technology, training paradigms, and more. Pediatricians and Pharmacologically Trained Psychologists is a must-have reference for a broad range of researchers, professionals, and graduate students, including psychologists, pediatricians and other child mental health clinicians as well as nonphysician prescribers, such as nurses, physician assistants, and pharmacists.