Silk-Based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine
Silk-Based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine

Author: Subhas C. Kundu

Publisher: Elsevier

Published: 2023-12-08

Total Pages: 908

ISBN-13: 0323960162

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Silk-based Biomaterials for Tissue Engineering, Regenerative and Precision Medicine, Second Edition is a must-have reference, providing comprehensive coverage of silk-based biomaterials and their importance in translational uses and biomedicine. This new edition considers the progress made in the past eight years, featuring many new chapters, including a discussion of cutting-edge fabrication methods and techniques, new and improved blends/composites, and an expanded range of applications in tissue engineering, regenerative and precision medicine. The book holistically reviews the types, structure and properties, processing methods, and specific biomedical applications for silk-based biomaterials. This will be a vital resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics interested in biomaterials, regenerative, and precision medicine. - Covers all key silk biomaterial types, including mulberry, Bombyx mori and nonmulberry/wild silk protein fibroins, sericins and spider silk, as well as their composite blends and various structures and scaffold platforms - Describes the cutting-edge processing techniques for each silk type, from traditional to nonconventional methods, such as using ionic liquids and engineering nanofibers and other biomedical matrices - Explores a range of applications in tissue engineering and regenerative and precision medicine, including bioprinting, bioelectronics and medical devices

Biomedical Applications of Graphene and 2D Nanomaterials
Biomedical Applications of Graphene and 2D Nanomaterials

Author: Md Nurunnabi

Publisher: Elsevier

Published: 2019-03-31

Total Pages: 402

ISBN-13: 0128162694

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Biomedical Applications of Graphene and 2D Nanomaterials provides a much-needed reference on the biomedical applications of 2D nanomaterials, as well as theoretical knowledge on their structure, physicochemical properties and biomedical applications. Chapters are dedicated to growth areas, such as size and shape-dependent chemical and physical properties and applications, such as in diagnostic and therapeutic products. The book also discusses the concept, development and preclinical studies of 2D nanomaterials-based biomedical tools, such as biosensors, artificial organs and photomedicine. Case studies and reports form the core of the book, making it an ideal resource on potential applications in biomedical science and engineering. This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications. - Presents advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials - Provides state-of-the-art biomedical applications for 2D nanomaterials, including graphene and boron nitride - Includes key information from a broad selection of subject areas for researchers in both materials, engineering and medicine

Comprehensive Biomaterials II
Comprehensive Biomaterials II

Author: Kevin Healy

Publisher: Elsevier

Published: 2017-05-18

Total Pages: 4865

ISBN-13: 0081006926

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Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Biomaterials for Artificial Organs
Biomaterials for Artificial Organs

Author: Michael Lysaght

Publisher: Elsevier

Published: 2010-12-20

Total Pages: 313

ISBN-13: 0857090844

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The worldwide demand for organ transplants far exceeds available donor organs. Consequently some patients die whilst waiting for a transplant. Synthetic alternatives are therefore imperative to improve the quality of, and in some cases, save people's lives. Advances in biomaterials have generated a range of materials and devices for use either outside the body or through implantation to replace or assist functions which may have been lost through disease or injury. Biomaterials for artificial organs reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs.Part one discusses commodity biomaterials including membranes for oxygenators and plasmafilters, titanium and cobalt chromium alloys for hips and knees, polymeric joint-bearing surfaces for total joint replacements, biomaterials for pacemakers, defibrillators and neurostimulators and mechanical and bioprosthetic heart valves. Part two goes on to investigate advanced and next generation biomaterials including small intestinal submucosa and other decullarized matrix biomaterials for tissue repair, new ceramics and composites for joint replacement surgery, biomaterials for improving the blood and tissue compatibility of total artificial hearts (TAH) and ventricular assist devices (VAD), nanostructured biomaterials for artificial tissues and organs and matrices for tissue engineering and regenerative medicine.With its distinguished editors and international team of contributors Biomaterials for artificial organs is an invaluable resource to researchers, scientists and academics concerned with the advancement of artificial organs. - Reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs - Discusses commodity biomaterials including membranes for oxygenators and cobalt chromium alloys for hips and knees and polymeric joint-bearing surfaces for total joint replacements - Further biomaterials utilised in pacemakers, defibrillators, neurostimulators and mechanical and bioprosthetic heart valve are also explored

Functionalization of Graphene
Functionalization of Graphene

Author: Vasilios Georgakilas

Publisher: John Wiley & Sons

Published: 2014-04-03

Total Pages: 507

ISBN-13: 352767277X

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All set to become the standard reference on the topic, this book covers the most important procedures for chemical functionalization, making it an indispensable resource for all chemists, physicists, materials scientists and engineers entering or already working in the field. Expert authors share their knowledge on a wide range of different functional groups, including organic functional groups, hydrogen, halogen, nanoparticles and polymers.

Engineered Nanomaterials for Innovative Therapies and Biomedicine
Engineered Nanomaterials for Innovative Therapies and Biomedicine

Author: Hemen Sarma

Publisher: Springer Nature

Published: 2022-02-21

Total Pages: 463

ISBN-13: 3030829189

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Research on biomedical applications of nanomaterials has exhibited the rapidly evolving field of biomedical sciences by showing how effective they are in treatment. These particles hold considerable potential for biomedical applications. Work is ongoing, and the results suggest a possibility for a sustainable future for nanomaterials in both therapeutic and biomedical fields. This book highlights current and emerging applications, taking global research findings into consideration. We believe the focus on the identification and role of nanomaterial applications in therapeutic and biomedical sciences can lead to novel solutions in the fields. The chapters of this book are disseminated in a manner that can be readily adopted as sources for new and further study. The editors integrate advanced texts in their research that help graduate students, researchers and professors. Additionally, we believe that international readers will be able to make use of this book for reference purposes.

Nanoengineering in Musculoskeletal Regeneration
Nanoengineering in Musculoskeletal Regeneration

Author: Mehdi Razavi

Publisher: Academic Press

Published: 2020-05-08

Total Pages: 290

ISBN-13: 0128202629

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Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline-from biomedical discovery to clinical implementation-aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation.

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering
Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering

Author: Lisa C. du Toit

Publisher: Elsevier

Published: 2020-03-08

Total Pages: 318

ISBN-13: 0128184728

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Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. - Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient - Explores the current generation of nanostructured 3D printed medical devices - Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

Tissue Engineering in Regenerative Medicine
Tissue Engineering in Regenerative Medicine

Author: Harold S. Bernstein

Publisher: Springer Science & Business Media

Published: 2011-08-28

Total Pages: 424

ISBN-13: 1617793221

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Over the past decade, significant advances in the fields of stem cell biology, bioengineering, and animal models have converged on the discipline of regenerative medicine. Significant progress has been made leading from pre-clinical studies through phase 3 clinical trials for some therapies. This volume provides a state-of-the-art report on tissue engineering toward the goals of tissue and organ restoration and regeneration. Examples from different organ systems illustrate progress with growth factors to assist in tissue remodeling; the capacity of stem cells for restoring damaged tissues; novel synthetic biomaterials to facilitate cell therapy; transplantable tissue patches that preserve three-dimensional structure; synthetic organs generated in culture; aspects of the immune response to transplanted cells and materials; and suitable animal models for non-human clinical trials. The chapters of this book are organized into six sections: Stem Cells, Biomaterials and the Extracellular Environment, Engineered Tissue, Synthetic Organs, Immune Response, and Animal Models. Each section is intended to build upon information presented in the previous chapters, and set the stage for subsequent sections. Throughout the chapters, the reader will observe a common theme of basic discovery informing clinical translation, and clinical studies in animals and humans guiding subsequent experiments at the bench.

Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles
Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles

Author: Venkatram Prasad Shastri

Publisher: Springer Science & Business Media

Published: 2010-08-14

Total Pages: 414

ISBN-13: 9048187885

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This book summarizes the NATO Advanced Research Workshop (ARW) on “Nanoengineered Systems for Regenerative Medicine” that was organized under the auspices of the NATO Security through Science Program. I would like to thank NATO for supporting this workshop via a grant to the co-directors. The objective of ARW was to explore the various facets of regenerative me- cine and to highlight role of the “the nano-length scale” and “nano-scale systems” in defining and controlling cell and tissue environments. The development of novel tissue regenerative strategies require the integration of new insights emerging from studies of cell-matrix interactions, cellular signalling processes, developmental and systems biology, into biomaterials design, via a systems approach. The chapters in the book, written by the leading experts in their respective disciplines, cover a wide spectrum of topics ranging from stem cell biology, developmental biology, ce- matrix interactions, and matrix biology to surface science, materials processing and drug delivery. We hope the contents of the book will provoke the readership into developing regenerative medicine paradigms that combine these facets into cli- cally translatable solutions. This NATO meeting would not have been successful without the timely help of Dr. Ulrike Shastri, Sanjeet Rangarajan and Ms. Sabine Benner, who assisted in the organization and implementation of various elements of this meeting. Thanks are also due Dr. Fausto Pedrazzini and Ms. Alison Trapp at NATO HQ (Brussels, Belgium). The commitment and persistence of Ms.