Mechanisms of Vascular Disease

Mechanisms of Vascular Disease

Author: Robert Fitridge

Publisher: University of Adelaide Press

Published: 2011

Total Pages: 589

ISBN-13: 1922064009

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.


Skin Tissue Engineering and Regenerative Medicine

Skin Tissue Engineering and Regenerative Medicine

Author: Mohammad Albanna

Publisher: Academic Press

Published: 2016-01-14

Total Pages: 468

ISBN-13: 012801797X

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The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. - Explores cellular and molecular processes of wound healing, scar formation, and dermal repair - Includes examples of animal models for wound healing and translation to the clinical world - Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management - Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies


Human Mesenchymal Stem Cells

Human Mesenchymal Stem Cells

Author: Mitchell Khan

Publisher: Nova Science Publishers

Published: 2021

Total Pages: 134

ISBN-13: 9781536192247

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"In Chapter 1, the COVID-19 pandemic and the damage mechanisms on the cellular level which can be ameliorated with the cellular therapies is thoroughly evaluated. Previous and ongoing stem cell clinical trial data from diseases with similar symptoms is gathered. All this accumulated data and current clinical trial results indicate that the cellular therapies could be the most effective treatment option for COVID-19 patients to ameliorate the damaged tissues and save lives. In Chapter 2, the authors examine activated mesenchymal stem cells for stroke repair. Stem Cell treatment has shown recovery in animal models of stroke, indicating an improved regenerative and repair potential. Though stem cells are still being used in clinical trials, there is no evidence that they enhance recovery in ischemic stroke patients. Nevertheless, the multipotent mesenchymal stem has widely been explored for stroke recovery. An'Activated MSC' as a therapeutic alternative to tackling ischemic stroke is proposed, thereby the activation of MSCs by cytokines, growth factors, hypoxia, pharmacological drugs, etc., could be a novel approach to improving stroke patients' responses to receiving MSCs. In Chapter 3, the potential benefits of in vitro culture of therapeutic stem cells in the presence of HB along with the ketogenic diet, whereby higher physiological concentrations of ketone bodies can be achieved in vivo, as an adjuvant to stem cell transplantation is assessed"--


Wound Healing

Wound Healing

Author: Kursad Turksen

Publisher: John Wiley & Sons

Published: 2018-02-21

Total Pages: 320

ISBN-13: 1119282489

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A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.


Skin Care in Radiation Oncology

Skin Care in Radiation Oncology

Author: Barbara Fowble

Publisher: Springer

Published: 2016-09-15

Total Pages: 241

ISBN-13: 3319314602

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This book serves as a practical guide for the prevention and treatment of radiation dermatitis. Skin toxicity caused by radiation treatment is common among cancer patients and minimizing the frequency and severity of these reactions improves quality of life and prevents interruptions that can compromise local-regional control. Each chapter is devoted to a specific disease site, such as the head and neck, breast, gastrointestinal, genitourinary, gynecologic, and central nervous system. Pediatric malignancies and wound care for locally advanced cancers are also discussed. For each topic, the range and frequency of the observed skin reactions, factors influencing these reactions, the typical course of each reaction and its resolution, and the interventions used are presented. This book provides evidence where it exists for the specific interventions and an extensive illustration program depicts the various reactions and their response to treatment protocols. Skin Care in Radiation Oncology: A Practical Guide presents a framework for patient care in an era of advancing technology and systemic and targeted therapies and is a valuable resource for radiation oncologists, dermatologists, and residents.


Nutrition and Wound Healing

Nutrition and Wound Healing

Author: Joseph A. Molnar MD PhD FACS

Publisher: CRC Press

Published: 2006-10-25

Total Pages: 384

ISBN-13: 0203500237

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With mounting evidence regarding the role of poor nutrition in the development of chronic diseases such as heart disease and diabetes, it is no secret that appropriate nutrition is crucial to optimal health. Achieving the correct balance of elements provides the body with the ability to adapt to a shifting and often hazardous environment. Never is


Textbook on Scar Management

Textbook on Scar Management

Author: Luc Téot

Publisher: Springer Nature

Published: 2020-12-07

Total Pages: 553

ISBN-13: 3030447669

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This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners


Handbook on Immunosenescence

Handbook on Immunosenescence

Author: Tamas Fulop

Publisher: Springer Science & Business Media

Published: 2009-02-27

Total Pages: 1693

ISBN-13: 1402090633

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This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.