New Insights Into Retinal Degenerative Diseases

New Insights Into Retinal Degenerative Diseases

Author: Robert E. Anderson

Publisher: Springer Science & Business Media

Published: 2001-12-31

Total Pages: 384

ISBN-13: 9780306466793

DOWNLOAD EBOOK

Since 1984, we have organized satellite symposia on retinal degenerations that are held in conjunction with the biennial International Congress of Eye Research. The timing and location of our Retinal Degeneration Symposia have allowed scientists and clinicians from around the world to convene and present their exciting new findings. The symposia have been arranged to allow ample time for discussions and one-on-one interactions in a relaxed atmosphere, where international friendships and collaborations could be established. The IXth International Symposium on Retinal Degeneration was held on October 9-14, 2000 in Durango, Colorado and was attended by over 100 scientists from six continents. This book contains many of their presentations. Several events of note occurred at this meeting. First, thanks to the generous support of the Foundation Fighting Blindness, we were able to sponsor the travel of 11 young scientists from six countries. Most of them have contributed chapters to this volume. The response to the travel program was so overwhelming that we will make it regular feature of our meeting. This will allow other bright, young investigators to be introduced to the world experts who study retinal degenerations. Second, about 40% of the scientists who attended this meeting were there for the first time. We believe that this indicates a growing interest in retinal degeneration research and ensures that new talent will be attracted to this important area of investigation. The symposium received support from several organizations.


Ocular Pathology

Ocular Pathology

Author: Myron Yanoff

Publisher:

Published: 2002

Total Pages: 792

ISBN-13:

DOWNLOAD EBOOK

The new, 5th Edition of the premier ocular pathology resource offers the latest information in the field. Over 2095 illustrations *1800 in full color* from the authors' collections represent one of the finest compilations of rare and unusual ocular conditions available. Comprehensive, yet concise, it explores new topics such as complications of corneal surgery, vascular disorders, secondary cataracts, bone-marrow transplant retinopathy, neural retinal detachment, ocular melanotic tumors, and more. Plus, a companion CD-ROM and text/CD-ROM package are available! Explores new topics such as complications of corneal surgery, vascular disorders, secondary cataracts, bone-marrow transplant retinopathy, neural retinal detachment, and ocular melanotic tumors (including diabetes). Offers expanded coverage of entities such as chromosome 17 deletion syndrome, necrobiotic xanthogranuloma, climatic protoglycan stromal keratopathy, unilateral acute idiopathic maculopathy, acute mutifocal retinitis, idiopathic polypoidal choroidal vasculopathy, North Carolina macular dystrophy, familial internal limiting membrane dystrophy, clumped pigmentary retinal dystrophy (clumped pigmentary retinal degeneration), vasoproliferative retinal tumors, Schwartz's syndrome, familial amyloidotic polyneuropathy, familial atypical mole and melanoma (FAM-M) syndrome, and more! Features specific genetic profiles for many existing entities.


Ophthalmology Examinations Review, The (Third Edition)

Ophthalmology Examinations Review, The (Third Edition)

Author: Tien Yin Wong

Publisher: World Scientific

Published: 2019-05-29

Total Pages: 552

ISBN-13: 981322102X

DOWNLOAD EBOOK

Since the last Edition of Ophthalmology Examinations Review, there has been major new discovery in the understanding of common eye diseases, and new treatments and diagnostic procedures have been refined or newly developed.A revised Edition reflecting these changes is warranted at this time. The aim and scope of the book will be consistent with the previous two editions in that it will provide a broad review for the final year ophthalmology resident and trainees taking the specialist ophthalmology examinations. The book deals primarily with key facts and topics that are important from an examination perspective. Only information and facts that are considered relevant and critical to the exams are covered, with topics that may be of scientific interest, but are not common to exams specifically left out. This book will help the resident organize and synthesize knowledge acquired from various other sources or textbooks. While not meant to replace standard textbooks, enough information is contained within the book to serve as the main revision text nearer the exams.The style and format of this book is intentionally didactic, with questions and short answers. The answer includes a 'model opening statement,' followed by a classification system to aid organization of facts and then by the bulk of the answer in concise short notes. Exam Tips are inserted to provide an insight into how to answer different types of questions and when appropriate, a Clinical Approach section is also included.In the new edition, topics such as new understanding of disease mechanisms, new investigations (e.g. OCT), and new procedures and treatment (e.g. use of anti-vascular endothelial growth factors, new refractive surgical techniques, new corneal transplant) are covered.


Retinal Pigment Epithelium in Health and Disease

Retinal Pigment Epithelium in Health and Disease

Author: Alexa Karina Klettner

Publisher: Springer Nature

Published: 2020-01-01

Total Pages: 351

ISBN-13: 3030283844

DOWNLOAD EBOOK

This book provides a contemporary resource on one of the major players in retinal diseases – the Retinal Pigment Epithelium (RPE). Throughout the book, the physiological and the pathological function of the RPE are covered on equal terms, to help readers to understand the RPE as a whole. Moreover, the development of RPE in diagnostics and therapy are covered, as well as some practical knowledge about RPE experimental models. Retinal Pigment Epithelium in Health and Disease highlights new findings of RPE research and includes the state-of-the-art knowledge of each RPE topic presented. This important feature sets this book apart from other publications, with the chapters following a design which leads from the general to the specific, to give a precise collection of the facts known. The chapters are written by well-known experts that are currently active in the field as consultants, basic scientists, and group leaders, providing expert guidance on the current aspects and future outlooks of this topic.


Advances in Vision Research, Volume II

Advances in Vision Research, Volume II

Author: Gyan Prakash

Publisher: Springer

Published: 2018-11-03

Total Pages: 464

ISBN-13: 9811308845

DOWNLOAD EBOOK

This second volume continues with a focus on the state of the art in genetic eye research in Asia and the Pacific. Though there has been an explosion of information on genetic eye research in western countries, more than sixty percent of the human genes involved in eye diseases in the Asian and Pacific population remain unknown. However, new efforts and a new awareness have sparked important discussions on the subject, and new plans are being implemented to discover the genes responsible for many eye diseases in the population. The book reviews the latest findings; its content ranges from genetic aspects of human migration to DNA sequence analysis, genome-wide association analysis, and disease phenotypes. The efforts of the Asian Eye Genetic Consortium (AEGC) are also discussed. The book’s editors have been instrumental in developing strategies for discovering the new Asian genes involved in many eye diseases. All chapters were written by leading researchers working on Asian eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume II will prove to be a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases among the Asian population.


Drug Delivery for the Retina and Posterior Segment Disease

Drug Delivery for the Retina and Posterior Segment Disease

Author: Jayvadan K. Patel

Publisher: Springer

Published: 2018-10-08

Total Pages: 490

ISBN-13: 3319958070

DOWNLOAD EBOOK

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.


Handbook of Retinal OCT: Optical Coherence Tomography E-Book

Handbook of Retinal OCT: Optical Coherence Tomography E-Book

Author: Jay S. Duker

Publisher: Elsevier Health Sciences

Published: 2021-07-31

Total Pages: 274

ISBN-13: 0323757731

DOWNLOAD EBOOK

Arguably the most important ancillary test available to ophthalmologists worldwide, optical coherence tomography (OCT) has revolutionized the field, and now includes angiographic evaluations (OCTA) that provide vascular flow data without eye injection. Handbook of Retinal OCT is an easy-to-use, high-yield guide to both OCT and OCTA imaging for practitioners at any stage of their career. Highly templated, concise, and portable, this revised edition helps you master the latest imaging methods used to evaluate retinal disease, uveitis, and optic nerve disorders. - Helps all health professionals with an interest in OCT to better and more quickly interpret OCT imaging, offering quick, highly visual guidance for evaluating age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, and much more. - Provides quick answers with bulleted, templated chapters, each focused on one specific diagnosis or group of diagnoses with a particular OCT appearance. - Demonstrates how the full spectrum of diseases presents through approximately 400 illustrations, including the highest-quality spectral-domain OCT images available and more than 50 new OCTA images. - Includes five new chapters covering optic nerve disease with retinal findings, pachychoroid diseases, paracentral acute middle maculopathy (PAMM), auto-immune retinopathies, and primary uveal lymphoma. - Offers clear visual guidance on image patterns with multiple arrows and labels throughout to highlight key details of each disease.


Fundus Autofluorescence

Fundus Autofluorescence

Author: Noemi Lois

Publisher: Lippincott Williams & Wilkins

Published: 2012-02-13

Total Pages: 303

ISBN-13: 1451152809

DOWNLOAD EBOOK

Featuring over 250 illustrations, this detailed full-color textbook provides up-to-date information on the use of fundus autofluorescence imaging in evaluation of retinal disease. Chapters describe the techniques available to image and quantify fundus autofluorescence and the autofluorescence patterns observed in the healthy eye and in various retinal diseases. Emphasis is on the value of fundus autofluorescence as a diagnostic and prognostic tool and its clinical utility in the context of other imaging techniques, such as fluorescein and indocyanine green angiography and optical coherence tomography. Each chapter also discusses the value of fundus autofluorescence in understanding the pathogenesis of the condition, and provides a comprehensive update on all aspects of the condition. A companion Website will offer the fully searchable text and an image bank.


Clinical Neuro-Ophthalmology

Clinical Neuro-Ophthalmology

Author: Ulrich Schiefer

Publisher: Springer Science & Business Media

Published: 2007-09-11

Total Pages: 320

ISBN-13: 3540327088

DOWNLOAD EBOOK

This book covers all relevant techniques of diagnosis as well as interpretations of clinical signs in Clinical Neuro-Ophthalmology. All information is highly structured, highlighting ‘definition’, ‘note’ and ‘pearl’, so that it can also be used by the physician during the patient encounter. The included flow chart posters remind the physician of the most important information. This unique and practical guide offers invaluable and practical advice for physicians treating patients with neuro-ophthalmic problems.


Transporters in Drug Discovery and Development

Transporters in Drug Discovery and Development

Author: Yurong Lai

Publisher: Woodhead Publishing

Published: 2014-08-22

Total Pages: 759

ISBN-13: 190881828X

DOWNLOAD EBOOK

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments. - A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development - Balanced coverage of molecular biology aspects and functional outcomes - State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity