The Breakthrough

The Breakthrough

Author: Charles Graeber

Publisher: Hachette+ORM

Published: 2015-12-01

Total Pages: 314

ISBN-13: 145556849X

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Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.


Immunotherapy Cancer Battle

Immunotherapy Cancer Battle

Author: Azhar ul Haque Sario

Publisher: tredition

Published: 2024-10-29

Total Pages: 190

ISBN-13: 3384401948

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Unlock the future of cancer treatment with "Immunotherapy Cancer Battle: Innovative Approaches for Success." This comprehensive guide dives deep into the revolutionary world of cancer immunotherapy, exploring the cutting-edge strategies and breakthroughs that are reshaping how we combat this relentless disease. But this book isn't just about the successes—it's also about the ongoing challenges and innovations in the field. You'll explore how scientists and clinicians are continually pushing the boundaries, combining immunotherapies with traditional treatments like chemotherapy and radiation to maximize efficacy. You'll delve into the world of tumor-infiltrating lymphocytes (TILs) and their potential for personalized treatment, as well as the promise of cancer vaccines that could one day prevent or treat cancers with unparalleled precision. Ever wondered how viruses might be used to fight cancer? You'll find out in the chapter on oncolytic virus therapy, where viruses are re-engineered to selectively infect and destroy cancer cells. Plus, you'll read about the exciting developments in adoptive cell transfer (ACT) therapies, including T-cells, natural killer (NK) cells, and cytokine-induced killer (CIK) cells, all working together to diversify and strengthen our immune responses. The book also covers innovative strategies like bispecific antibodies, which simultaneously engage two different targets, and next-generation immune checkpoints that go beyond PD-1 and CTLA-4 to offer new hope for patients. You'll gain insight into the complexities of the tumor microenvironment and how modulating it can enhance the effectiveness of immunotherapies, creating a more hostile environment for cancer to thrive. And that's not all. "Immunotherapy Cancer Battle" takes you through the futuristic applications of nanotechnology and epigenetic modulation in cancer treatment, showcasing how these cutting-edge fields are being harnessed to boost immune responses and deliver therapies more precisely than ever before. You'll discover the potential of precision immunotherapy, which tailors treatments based on individual genetic and molecular profiles, and the role of artificial intelligence in optimizing these personalized strategies. Whether you are a medical professional, researcher, or someone affected by cancer, this book is an invaluable resource that not only informs but inspires. With its comprehensive coverage and forward-looking insights, "Immunotherapy Cancer Battle: Innovative Approaches for Success" is more than just a book—it's a blueprint for the future of cancer treatment. Join us in exploring these pioneering frontiers and envision a world where cancer is no longer a death sentence but a disease we can outsmart, treat, and one day, perhaps, completely eradicate.


Policy Issues in the Clinical Development and Use of Immunotherapy for Cancer Treatment

Policy Issues in the Clinical Development and Use of Immunotherapy for Cancer Treatment

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2016-12-10

Total Pages: 135

ISBN-13: 030944232X

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Immunotherapy is a form of cancer therapy that harnesses the body's immune system to destroy cancer cells. In recent years, immunotherapies have been developed for several cancers, including advanced melanoma, lung cancer, and kidney cancer. In some patients with metastatic cancers who have not responded well to other treatments, immunotherapy treatment has resulted in complete and durable responses. Given these promising findings, it is hoped that continued immunotherapy research and development will produce better cancer treatments that improve patient outcomes. With this promise, however, there is also recognition that the clinical and biological landscape for immunotherapies is novel and not yet well understood. For example, adverse events with immunotherapy treatment are quite different from those experienced with other types of cancer therapy. Similarly, immunotherapy dosing, therapeutic responses, and response time lines are also markedly different from other cancer therapies. To examine these challenges and explore strategies to overcome them, the National Academies of Sciences, Engineering, and Medicine held a workshop in February and March of 2016. This report summarizes the presentations and discussions from the workshop.


A Cure Within

A Cure Within

Author: Neil Canavan

Publisher:

Published: 2018

Total Pages: 277

ISBN-13: 9781621822172

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Cancer. There are few words in the English language having such a visceral, personal impact. Cancer patient. Cancer survivor. Pretty much anyone over the age of 30 knows one. A family member. A friend. Someone lost too soon. Someone forever changed. But we don't really like to talk about it, because there's really not much we can do. We fight cancer, sure, but we rarely win. Defeating cancer is one of medical science's greatest challenges. So when a novel approach to treatment seems promising, there is an intense interest in its progress and those who are making it. This book is about both - the progress and the pioneers - and its focus is the revolutionary science of something called cancer immunotherapy. This medical marvel, cancer immunotherapy - also called immuno-oncology - is still in its infancy. Yet, mobilizing the immune system to recognize and attack cancer has long been imagined, and occasionally attempted, for more than 100 years: It is only just recently that significant - in fact, unprecedented - progress has been made. With the use of newly approved immunotherapy treatments, there are now reports of hundreds, if not thousands of cancer patients with advanced disease living years beyond all prior expectation. Some of these once-terminally ill patients are now called "cured." This has never happened before. As Dr. Jill O'Donnell-Tormey comments in the Foreword, "It has taken decades of basic research and billions of dollars of investment to build the foundation upon which today's lifesaving treatments are based. This book offers a uniquely entertaining yet inspiring glimpse into the lives and minds of the academic and industry pioneers who forged this new field. It is a story of how an obscure and oft-derided field of cancer research - and the tenacious few scientists who refused to abandon it - came from behind to become the new 'darling of oncology.'" The book's author, Neil Canavan, is an experienced commentator on new developments in medical science. His portraits of 25 of the pioneers in immunotherapy are the culmination of two years of travel to laboratories, offices, and conferences around the world and countless hours of conversation with individuals immersed in a vitally important, promising assault on a dread disease that kills more than eight million people each year worldwide. -- from dust jacket.


The Answer Is . . .

The Answer Is . . .

Author: Alex Trebek

Publisher: Simon & Schuster

Published: 2020-07-21

Total Pages: 304

ISBN-13: 1982157992

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A RECOMMENDED SUMMER READ BY THE NEW YORK TIMES, USA TODAY, TIME, AND NEWSWEEK Longtime Jeopardy! host and television icon Alex Trebek reflects on his life and career. Since debuting as the host of Jeopardy! in 1984, Alex Trebek has been something like a family member to millions of television viewers, bringing entertainment and education into their homes five nights a week. Last year, he made the stunning announcement that he had been diagnosed with stage four pancreatic cancer. What followed was an incredible outpouring of love and kindness. Social media was flooded with messages of support, and the Jeopardy! studio received boxes of cards and letters offering guidance, encouragement, and prayers. For over three decades, Trebek had resisted countless appeals to write a book about his life. Yet he was moved so much by all the goodwill, he felt compelled to finally share his story. “I want people to know a little more about the person they have been cheering on for the past year,” he writes in The Answer Is…: Reflections on My Life. The book combines illuminating personal anecdotes with Trebek’s thoughts on a range of topics, including marriage, parenthood, education, success, spirituality, and philanthropy. Trebek also addresses the questions he gets asked most often by Jeopardy! fans, such as what prompted him to shave his signature mustache, his insights on legendary players like Ken Jennings and James Holzhauer, and his opinion of Will Ferrell’s Saturday Night Live impersonation. The book uses a novel structure inspired by Jeopardy!, with each chapter title in the form of a question, and features dozens of never-before-seen photos that candidly capture Trebek over the years. This wise, charming, and inspiring book is further evidence why Trebek has long been considered one of the most beloved and respected figures in entertainment.


Oral, Head and Neck Oncology and Reconstructive Surgery - E-Book

Oral, Head and Neck Oncology and Reconstructive Surgery - E-Book

Author: R. Bryan Bell

Publisher: Elsevier Health Sciences

Published: 2017-08-25

Total Pages: 967

ISBN-13: 0323265693

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Oral, Head and Neck Oncology and Reconstructive Surgery is the first multidisciplinary text to provide readers with a system for managing adult head and neck cancers based upon stage. Using an evidence-based approach to the management and treatment of a wide variety of clinical conditions, the extensive experience of the author and contributors in head and neck surgery and oncology are highlighted throughout the text. This includes computer aided surgical simulation, intraoperative navigation, robotic surgery, endoscopic surgery, microvascular reconstructive surgery, molecular science, and tumor immunology. In addition, high quality photos and illustrations are included, which are easily accessible on mobile devices. - Management protocols and outcomes assessment provide clear guidelines for managing problems related to adult head and neck oncology and reconstructive surgery. - State-of-the art guidance by recognized experts details current techniques as well as technological advances in head and neck/cranio-maxillofacial surgery and oncology. - Evidence-based content details the latest diagnostic and therapeutic options for treating a wide-variety of clinical problems with an emphasis on surgical technique and outcomes. - Multidisciplinary approach reflects best practices in managing head and neck oncology and cranio-maxillofacial surgery. - 900 highly detailed images clearly demonstrate pathologies and procedures. - Designed for the modern classroom which lets you access important information anywhere through mobile tablets and smart phones.


Herbal Medicine

Herbal Medicine

Author: Iris F. F. Benzie

Publisher: CRC Press

Published: 2011-03-28

Total Pages: 500

ISBN-13: 1439807167

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The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef


Curing Cancer with Immunotherapy

Curing Cancer with Immunotherapy

Author: Rene Chee

Publisher: Foundrysoft Press

Published: 2016-08-30

Total Pages: 346

ISBN-13: 9780997820010

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Four out of ten people will be diagnosed with cancer. For decades, standard therapies have remained powerless against advanced cancer. But in the 1890s, an American surgeon showed that terminal patients could be cured by stimulating their immune systems. The treatment? A concoction of dead bacteria known as Coley's Toxins.This is the real-life story of Rene Chee, a biologist diagnosed with an aggressive cancer while working at Stanford University. After conventional treatment, she realizes it is a matter of time before her incurable cancer returns and takes her life. She and her husband explore alternative treatments and discover Coley's Toxins. Intent on a cure, they embark on an arduous adventure to obtain Coley's Toxins and other immunotherapies. They have an ally: a world-renowned immunologist who teaches them how to unleash Rene's immune system against her cancer.Through their journey, you will discover:- How cutting-edge immunotherapies work- How tumors can hide from the immune system- How to maximize immunotherapy by combining treatments- How low-carb diets and high omega-3 diets can weaken tumors- How to obtain immunotherapyAn immune-based cure is possible today. If you are ready to examine the evidence and see how it can be achieved, this book is for you.


Adjuvant Therapy for Breast Cancer

Adjuvant Therapy for Breast Cancer

Author: Monica Castiglione

Publisher: Springer Science & Business Media

Published: 2009-07-11

Total Pages: 483

ISBN-13: 0387751157

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Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.