The perfect balance of theory and practice! Here’s the practical introduction you need to understand the essential theoretical principles of clinical immunology and the serological and molecular techniques commonly used in the laboratory. You’ll begin with an introduction to the immune system; then explore basic immunologic procedures; examine immune disorders; and study the serological and molecular diagnosis of infectious disease. An easy-to-read, student-friendly approach emphasizes the direct application of theory to clinical laboratory practice. Each chapter is a complete learning module with learning outcomes, chapter outlines, theoretical principles, illustrations, and definitions of relevant terminology. Review questions and case studies help you assess your mastery of the material. A glossary at the end of the book puts must-know information at your fingertips. An access code inside new printed texts unlocks Lab Exercises and Branching Case Studies online at FADavis.com that offer more opportunities to apply theory to clinical laboratory practice.
If you're looking to succeed in today's modern laboratory environment, then you need the insightful guidance found in Immunology & Serology in Laboratory Medicine, 6th Edition. Continuing to set the standard for comprehensive coverage of immunology, this must-have resource covers everything from mastering automated techniques to understanding immunoassay instrumentation and disorders of infectious and immunologic origin. As with previous editions, trusted author, teacher and former university program director, Mary Louise Turgeon helps you build a solid foundation of knowledge and skills by taking you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you will encounter in the lab. And now with a new full-color design, additional case studies, wealth of content updates, and new features, there's never been more reason to rely on Turgeon to stretch your critical thinking skills and fully prepare for success in the clinical lab. Comprehensive immunology coverage features the latest illustrations, photographs and summary tables to help clarify various concepts and information visually. Emphasis on critical thinking utilizes case studies to challenge readers to apply their knowledge to practice. Procedural protocols move readers from immunology theory to practical aspects of the clinical lab. Chapter highlights and review questions at the end of each chapter offer opportunities for review and self-assessment. Learning objectives and key terms at the beginning of each chapter outline the important vocabulary, information, and concepts found in the chapter. Glossary at the end of the book provides a quick reference to key terms and definitions. NEW! Full color diagrams and micrographs increases comprehension and gives readers a much better sense of what they will encounter in the lab. NEW! Updated content on vaccines, tumor immunology, transplant rejection, immunotherapies, instrumentation for molecular diagnosis, the immune response, and more ensures readers are prepared for immunology in today's clinical lab. NEW! Additional case studies allow readers to apply knowledge to real world situations and stretch their critical thinking skills. NEW! Reformatted chapter review questions reflect the multiple choice styles encountered on exams.
Immunology and Serology are two major science fields. Immunology is defined as the study of the molecules, cells, organs, and systems responsible for the recognition and disposal of foreign material. Immunology began as a branch of microbiology. The study of infectious disease and the body's response to them has a major role for the development of immunology. Moreover, the concept of germ theory of disease has contributed to the field of immunology. It was Edward Jenner who first studied the response of the body to foreign substances. He observed that dairy maids who had naturally contracted a mild infection called cowpox seemed to be protected against smallpox, a horribly disfiguring disease and a major killer.Serology is the diagnostic identification of antibodies in the serum and other bodily fluids. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease).Serological tests may be performed for diagnostic purposes when an infection is suspected, in rheumatic illnesses, and in many other situations, such as checking an individual's blood type. Serology blood tests help to diagnose patients with certain immune deficiencies associated with the lack of antibodies, such as X-linked agammaglobulinemia. In such cases, tests for antibodies will be consistently negative.There are several serology techniques that can be used depending on the antibodies being studied. These include: ELISA, agglutination, precipitation, complement-fixation, and fluorescent antibodies and more recently chemiluminescence. Some serological tests are not limited to blood serum, but can also be performed on other bodily fluids such as semen and saliva, and Spinal fluid (CSF) which may contain antibodies.This book starts with a small historical introduction to Immunology. The next chapters (sections 1 to 4) give examples of Serology applied to infectious diseases (HPV, Hepatitis, Malaria and Dengue). Section 5 is dedicated to the application of serology to celiac diagnosis. Section 6 shows the application of serology to other pathogen (Lyme disease, Sjögren's syndrome, Chlamydia pneumoniae, HIV, Influenza virus, Mycobacterium, Toxoplasmosis and Leprosy). Several serologic based diagnostic techniques are used and are being developed daily, making this one of the biggest fields in science research.
The new edition of this authoritative text provides balanced coverage of basic concepts and clinical diagnostic techniques in immunology and serology. Additions to the second edition include a new chapter on Lyme disease and state-of-the-art coverage of AIDS/HIV, tumor immunology, and safety.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. This complete, up-to-date introduction to immunology takes students from basic vocabulary through common immunoassays to closer consideration of the specific diseases that require immunologic methods of diagnosis. CLINICAL IMMUNOLOGY AND SEROLOGY presents today’s newest professional techniques, thoroughly preparing students to work in modern clinical immunology laboratories, understand the data generated there, and apply the conclusions to deliver superior patient care. Full-color charts and illustrations engage students and enhance comprehension, and the text’s content has been extensively classroom-tested. It contains the most up-to-date information to accurately reflect what in done in the clinical immunology laboratory. Every chapter contains review and critical thinking questions, as well as a detailed case study.
With a new pharmacy-specific approach to immunology, Immunology for Pharmacy prepares pharmacists for practice by providing a complete understanding of the basis of immunology and the consequences of either suppressing or enhancing immune function. It covers key subjects such as prophylaxis and vaccination, antibodies as therapeutic and diagnostic agents, biological modifiers, and the rationale for use and mechanisms of therapeutic agents. Written by experienced author and educator Dennis Flaherty, this book presents topics with a logical, step-by-step approach, explaining concepts and their practical application. A companion Evolve website reinforces your understanding with flashcards and animations. - Pharmacy-specific coverage narrows the broad field of immunology to those areas most pertinent and clinically relevant to pharmacy students. - 165 full-color illustrations help to illuminate difficult concepts. - Factors That Influence the Immune Response chapter covers biological agents including bacteria, viruses, and fungi, and their related toxins and how they relate to the immune system. - Three chapters on vaccinations prepare you for this important part of the pharmacist's role by discussing cancer treatment with whole tumor vaccines, cell vaccines, and viral vector vaccines, describing other vaccines such as recombinant vaccines and plant vaccines, and examining how diseases such as diphtheria, whooping cough, and tetanus respond to vaccinations. - A summary of drugs used in treating each condition helps you understand typical treatments and their immunological mechanisms, so you can choose proper treatments. - Integrated information makes it easier to understand how various parts of the immune system work together, leading to a better understanding of immunology as a whole. - A unique focus on practical application and critical thinking shows the interrelationship of concepts and makes it easier to apply theory to practice. - Information on AIDS covers the identification and treatment of both strains of HIV as well as AIDS, preparing you for diseases you will see in practice. - Unique student-friendly features simplify your study with learning objectives and key terms at the beginning of each chapter, bulleted summaries and self-assessment questions at the end of each chapter, and a glossary at the back of the book. - Over 60 tables summarize and provide quick reference to important material. - A companion Evolve website includes animations and pharmacy terminology flashcards.
Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
