Immunogenetics: A Molecular and Clinical Overview
Immunogenetics: A Molecular and Clinical Overview

Author: Muneeb U Rehman

Publisher: Academic Press

Published: 2021-11-30

Total Pages: 412

ISBN-13: 0323903355

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A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. - Contains exclusive information about research on immunogenetics from around the globe - Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications - Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Immunogenetics and Immunodeficiency
Immunogenetics and Immunodeficiency

Author: B. Benacerraf

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 268

ISBN-13: 9401161356

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The identification of the genes which determine biological phenomena, and the study of the control they exert on these phenomena, has proven to be the most successful approach to a detailed understanding of their mechanism. The greatest advances in molecular biology have relied upon the application of the methodology of genetics to the elucidation of the fundamental processes of life at the cellular level. The same statement may be made concerning our understanding of im munological phenomena. The genetic approach has again proven extremely productive and has permitted us to identify many fundamental questions in im munobiology and to resolve some of them successfully. Among the problems with which the young discipline of immunogenetics has been concerned are the structural genes of the immunoglobulin chains. These genes have been iden tified by their control of allotypic antigenic determinants on the constant seg ment of H chains of different classes, on the constant segments of L chains and on both the constant and variable regions of rabbit H chains. These studies have provided the first evidence for the control of a single polypeptide chain by two distinct structural genes. Much has been learned concerning the genes coding the C and V regions of immunoglobulin chains (a) from the study of the inheritance of allotypic and idiotypic determinants on these chains discussed by Kunkel and Kindt and (b) from the analysis of the amino acid sequence in immunoglobulin chains from individual myeloma proteins and abnormal paraproteins, discussed by Frangione.

Janeway's Immunobiology
Janeway's Immunobiology

Author: Kenneth Murphy

Publisher: Garland Science

Published: 2010-06-22

Total Pages:

ISBN-13: 9780815344575

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The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Immunology of Aging
Immunology of Aging

Author: Ahmad Massoud

Publisher: Springer Science & Business Media

Published: 2013-11-29

Total Pages: 411

ISBN-13: 3642394957

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The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.

Immune Homeostasis
Immune Homeostasis

Author: Andrew L. Snow

Publisher: Humana Press

Published: 2013-02-09

Total Pages: 0

ISBN-13: 9781627032896

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Many questions remain unresolved as researchers continue to characterize and define the nature of normal immune homeostasis and determine how these processes are dysregulated in immunodeficiency, as well as in autoimmune and lymphoproliferative disorders. Immune Homeostasis: Methods and Protocols focuses on experimental techniques for measuring and analyzing immune cell dynamics, with a particular emphasis on examining lymphocyte programmed cell death in different contexts. With contributions by leading experts in the field, the collection examines detailed protocols for studying various pathways of apoptosis and necrosis in different types of hematopoietic cells, both in vitro and in vivo, methods for studying the maintenance of lymphocyte populations in the steady-state or following infectious challenges in both mice and humans, and technical insights into state-of-the-art genomics tools, among other topics. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Valuable and easy to use, Immune Homeostasis: Methods and Protocols serves as an important toolkit for basic and clinical scientists interested in examining various aspects of immune homeostasis in both normal and disease-related contexts in order to further study the dynamic processes that contribute to homeostasis of the immune system.

Handbook of Human Immunology
Handbook of Human Immunology

Author: Maurice R.G. O'Gorman

Publisher: CRC Press

Published: 2008-02-15

Total Pages: 642

ISBN-13: 1420003712

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Since the publication of the first edition of the Handbook of Human Immunology in 1997, major scientific achievements have directly contributed to an increased understanding of the complexities of the human immune system in health and disease. Whether as a result of the sequencing of the entire human genome, or of technological advancements, severa

Human Immunogenetics
Human Immunogenetics

Author: S. D. Litwin

Publisher: CRC Press

Published: 1989-01-10

Total Pages: 856

ISBN-13: 9780824778996

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Delineating fundamental concepts of contemporary immunogenetics, this reference/text examines specific immunogenetic systems in terms of molecular biochemistry and immunophysiology. Covers material in diverse fields, including infectious diseases, cell biology, virology, molecular genetics. Comprise

Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics
Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics

Author: Reed E. Pyeritz

Publisher: Elsevier

Published: 2024-10-23

Total Pages: 1227

ISBN-13: 0128152354

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For decades, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world's most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for students, health providers, and researchers involved in the care of patients with genetic conditions, and increasingly, all areas of health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals related to the applications of medical genetics and genomics across the full spectrum of inherited disorders and applications to medicine more broadly. In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to developmental disorders, as well as genetic conditions that affect hearing and vision. Here genetic researchers, students, and health professionals will find new and fully revised chapters on human developmental genetics, disorders affecting craniofacial development, chromosomal abnormalities, including aneuploidies and structural abnormalities, hereditary hearing impairment, and various genetic conditions of the eye. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics, Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers. · Thoroughly introduces genetic researchers, students, and healthcare professionals to the principles of human developmental genetics · Examines a wide range of developmental disorders, including craniofacial development as well as disorders affecting hearing and vision · Includes color images supporting identification, concept illustration, and method processing · Features contributions by leading international researchers and practitioners of medical genetics