Recent Advances in Pediatrics - Special Volume 22 - Immunology, Infections and Immunization
Recent Advances in Pediatrics - Special Volume 22 - Immunology, Infections and Immunization

Author: Suraj Gupte

Publisher: JP Medical Ltd

Published: 2013-06-30

Total Pages: 616

ISBN-13: 9350903660

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Special Volume 22 of Recent Advances in Pediatrics is a compilation of reviews bringing trainees and physicians fully up to date with key developments in paediatric immunology, infections and immunisation. Divided into four sections, Part 1 discusses issues and concerns in immunology, immunodeficiency and immunotherapy. Part 2 examines infections that may be encountered in children, including HIV, tuberculosis and meningococcal disease. Parts 3 and 4 cover immunisation and pharmacotherapy. Presented in an easy to follow format, Special Volume 22 follows a multidisciplinary approach. Each chapter finishes with a summary of key learning points and extensive references for further reading. Clinical photographs, illustrations and tables enhance learning. Key points New, updated volume presenting latest developments in paediatric immunology, infections and immunisation Multidisciplinary approach, easy to follow format Extensive references and key learning points summarised in each chapter Includes contributions from experts in London, Liverpool and New York

Liver Immunology
Liver Immunology

Author: M. Eric Gershwin

Publisher: Springer Nature

Published: 2020-11-03

Total Pages: 631

ISBN-13: 3030517098

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The third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver’s role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation. The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs. A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students.

Primary Immunodeficiency Disorders, An Issue of Immunology and Allergy Clinics of North America 35-4
Primary Immunodeficiency Disorders, An Issue of Immunology and Allergy Clinics of North America 35-4

Author: Anthony Montanaro

Publisher: Elsevier Health Sciences

Published: 2016-01-07

Total Pages: 193

ISBN-13: 0323413358

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This issue of Immunology and Allergy Clinics of North America, Guest Edited by Anthony Montanaro, MD, is devoted to Primary Immunodeficiency Disorders. Dr. Montanaro has assembled a group of expert authors to review the following topics: Overview of Immunodeficiency Disorder; Severe Combined Immunodeficiency Disorder; Specific Antibody Deficiencies; Common Variable Immunodeficiency; Pulmonary Manifestations of Primary Immunodeficiency Disorders; Approach to the Child with Recurrent Infections; Immunoglobulin Treatment for Primary Immunodeficiency; Bone Marrow Transplantation for Primary Immunodeficiency; and Autoimmune Manifestations of Primary Immunodeficiency.

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics
A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

Author: Xiao-Dong Chen

Publisher: Academic Press

Published: 2018-08-31

Total Pages: 548

ISBN-13: 0128119217

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A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. - Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy - Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials - Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward - Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Rheumatology and Immunology Therapy
Rheumatology and Immunology Therapy

Author: Larry W. Moreland

Publisher: Springer Science & Business Media

Published: 2004-07-20

Total Pages: 933

ISBN-13: 3540206256

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Entries in a practical A to Z Format Highly therapy-focused Uniform and clearly arranged entries for ease of reference Comprehensive information on symptoms and therapeutical possibilities of rheumatologic and musculoskeletal diseases as well as drugs Written by leading experts in the field