IgG4-Related Sclerosing Cholangitis
IgG4-Related Sclerosing Cholangitis

Author: Terumi Kamisawa

Publisher: Springer

Published: 2018-07-31

Total Pages: 141

ISBN-13: 9811045488

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This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

IgG4-related Sclerosing Cholangitis
IgG4-related Sclerosing Cholangitis

Author: Terumi Kamisawa

Publisher:

Published: 2019

Total Pages:

ISBN-13: 9789811338397

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This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

IgG4-Related Kidney Disease
IgG4-Related Kidney Disease

Author: Takao Saito

Publisher: Springer

Published: 2016-11-09

Total Pages: 298

ISBN-13: 4431556877

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This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Autoimmune Liver Disease
Autoimmune Liver Disease

Author: James Neuberger

Publisher: John Wiley & Sons

Published: 2020-04-13

Total Pages: 336

ISBN-13: 1119532604

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Ein praxisorientierter Leitfaden zu autoimmunen Lebererkrankungen, Pathogenese, Diagnose und Management. Autoimmune Liver Disease Management and Clinical Practice erläutert alles Wissenswerte zum aktuellen Forschungsstand autoimmuner Lebererkrankungen und legt dabei den Schwerpunkt auf Diagnose und Behandlung. Nach einer ausführlichen Darstellung der heutigen Erkenntnisse in der Immunologie in Verbindung mit der Autoimmunität der Leber werden die vier wichtigsten autoimmunen Lebererkrankungen bei Erwachsenen und Kindern erläutert, einschließlich Management, Rolle von Lebertransplantationen, erprobte Ansätze des Patientenmanagements und Empowerment-Ansätze. Die Autoren, Experten des Fachgebiets, untersuchen im Detail autoimmune Lebererkrankungen und geben Kliniker Handreichungen zur Patientenunterstützung. Die folgenden Themenkomplexe werden unter anderem ausführlich behandelt: - Die vier autoimmunen Lebererkrankungen, deren Diagnose und Behandlungsoptionen. - Einsatz (und Missbrauch) von Autoantikörpern bei Diagnose und Behandlung. - Rolle und Zeitpunkt von Lebertransplantationen und die Auswirkung auf wiederkehrende autoimmune Lebererkrankungen und De-novo-Autoimmunhepatitis. - Optimales Patientenmanagement und patientenbezogene Pflege. Dieses Referenzwerk zeigt umfassend, im Detail und mit alltäglichem Praxisbezug die jüngsten Entwicklungen beim Management von Lebererkrankungen und richtet sich an Ärzte, Pflegepersonal und Experten im Gesundheitswesen.

Diagnosis and Management of Cholangiocarcinoma
Diagnosis and Management of Cholangiocarcinoma

Author: James H. Tabibian

Publisher: Springer Nature

Published: 2021-05-28

Total Pages: 589

ISBN-13: 3030709361

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This book provides a comprehensive, state-of-the-art overview of cholangiocarcinoma (CCA). The text is structured to effectively present a broad yet concise overview of bile duct cancer, its relevant definitions, classification schemata, clinical management tenets, translational (including molecular and cellular) facets, and future directions. The book features numerous high-yield illustrations and is authored by an eclectic range of renowned experts in various areas of CCA, reflecting the multidisciplinary nature of the field. Filling a critical gap in the field, Diagnosis and Management of Cholangiocarcinoma: A Multidisciplinary Approach is a valuable resource for clinicians and practitioners who treat patients with bile duct cancer.

Systemic Fibroinflammatory Disorders
Systemic Fibroinflammatory Disorders

Author: Augusto Vaglio

Publisher: Springer

Published: 2017-01-09

Total Pages: 248

ISBN-13: 331941349X

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This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement. Among the conditions considered are IgG4-related disease, sclerosing cholangitis, Hashimoto’s and Riedel’s thyroiditis, retroperitoneal fibrosis/chronic periaortitis, mediastinal fibrosis, Erdheim-Chester disease, gadolinium-induced fibrosis, and sclerosing mesenteritis. This group of entities is still poorly defined and is characterized by the common denominator of chronic inflammatory infiltrate admixed with abundant fibrosis. IgG4-related disease is the prototypical example. Systemic Fibroinflammatory Disorders is the first book to draw together information on these conditions. As these diseases often require an interdisciplinary approach, the book is addressed to specialists of different disciplines, especially internists, rheumatologists, nephrologists, clinical immunologists, and hematologists.

Clinical Pancreatology for Practising Gastroenterologists and Surgeons
Clinical Pancreatology for Practising Gastroenterologists and Surgeons

Author: Juan Enrique Dominguez-Munoz

Publisher: John Wiley & Sons

Published: 2021-03-17

Total Pages: 752

ISBN-13: 111957014X

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Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.

Clinical Rounds in Hepatology
Clinical Rounds in Hepatology

Author: Virendra Singh

Publisher: Springer Nature

Published: 2022-01-29

Total Pages: 195

ISBN-13: 9811684480

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This book presents a comprehensive collection of classic cases and problem scenarios encountered as bedside case discussions during ward rounds. It facilitates the practical management of hepatic disorders. The unique aspect of hepatology involves the blend of the basic tenet of clinical medicine applied to liver disease and a multitude of interventional modalities in the management of liver, biliary, and pancreatic diseases. This book takes the reader through the process of ruling in and ruling out possibilities based on clinical data (history and examination) and then traces the logical trajectory of each case from recommended investigations to the analysis of test results and finally to making a syndromic diagnosis. By adopting an evidence-based approach, the book emphasizes analytical and need-based studies to exclude any mimics. This book helps practice hepatologists and gastroenterologists for a systematic approach towards the most common cases.

Diseases of the Gallbladder
Diseases of the Gallbladder

Author: Jae Bock Chung

Publisher: Springer Nature

Published: 2020-09-02

Total Pages: 300

ISBN-13: 9811560102

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This book provides up-to-date information on all aspects of gallbladder disease. After an introductory section on laboratory findings, pathology, and diagnostic methods, it focuses on specific conditions and their management, covering gallbladder stones, acalculous cholecystitis, gallbladder lesions associated with IgG4-related disease and with anomalous pancreaticobiliary ductal union, and dyskinesia of the gallbladder. Moreover, it discusses incidental gallbladder carcinoma in detail, including epidemiology, risk factors, gene mutations, diagnostic imaging methods and treatment modalities. The book also features a section exploring important current issues, such as the diagnosis and therapy of polypoid lesions and gallbladder wall thickening, and the role of prophylactic cholecystectomy in patients with concomitant gallstones following removal of common bile duct stones by ERCP. It also compares endoscopic gallbladder drainage with percutaneous transhepatic gallbladder drainage. Lastly, the book offers stimulating future perspectives.

Chronic Autoimmune Epithelitis
Chronic Autoimmune Epithelitis

Author:

Publisher: BoD – Books on Demand

Published: 2019-09-11

Total Pages: 122

ISBN-13: 1789852110

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Epithelial tissue does not spring to mind as an obvious source of autoimmune phenomena. Yet, genetic predisposition and influence of various environmental and epigenetic factors may lead to epithelium becoming a springboard for the development of autoimmune diseases, such as Sjögren’s syndrome, primary biliary cholangitis, autoimmune pancreatitis, or IgG4-related diseases. This book is intended as an introduction to the problem of “autoimmune epithelitis” and diseases closely related to the immune disturbances of the epithelium, with special emphasis on those affecting exocrine glands. Both theoretical and practical knowledge, presented by authors from a wide range of medical specialties, should be of help for medical professionals who have to deal with this difficult problem in their daily practice.