The Ichthyoses

The Ichthyoses

Author: Heiko Traupe

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 270

ISBN-13: 3642736505

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It is a great pleasure for me to see this work in print. As outlined by Dr. Traupe, at least 20 different types of ichthyosis have been identified to date. This book will effectively help to establish a correct diagnosis, as a basis for genetic counseling. Dr. Traupe proposes a new classification of the ichthyoses, based on reason able clinical criteria. He lets the reader share in his enormous knowledge and safely guides him through the difficult field of nomenclature. He describes the particular nature of these scaling disorders in a manner as simple as possible. During the last few years, research on ichthyosis has become a fascinating scientific challenge due to the introduction of novel investigative approaches. The main advantage of this book lies in the fact that the author successfully combines recent achievements made in lipid analysis, enzymology, electron microscopy, and molecular genetics. Heiko Traupe began his career in dermatology 11 years ago, as a resident in the Department of Dermatology in Munster. As we were both interested in the genetic aspects of skin diseases, this was the starting point of a most fruitful collaboration, which is still continuing. During our common work in Munster, Dr. Traupe was able, thanks to his unceasing clinical curiosity, to describe many novel aspects within the field of ichthyosis, and I took pride in coauthoring papers on new items such as cryptorchidism as a fea ture associated with X-linked recessive ichthyosis, autosomal dominant lamellar ichthyosis, and alopecia ichthyotica.


The Ichthyoses

The Ichthyoses

Author: R. Marks

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 207

ISBN-13: 9401098514

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Weinberg's Color Atlas of Pediatric Dermatology, Fifth Edition

Weinberg's Color Atlas of Pediatric Dermatology, Fifth Edition

Author: Leonard Kristal

Publisher: McGraw Hill Professional

Published: 2016-11-18

Total Pages: 384

ISBN-13: 0071792260

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An unsurpassed visual archive of pediatric dermatology -- with more than 300 brand-new color images! Color Atlas of Pediatric Dermatology contains a collection of more than 900 full-color images that provide invaluable guidance for the diagnosis of both common and rare skin disorders of neonates, infants, and children. For each condition reviewed in the text, one or more clinical photographs are supplied, making differential diagnosis faster, easier, and more accurate. A concise, yet thorough overview of important clinical features, etiology, prognosis, and the most current therapeutic approaches is included for each disorder illustrated. Every page reflects the book's magnificent atlas format, with photographs linked to brief text that authoritatively describes the condition illustrated in each image, along with, in most cases, a one-sentence summary of suggested treatment protocols. New treatment modalities are included when applicable, reflecting the very latest clinical findings and treatment guidelines Revised and refreshed legends throughout the text to highlight the latest thinking in pediatric dermatology practice


Ichthyoses

Ichthyoses

Author: P. Itin

Publisher: Karger Medical and Scientific Publishers

Published: 2010-09-15

Total Pages: 154

ISBN-13: 3805593953

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The various manifestations of ichthyoses are classified either by their appearance or their molecular genetics. This volume focuses on generalized, inherited disorders of cornification, which constitute an ever-enlarging group of monogenic diseases caused by a large number of genes that affect a broad array of cellular functions. The authors’ overview reflects their unique perspective that the clinical phenotype in the inherited ichthyoses mirrors a ‘best attempt’ by a metabolically compromised epidermis to maintain a barrier sufficiently impermeable for survival in a desiccating external environment.The basis for threats to survival is illuminated, and the systemic problems, including growth failure, also reflect a compromised barrier. A new consensus classification of these disorders is provided, and the distinguishing clinical features of each disorder are described. Further, the latest molecular genetic information is succinctly reviewed with up-to-date and comprehensive references. Yet, the major emphases of this volume are on disease pathogenesis and on the identification of key ultrastructural features.This publication will prove an invaluable aid to dermatologists, pediatric dermatologists and pediatricians dealing with patients with inherited ichthyoses. In addition, clinical geneticists and dermatopathologists will find it interesting reading.


European Handbook of Dermatological Treatments

European Handbook of Dermatological Treatments

Author: Andreas D. Katsambas

Publisher: Springer Science & Business Media

Published: 2013-04-17

Total Pages: 830

ISBN-13: 3662071312

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Dermatology is a specialty in the field of medicine which constantly changes at a vast rate. Alongside technology, new drugs, methods and treatments are continuously developed for the treatment of all common skin diseases. The first edition of the European Handbook of Dermatological Treatments received an overwhelming response from dermatovenereologists all over Europe. Its easy-to-read format, which is also used for this 2nd edition, is aimed at helping the physician to obtain comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. This new edition provides an excellent update including the newest developments of drugs, methods and treatments in dermatological practice, maintaining the clear structure and well-proven format. It is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.


Pigmented Ethnic Skin and Imported Dermatoses

Pigmented Ethnic Skin and Imported Dermatoses

Author: Constantin E. Orfanos

Publisher: Springer

Published: 2018-08-14

Total Pages: 515

ISBN-13: 3319694227

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The vast majority of the global population has pigmented non-Caucasian skin; accordingly, this book focuses on the diagnosis and management of skin diseases in dark-skinned populations, paying particular attention to different reactive profiles, the frequency and the clinical pictures of diseases in pigmented ethnic skin that arise in hot climate zones. Supplemented by a wealth of high-quality, full-color images, this comprehensive work covers the full range of dermatological entities and issues characteristic of the tropical and subtropical regions of the globe, including those that are now emerging in developed countries as a result of intensified travel, globalized business, and migration. Each disorder is described by respected experts on subtropical and tropical countries, and each chapter is clearly structured, examining the incidence, pathogenesis, clinical presentation, management and course. The book illustrates the clinical features and includes major schedules for the diagnosis and management of skin diseases presented in darkly pigmented to black skin. As such, it offers an invaluable tool for all dermatologists in developing and developed countries, especially those who are used to dealing with skin lesions mainly in white Caucasian skin. While enabling physicians to provide proper advice, medical services and support, Pigmented Ethnic Skin and Imported Dermatoses also represents a guide for a broader range of professionals working for governmental institutions, health and refugee agencies.


Skin Barrier

Skin Barrier

Author: Peter M. Elias

Publisher: CRC Press

Published: 2005-09-22

Total Pages: 634

ISBN-13: 084936129X

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A must-have reference for any researcher or scientist interested in cutaneous protective mechanisms, this guide provides expertly researched chapters on every aspect of stratum corneum structure, function, and development, as well as detailed sections on barrier-repair strategies and the role of barrier function in diseases such as atopic dermatiti


Transporters in Drug Discovery and Development

Transporters in Drug Discovery and Development

Author: Yurong Lai

Publisher: Woodhead Publishing

Published: 2014-08-22

Total Pages: 759

ISBN-13: 190881828X

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Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments. - A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development - Balanced coverage of molecular biology aspects and functional outcomes - State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity


Genetic Skin Disorders

Genetic Skin Disorders

Author: Virginia P. Sybert

Publisher: Oxford University Press

Published: 2017-01-02

Total Pages: 512

ISBN-13: 0190276487

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This fully revised and updated edition of GENETIC SKIN DISORDERS reflects the most current understanding of the diagnosis, treatment, genetic basis, and differential diagnoses of inherited skin disorders. Organized with the needs of busy clinicians in mind, it offers detailed clinical guidance on the signs, symptoms, mode of inheritance, recurrence risk, and diagnosis of over 300 skin disorders, all in an accessible, at-a-glance format. Annotated bibliographies highlight the most relevant and up-to-date medical literature. Newly compiled lists of support groups, both national and international, for patients and their families supplement the ample resources for medical professionals. Informed by the author's extensive clinical experience and suffused with a distinctive, witty voice, GENETIC SKIN DISORDERS is an ideal companion in the laboratory, clinic, or consulting room. FEATURES · Includes both disease-based chapters and an appendix of skin signs that simplifies differential diagnosis for specialists and general practitioners alike · More than 800 color photographs illustrate the full spectrum of hair, skin, and nail abnormalities · Updated to reflect current classification of inherited skin disorders and the molecular underpinnings of these conditions


Syndromes: Rapid Recognition and Perioperative Implications

Syndromes: Rapid Recognition and Perioperative Implications

Author: Bruno Bissonnette

Publisher: McGraw-Hill Education / Medical

Published: 2006-08-10

Total Pages: 988

ISBN-13:

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Essential medical facts on over 2,000 genetic syndromes. Organized alphabetically, this book provides comprehensive medical coverage for each syndrome, from genetic basis to manifestations to related medical considerations.