Human Population Genetics

Human Population Genetics

Author: John H. Relethford

Publisher: John Wiley & Sons

Published: 2012-03-27

Total Pages: 326

ISBN-13: 0470464674

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Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf


Human Population Genetics and Genomics

Human Population Genetics and Genomics

Author: Alan R. Templeton

Publisher: Academic Press

Published: 2018-11-08

Total Pages: 498

ISBN-13: 0123860261

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Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now


Introduction to Population Genetics

Introduction to Population Genetics

Author: Richard Halliburton

Publisher: Pearson

Published: 2004

Total Pages: 680

ISBN-13:

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Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization. It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species. For an introduction to, and understanding of, population genetics.


Human Population Genomics

Human Population Genomics

Author: Kirk E. Lohmueller

Publisher: Springer Nature

Published: 2021-03-13

Total Pages: 236

ISBN-13: 3030616460

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This textbook provides a concise introduction and useful overview of the field of human population genomics, making the highly technical and contemporary aspects more accessible to students and researchers from various fields. Over the past decade, there has been a deluge of genetic variation data from the entire genome of individuals from many populations. These data have allowed an unprecedented look at human history and how natural selection has impacted humans during this journey. Simultaneously, there have been increased efforts to determine how genetic variation affects complex traits in humans. Due to technological and methodological advances, progress has been made at determining the architecture of complex traits. Split in three parts, the book starts with the basics, followed by more advanced and current research. The first part provides an introduction to essential concepts in population genetics, which are relevant for any organism. The second part covers the genetics of complex traits in humans. The third part focuses on applying these techniques and concepts to genetic variation data to learn about demographic history and natural selection in humans. This new textbook aims to serve as a gateway to modern human population genetics research for those new to the field. It provides an indispensable resource for students, researchers and practitioners from disparate areas of expertise.


Progress in Population Genetics and Human Evolution

Progress in Population Genetics and Human Evolution

Author: Peter Donnelly

Publisher: Springer Verlag

Published: 1997-02-27

Total Pages: 328

ISBN-13:

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This book is devoted to the collection, interpretation and analysis of population genetic data. Among the topics included here are studies on human evolutionary history, molecular techniques for generating data, statistical and computational techniques for the interpretation of such data, and stochastic models for genealogy and population structure. The chapters reflect the close interaction between experimental molecular biologists and theoreticians. The book will be useful for specialists in the area, as well as mathematicians, statisticians, computer scientists and biologists wanting a brief overview of current problems in the field.


Human Population Genetics

Human Population Genetics

Author: P.P. Majumder

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 558

ISBN-13: 1461529700

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J. B. S. Haldane, R. A. Fisher and Sewall Wright simultaneously, and largely independently, laid the foundations of population genetics and the mathematical theory of evolution. Hal dane was born on November 5, 1892. Although he primarily worked at the University College London (UCL), in 1957 he resigned from the UCL and joined the Indian Statistical Institute, Calcutta (India) as a Research Professor. In celebration of his birth centenary, the Indian Statistical Institute organized an International Conference on Human Genetics from 15 to 19 December, 1992. The prime motive in holding this Conference was to bring together a group of scientists - geneticists, anthropologists, clinicians and statisticians - to evaluate the impact of Haldane's contributions to various areas of human genetics, and also to review recent developments in the subject. Session and lecture themes were so chosen that they covered areas theoretical and applied, classical and emerging. Speakers were then identified and invited to deliver lectures on these themes. Manuscripts of all invited presentations and a selected number of contributed presentations were considered for inclusion in this Proceed ings Volume. Each manuscript was reviewed by at least one Conference participant, which resulted in revision of several manuscripts and rejection of some. This volume is a collection of the manuscripts which have been 'accepted' after the review-process. The Conference began with the "J. B. S. Haldane Centenary Lecture" delivered by C. R. Rao.


Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: John Wiley & Sons

Published: 2006-09-29

Total Pages: 720

ISBN-13: 0470047216

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The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links


The Genetics of Human Populations

The Genetics of Human Populations

Author: Luigi Luca Cavalli-Sforza

Publisher: Courier Corporation

Published: 1999-01-01

Total Pages: 994

ISBN-13: 0486406938

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Comprehensive, advanced treatment of nature and source of inherited characteristics, with treatment of mathematical techniques. Mendelian populations, mutations, polymorphisms, genetic demography, much more. Emphasizes interpretation of data in relation to theoretical models.


The Genetic Structure of Populations

The Genetic Structure of Populations

Author: A. Jacquard

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 585

ISBN-13: 3642884156

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It is part of the ideology of science that it is an international enterprise, carried out by a community that knows no barriers of nation or culture. But the reality is somewhat different. Despite the best intentions of scientists to form a single community, unseparated by differences of national and political viewpoint, they are, in fact, separated by language. Scientific literature in German is not generally assimilated by French workers, nor that appearing in French by those whose native language is English. The problem appears to have become more severe since the last war, because the ascendance of the United States as the preeminent economic power led, in a time of big and expensive science, to a pre dominance of American scientific production and a growing tendency (at least among English-speakers) to regard English as the international language of science. International congresses and journals of world circulation have come more and more to take English as their standard or official language. As a result, students and scientific workers in the English speaking world have become more linguistically parochial than ever before and have been cut off from a considerable scientific literature. Population genetics has been no exception to the rule. The elegant and extremely innovative theoreticaI work of Malecot, for example, is only now being properly assimilated by population biologists outside France. It was therefore with some sense of frustration that I read Prof.