Molecular Biology of the Cell
Author:
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
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Mapping and Sequencing the Human Genome
Author: National Research Council
Publisher: National Academies Press
Published: 1988-01-01
Total Pages: 128
ISBN-13: 0309038405
DOWNLOAD EBOOKThere is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
The Globe Artichoke Genome
Author: Ezio Portis
Publisher: Springer
Published: 2019-06-08
Total Pages: 238
ISBN-13: 3030200124
DOWNLOAD EBOOKThis book presents the latest information on the genetics and genomics of the globe artichoke. It focuses on the latest findings, tools and strategies employed in genome sequencing, physical map development and QTL analyses, as well as genomic resources. The re-sequencing of four globe artichoke genotypes, representative of the core varietal types in cultivation, as well as the genotype of cultivated cardoon, has recently been completed. Here, the five genomes are reconstructed at the chromosome scale and annotated. Moreover, functional SNP analyses highlight numerous genetic variants, which represent key tools for dissecting the path from sequence variation to phenotype, as well as for designing effective diagnostic markers. The wealth of information provided here offers a valuable asset for scientists, plant breeders and students alike.
Mapping our genes : the genome projects : how big, how fast?
Author:
Publisher: DIANE Publishing
Published: 1988
Total Pages: 215
ISBN-13: 142892258X
DOWNLOAD EBOOKThe Potato Genome
Author: Swarup Kumar Chakrabarti
Publisher: Springer
Published: 2017-12-26
Total Pages: 332
ISBN-13: 3319661353
DOWNLOAD EBOOKThis book describes the historical importance of potato (Solanum tuberosum L.),potato genetic resources and stocks (including S. tuberosum group Phureja DM1-3 516 R44, a unique doubled monoploid homozygous line) used for potato genome sequencing. It also discusses strategies and tools for high-throughput sequencing, sequence assembly, annotation, analysis, repetitive sequences and genotyping-by-sequencing approaches. Potato (Solanum tuberosum L.; 2n = 4x = 48) is the fourth most important food crop of the world after rice, wheat and maize and holds great potential to ensure both food and nutritional security. It is an autotetraploid crop with complex genetics, acute inbreeding depression and a highly heterozygous nature. Further, the book examines the recent discovery of whole genome sequencing of a few wild potato species genomes, genomics in management and genetic enhancement of Solanum species, new strategies towards durable potato late blight resistance, structural analysis of resistance genes, genomics resources for abiotic stress management, as well as somatic cell genetics and modern approaches in true-potato-seed technology. The complete genome sequence provides a better understanding of potato biology, underpinning evolutionary process, genetics, breeding and molecular efforts to improve various important traits involved in potato growth and development.
Heritable Human Genome Editing
Author: The Royal Society
Publisher: National Academies Press
Published: 2021-01-16
Total Pages: 239
ISBN-13: 0309671132
DOWNLOAD EBOOKHeritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
50 Years of DNA
Author: J. Clayton
Publisher: Springer
Published: 2016-04-30
Total Pages: 145
ISBN-13: 1137117818
DOWNLOAD EBOOKCrick and Watson's discovery of the structure of DNA fifty years ago marked one of the great turning points in the history of science. Biology, immunology, medicine and genetics have all been radically transformed in the succeeding half-century, and the double helix has become an icon of our times. This fascinating exploration of a scientific phenomenon provides a lucid and engaging account of the background and context for the discovery, its significance and afterlife, while a series of essays by leading scientists, historians and commentators offers uniquely individual perspectives on DNA and its impact on modern science and society.
Lepidoptera Genetics
Author: Roy Robinson
Publisher: Elsevier
Published: 2017-04-27
Total Pages: 698
ISBN-13: 148315470X
DOWNLOAD EBOOKLepidoptera Genetics provides a systematic account of the genetics and karyology of Lepidoptera. Topics covered include the use of biometry in genetic studies; population genetics and polymorphism; the rise of industrial melanism; and the evolution of mimicry. The genetics of Rhopalocera and Heterocera is also discussed. This book is comprised of eight chapters and begins with an overview of Lepidoptera species and their genetics, paying particular attention to color and pigmentation, breeding, and resistance to insecticides, as well as the effect of seasonal variations and the environment on Lepidoptera. The next chapter outlines the tenets of genetics that are of value for Lepidoptera research, including particulate heredity, random assortment, sex-linked inheritance, maternal inheritance, and mosaicism. The reader is methodically introduced to the application of biometry to the study of Lepidoptera genetics; the evolution of mimicry in Lepidoptera; and the known heredity of Rhopalocera and Heterocera. The final chapter examines the karyology of Lepidoptera, focusing on the haploid karyotype, polyploidy, chiasmata frequency, supernumerary chromosomes, and sex chromatin. This monograph will be a useful resource for entomologists, geneticists, and biologists.
The Barley Genome
Author: Nils Stein
Publisher: Springer
Published: 2018-08-18
Total Pages: 400
ISBN-13: 3319925288
DOWNLOAD EBOOKThis book presents an overview of the state-of-the-art in barley genome analysis, covering all aspects of sequencing the genome and translating this important information into new knowledge in basic and applied crop plant biology and new tools for research and crop improvement. Unlimited access to a high-quality reference sequence is removing one of the major constraints in basic and applied research. This book summarizes the advanced knowledge of the composition of the barley genome, its genes and the much larger non-coding part of the genome, and how this information facilitates studying the specific characteristics of barley. One of the oldest domesticated crops, barley is the small grain cereal species that is best adapted to the highest altitudes and latitudes, and it exhibits the greatest tolerance to most abiotic stresses. With comprehensive access to the genome sequence, barley’s importance as a genetic model in comparative studies on crop species like wheat, rye, oats and even rice is likely to increase.
FGCS '92
Author:
Publisher: IOS Press
Published: 1992
Total Pages: 498
ISBN-13: 9789051990997
DOWNLOAD EBOOKThe FGCS project was introduced at a congerence in 1981 and commenced the following year. This volume contains the reports on the final phase of the project, showing how the research goals set were achieved.
